SNF30_SCHPO
ID SNF30_SCHPO Reviewed; 274 AA.
AC Q9P7S6;
DT 02-SEP-2008, integrated into UniProtKB/Swiss-Prot.
DT 01-OCT-2000, sequence version 1.
DT 03-AUG-2022, entry version 100.
DE RecName: Full=SWI/SNF chromatin-remodeling complex subunit snf30;
DE AltName: Full=SWI/SNF complex subunit snf30;
GN Name=snf30; ORFNames=SPAC23G3.07c;
OS Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina;
OC Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae;
OC Schizosaccharomyces.
OX NCBI_TaxID=284812;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=972 / ATCC 24843;
RX PubMed=11859360; DOI=10.1038/nature724;
RA Wood V., Gwilliam R., Rajandream M.A., Lyne M.H., Lyne R., Stewart A.,
RA Sgouros J.G., Peat N., Hayles J., Baker S.G., Basham D., Bowman S.,
RA Brooks K., Brown D., Brown S., Chillingworth T., Churcher C.M., Collins M.,
RA Connor R., Cronin A., Davis P., Feltwell T., Fraser A., Gentles S.,
RA Goble A., Hamlin N., Harris D.E., Hidalgo J., Hodgson G., Holroyd S.,
RA Hornsby T., Howarth S., Huckle E.J., Hunt S., Jagels K., James K.D.,
RA Jones L., Jones M., Leather S., McDonald S., McLean J., Mooney P.,
RA Moule S., Mungall K.L., Murphy L.D., Niblett D., Odell C., Oliver K.,
RA O'Neil S., Pearson D., Quail M.A., Rabbinowitsch E., Rutherford K.M.,
RA Rutter S., Saunders D., Seeger K., Sharp S., Skelton J., Simmonds M.N.,
RA Squares R., Squares S., Stevens K., Taylor K., Taylor R.G., Tivey A.,
RA Walsh S.V., Warren T., Whitehead S., Woodward J.R., Volckaert G., Aert R.,
RA Robben J., Grymonprez B., Weltjens I., Vanstreels E., Rieger M.,
RA Schaefer M., Mueller-Auer S., Gabel C., Fuchs M., Duesterhoeft A.,
RA Fritzc C., Holzer E., Moestl D., Hilbert H., Borzym K., Langer I., Beck A.,
RA Lehrach H., Reinhardt R., Pohl T.M., Eger P., Zimmermann W., Wedler H.,
RA Wambutt R., Purnelle B., Goffeau A., Cadieu E., Dreano S., Gloux S.,
RA Lelaure V., Mottier S., Galibert F., Aves S.J., Xiang Z., Hunt C.,
RA Moore K., Hurst S.M., Lucas M., Rochet M., Gaillardin C., Tallada V.A.,
RA Garzon A., Thode G., Daga R.R., Cruzado L., Jimenez J., Sanchez M.,
RA del Rey F., Benito J., Dominguez A., Revuelta J.L., Moreno S.,
RA Armstrong J., Forsburg S.L., Cerutti L., Lowe T., McCombie W.R.,
RA Paulsen I., Potashkin J., Shpakovski G.V., Ussery D., Barrell B.G.,
RA Nurse P.;
RT "The genome sequence of Schizosaccharomyces pombe.";
RL Nature 415:871-880(2002).
RN [2]
RP SUBCELLULAR LOCATION [LARGE SCALE ANALYSIS].
RX PubMed=16823372; DOI=10.1038/nbt1222;
RA Matsuyama A., Arai R., Yashiroda Y., Shirai A., Kamata A., Sekido S.,
RA Kobayashi Y., Hashimoto A., Hamamoto M., Hiraoka Y., Horinouchi S.,
RA Yoshida M.;
RT "ORFeome cloning and global analysis of protein localization in the fission
RT yeast Schizosaccharomyces pombe.";
RL Nat. Biotechnol. 24:841-847(2006).
RN [3]
RP IDENTIFICATION IN THE SWI/SNF COMPLEX, FUNCTION OF THE SWI/SNF COMPLEX, AND
RP IDENTIFICATION BY MASS SPECTROMETRY.
