SNF7_SCHPO
ID SNF7_SCHPO Reviewed; 222 AA.
AC Q9P7F7;
DT 22-NOV-2005, integrated into UniProtKB/Swiss-Prot.
DT 01-OCT-2000, sequence version 1.
DT 03-AUG-2022, entry version 109.
DE RecName: Full=Vacuolar-sorting protein snf7;
DE AltName: Full=Vacuolar protein-sorting-associated protein 32;
GN Name=snf7; Synonyms=vps32; ORFNames=SPAC1142.07c;
OS Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina;
OC Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae;
OC Schizosaccharomyces.
OX NCBI_TaxID=284812;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=972 / ATCC 24843;
RX PubMed=11859360; DOI=10.1038/nature724;
RA Wood V., Gwilliam R., Rajandream M.A., Lyne M.H., Lyne R., Stewart A.,
RA Sgouros J.G., Peat N., Hayles J., Baker S.G., Basham D., Bowman S.,
RA Brooks K., Brown D., Brown S., Chillingworth T., Churcher C.M., Collins M.,
RA Connor R., Cronin A., Davis P., Feltwell T., Fraser A., Gentles S.,
RA Goble A., Hamlin N., Harris D.E., Hidalgo J., Hodgson G., Holroyd S.,
RA Hornsby T., Howarth S., Huckle E.J., Hunt S., Jagels K., James K.D.,
RA Jones L., Jones M., Leather S., McDonald S., McLean J., Mooney P.,
RA Moule S., Mungall K.L., Murphy L.D., Niblett D., Odell C., Oliver K.,
RA O'Neil S., Pearson D., Quail M.A., Rabbinowitsch E., Rutherford K.M.,
RA Rutter S., Saunders D., Seeger K., Sharp S., Skelton J., Simmonds M.N.,
RA Squares R., Squares S., Stevens K., Taylor K., Taylor R.G., Tivey A.,
RA Walsh S.V., Warren T., Whitehead S., Woodward J.R., Volckaert G., Aert R.,
RA Robben J., Grymonprez B., Weltjens I., Vanstreels E., Rieger M.,
RA Schaefer M., Mueller-Auer S., Gabel C., Fuchs M., Duesterhoeft A.,
RA Fritzc C., Holzer E., Moestl D., Hilbert H., Borzym K., Langer I., Beck A.,
RA Lehrach H., Reinhardt R., Pohl T.M., Eger P., Zimmermann W., Wedler H.,
RA Wambutt R., Purnelle B., Goffeau A., Cadieu E., Dreano S., Gloux S.,
RA Lelaure V., Mottier S., Galibert F., Aves S.J., Xiang Z., Hunt C.,
RA Moore K., Hurst S.M., Lucas M., Rochet M., Gaillardin C., Tallada V.A.,
RA Garzon A., Thode G., Daga R.R., Cruzado L., Jimenez J., Sanchez M.,
RA del Rey F., Benito J., Dominguez A., Revuelta J.L., Moreno S.,
RA Armstrong J., Forsburg S.L., Cerutti L., Lowe T., McCombie W.R.,
RA Paulsen I., Potashkin J., Shpakovski G.V., Ussery D., Barrell B.G.,
RA Nurse P.;
RT "The genome sequence of Schizosaccharomyces pombe.";
RL Nature 415:871-880(2002).
CC -!- FUNCTION: Required for the sorting and concentration of proteins
CC resulting in the entry of these proteins into the invaginating vesicles
CC of the multivesicular body (MVB). {ECO:0000250}.
CC -!- SUBUNIT: A component of the endosomal sorting required for transport
CC complex III (ESCRT-III). {ECO:0000250}.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250}. Endosome membrane
CC {ECO:0000250}; Peripheral membrane protein {ECO:0000250}.
CC -!- SIMILARITY: Belongs to the SNF7 family. {ECO:0000305}.
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DR EMBL; CU329670; CAB77014.1; -; Genomic_DNA.
DR RefSeq; NP_594271.1; NM_001019694.2.
DR AlphaFoldDB; Q9P7F7; -.
DR SMR; Q9P7F7; -.
DR BioGRID; 279363; 7.
DR STRING; 4896.SPAC1142.07c.1; -.
DR iPTMnet; Q9P7F7; -.
DR MaxQB; Q9P7F7; -.
DR PaxDb; Q9P7F7; -.
DR PRIDE; Q9P7F7; -.
DR EnsemblFungi; SPAC1142.07c.1; SPAC1142.07c.1:pep; SPAC1142.07c.
DR GeneID; 2542922; -.
DR KEGG; spo:SPAC1142.07c; -.
DR PomBase; SPAC1142.07c; -.
DR VEuPathDB; FungiDB:SPAC1142.07c; -.
DR eggNOG; KOG1656; Eukaryota.
DR HOGENOM; CLU_071097_1_1_1; -.
DR InParanoid; Q9P7F7; -.
DR OMA; WSWFGGA; -.
DR PhylomeDB; Q9P7F7; -.
DR Reactome; R-SPO-1632852; Macroautophagy.
DR Reactome; R-SPO-917729; Endosomal Sorting Complex Required For Transport (ESCRT).
DR Reactome; R-SPO-9668328; Sealing of the nuclear envelope (NE) by ESCRT-III.
DR PRO; PR:Q9P7F7; -.
DR Proteomes; UP000002485; Chromosome I.
DR GO; GO:0005737; C:cytoplasm; HDA:PomBase.
DR GO; GO:0009898; C:cytoplasmic side of plasma membrane; IBA:GO_Central.
DR GO; GO:0000815; C:ESCRT III complex; ISO:PomBase.
DR GO; GO:0005771; C:multivesicular body; IBA:GO_Central.
DR GO; GO:0045324; P:late endosome to vacuole transport; IMP:PomBase.
DR GO; GO:0032511; P:late endosome to vacuole transport via multivesicular body sorting pathway; IBA:GO_Central.
DR GO; GO:0006998; P:nuclear envelope organization; ISS:PomBase.
DR GO; GO:0043328; P:protein transport to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway; IMP:PomBase.
DR GO; GO:0006900; P:vesicle budding from membrane; IBA:GO_Central.
DR InterPro; IPR005024; Snf7_fam.
DR PANTHER; PTHR22761; PTHR22761; 1.
DR Pfam; PF03357; Snf7; 1.
PE 3: Inferred from homology;
KW Coiled coil; Cytoplasm; Endosome; Membrane; Reference proteome.
FT CHAIN 1..222
FT /note="Vacuolar-sorting protein snf7"
FT /id="PRO_0000211444"
FT REGION 178..222
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 24..111
FT /evidence="ECO:0000255"
FT COILED 150..176
FT /evidence="ECO:0000255"
FT COMPBIAS 202..222
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 222 AA; 25302 MW; 4702F67C8EA54149 CRC64;
MSGFLRWFGG NRSKDTTKDT IVRFQEMLAL YDKKEEVLER QIAEQTEIAR KNATTNKRLA
LTALKRKKMH ENELVKIEGS RNNIEQQLFS IQNANLNFET LQAMRQGAEA MKSIQRGMDA
DKVDQIMDKI RDQQTISEEI STMISTPVGL NAEIDEDELA NELDELQQME LDSKMLGAEK
PPVHTPAVPA VPSQVKDLPS ISKPQELDEE EELRKLQAEF SL