RX PubMed=18622392; DOI=10.1038/nsmb.1452;
RA Monahan B.J., Villen J., Marguerat S., Baehler J., Gygi S.P., Winston F.;
RT "Fission yeast SWI/SNF and RSC complexes show compositional and functional
RT differences from budding yeast.";
RL Nat. Struct. Mol. Biol. 15:873-880(2008).
CC -!- FUNCTION: Component of the SWI/SNF complex, an ATP-dependent chromatin
CC remodeling complex, required for the positive and negative regulation
CC of gene expression of a large number of genes. It changes chromatin
CC structure by altering DNA-histone contacts within a nucleosome, leading
CC eventually to a change in nucleosome position, thus facilitating or
CC repressing binding of gene-specific transcription factors.
CC {ECO:0000269|PubMed:18622392}.
CC -!- SUBUNIT: Component of the SWI/SNF global transcription activator
CC complex composed of at least arp9, arp42, snf5, snf22, snf30, sbf59,
CC sol1, ssr1, ssr2, ssr3, ssr4 and tfg3. {ECO:0000269|PubMed:18622392}.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000269|PubMed:16823372}. Nucleus
CC {ECO:0000269|PubMed:16823372}.
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DR EMBL; CU329670; CAB72232.1; -; Genomic_DNA.
DR PIR; T50181; T50181.
DR RefSeq; NP_593107.1; NM_001018504.2.
DR AlphaFoldDB; Q9P7S6; -.
DR BioGRID; 278274; 27.
DR ComplexPortal; CPX-6362; SWI/SNF chromatin remodelling complex.
DR DIP; DIP-48387N; -.
DR IntAct; Q9P7S6; 11.
DR STRING; 4896.SPAC23G3.07c.1; -.
DR iPTMnet; Q9P7S6; -.
DR MaxQB; Q9P7S6; -.
DR PaxDb; Q9P7S6; -.
DR EnsemblFungi; SPAC23G3.07c.1; SPAC23G3.07c.1:pep; SPAC23G3.07c.
DR GeneID; 2541781; -.
DR KEGG; spo:SPAC23G3.07c; -.
DR PomBase; SPAC23G3.07c; snf30.
DR VEuPathDB; FungiDB:SPAC23G3.07c; -.
DR HOGENOM; CLU_1016188_0_0_1; -.
DR InParanoid; Q9P7S6; -.
DR OMA; TRYMRRI; -.
DR PRO; PR:Q9P7S6; -.
DR Proteomes; UP000002485; Chromosome I.
DR GO; GO:0032153; C:cell division site; HDA:PomBase.
DR GO; GO:0000785; C:chromatin; IC:ComplexPortal.
DR GO; GO:0005829; C:cytosol; HDA:PomBase.
DR GO; GO:0005634; C:nucleus; HDA:PomBase.
DR GO; GO:0016514; C:SWI/SNF complex; IDA:PomBase.
DR GO; GO:0006338; P:chromatin remodeling; IC:ComplexPortal.
DR GO; GO:1905168; P:positive regulation of double-strand break repair via homologous recombination; IC:ComplexPortal.
DR GO; GO:0006357; P:regulation of transcription by RNA polymerase II; IPI:PomBase.
PE 1: Evidence at protein level;
KW Chromatin regulator; Cytoplasm; Nucleus; Reference proteome; Transcription;
KW Transcription regulation.
FT CHAIN 1..274
FT /note="SWI/SNF chromatin-remodeling complex subunit snf30"
FT /id="PRO_0000349431"
FT REGION 123..167
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 274 AA; 30423 MW; 6C746130FDBE3524 CRC64;
MSFVSKSPPI VNSASPTGQV NPMEVEKANK LLEINRLILW KCLELQHIKT AQNSTLEQRA
LSTELFNSYI QRLKANLAFV VSIASPRQMQ VLTPPLSCPE SLPQLEPLYK ELRQYFQIAQ
TSTLSYPPSN GDSSSYANGT DLHGNTGTMQ QEEKANPSLT RSDSVSSGSY ITMQGANSLK
AQQDLLNSFT GAPSNNSHNI PDPNLSQTFS ATSMGPPNNN YSKFRTDNYL ARSSNRSGTP
NIQNEQSRFF DSQQAQVQAR ALMQRYQQGM EFNK
