ID   SNMP1_DROPS             Reviewed;         561 AA.
AC   Q295A8;
DT   03-MAY-2011, integrated into UniProtKB/Swiss-Prot.
DT   14-OCT-2008, sequence version 2.
DT   03-AUG-2022, entry version 64.
DE   RecName: Full=Sensory neuron membrane protein 1 {ECO:0000250|UniProtKB:Q9VDD3};
GN   Name=Snmp1 {ECO:0000250|UniProtKB:Q9VDD3}; ORFNames=GA20018;
OS   Drosophila pseudoobscura pseudoobscura (Fruit fly).
OC   Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC   Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea;
OC   Drosophilidae; Drosophila; Sophophora.
OX   NCBI_TaxID=46245;
RN   [1] {ECO:0000312|EMBL:EAL28804.2}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=MV2-25 / Tucson 14011-0121.94;
RX   PubMed=15632085; DOI=10.1101/gr.3059305;
RA   Richards S., Liu Y., Bettencourt B.R., Hradecky P., Letovsky S.,
RA   Nielsen R., Thornton K., Hubisz M.J., Chen R., Meisel R.P., Couronne O.,
RA   Hua S., Smith M.A., Zhang P., Liu J., Bussemaker H.J., van Batenburg M.F.,
RA   Howells S.L., Scherer S.E., Sodergren E., Matthews B.B., Crosby M.A.,
RA   Schroeder A.J., Ortiz-Barrientos D., Rives C.M., Metzker M.L., Muzny D.M.,
RA   Scott G., Steffen D., Wheeler D.A., Worley K.C., Havlak P., Durbin K.J.,
RA   Egan A., Gill R., Hume J., Morgan M.B., Miner G., Hamilton C., Huang Y.,
RA   Waldron L., Verduzco D., Clerc-Blankenburg K.P., Dubchak I., Noor M.A.F.,
RA   Anderson W., White K.P., Clark A.G., Schaeffer S.W., Gelbart W.M.,
RA   Weinstock G.M., Gibbs R.A.;
RT   "Comparative genome sequencing of Drosophila pseudoobscura: chromosomal,
RT   gene, and cis-element evolution.";
RL   Genome Res. 15:1-18(2005).
CC   -!- FUNCTION: Plays an olfactory role that is not restricted to pheromone
CC       sensitivity. {ECO:0000250|UniProtKB:Q9VDD3}.
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000250|UniProtKB:O02351};
CC       Multi-pass membrane protein {ECO:0000250|UniProtKB:O02351}.
CC   -!- SIMILARITY: Belongs to the CD36 family. {ECO:0000305}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; CM000070; EAL28804.2; -; Genomic_DNA.
DR   RefSeq; XP_001359654.2; XM_001359617.3.
DR   AlphaFoldDB; Q295A8; -.
DR   SMR; Q295A8; -.
DR   STRING; 7237.FBpp0284662; -.
DR   EnsemblMetazoa; FBtr0286224; FBpp0284662; FBgn0080014.
DR   GeneID; 4802810; -.
DR   KEGG; dpo:Dpse_GA20018; -.
DR   eggNOG; KOG3776; Eukaryota.
DR   HOGENOM; CLU_019853_1_2_1; -.
DR   InParanoid; Q295A8; -.
DR   OMA; KFMISKQ; -.
DR   ChiTaRS; Snmp1; fly.
DR   Proteomes; UP000001819; Chromosome 2.
DR   Bgee; FBgn0080014; Expressed in insect adult head and 1 other tissue.
DR   GO; GO:0005929; C:cilium; IEA:EnsemblMetazoa.
DR   GO; GO:0030425; C:dendrite; IEA:EnsemblMetazoa.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0043025; C:neuronal cell body; IEA:EnsemblMetazoa.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0007166; P:cell surface receptor signaling pathway; IEA:EnsemblMetazoa.
DR   GO; GO:0071444; P:cellular response to pheromone; IEA:EnsemblMetazoa.
DR   GO; GO:0050911; P:detection of chemical stimulus involved in sensory perception of smell; IEA:EnsemblMetazoa.
DR   GO; GO:0055088; P:lipid homeostasis; IEA:EnsemblMetazoa.
DR   GO; GO:0035073; P:pupariation; IEA:EnsemblMetazoa.
DR   InterPro; IPR002159; CD36_fam.
DR   PANTHER; PTHR11923; PTHR11923; 1.
DR   Pfam; PF01130; CD36; 1.
DR   PRINTS; PR01609; CD36FAMILY.
PE   3: Inferred from homology;
KW   Cell membrane; Disulfide bond; Glycoprotein; Membrane; Olfaction; Receptor;
KW   Reference proteome; Sensory transduction; Transmembrane;
KW   Transmembrane helix.
FT   CHAIN           1..561
FT                   /note="Sensory neuron membrane protein 1"
FT                   /id="PRO_0000408242"
FT   TOPO_DOM        1..7
FT                   /note="Cytoplasmic"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        8..28
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        29..459
FT                   /note="Extracellular"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        460..480
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        481..561
FT                   /note="Cytoplasmic"
FT                   /evidence="ECO:0000255"
FT   REGION          512..541
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        514..530
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   CARBOHYD        66
FT                   /note="N-linked (GlcNAc...) asparagine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        213
FT                   /note="N-linked (GlcNAc...) asparagine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        226
FT                   /note="N-linked (GlcNAc...) asparagine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        440
FT                   /note="N-linked (GlcNAc...) asparagine"
FT                   /evidence="ECO:0000255"
FT   DISULFID        265..330
FT                   /evidence="ECO:0000250|UniProtKB:P26201"
FT   DISULFID        294..352
FT                   /evidence="ECO:0000250|UniProtKB:P26201"
FT   DISULFID        332..341
FT                   /evidence="ECO:0000250|UniProtKB:P26201"
SQ   SEQUENCE   561 AA;  62712 MW;  014CD7A3ECA66B3F CRC64;
     MKLDRMKLLF VSAGTLVFAI LFGWVMFPKI LKFMISKQVT LKPGTDVREL WSNTPFPLHF
     YFYVFNVTNP EDVSQGGRPR LQEVGPFVFD EWKDKIDLVD DVVEDSVTFT MRNTFIFNAE
     ASYPLTGEET ITLPHPIMQP GGITVQRERA AMMELIAKAM SLVFPGAKAF LSAPFMDLFF
     RGIDVDCSPD DFAAKALCTV FYTGEVKQAK QVNQTHFLFS FMGQANHSDA GRFTVCRGVK
     NNKKLGKVIR FAEETEMDVW PGDECNQFEG TDSTVFPPGL KKEEGLWAFT PDLCRSLGAT
     YVRKSSYHGM PSTRYTLDLG DMRSEEKLHC FCDDPEDLDT CPPRGTMNLA PCVGGPLLAS
     MPHFYNGDPK LVAAVDGLHP NEKDHAVYID FELMSGTPFQ AAKRLQFNLD MEPVEGIEAL
     KNLPKLILPL FWIEEGVHLN KTYTNMVKYT LFLGLKFNSG LRWTLITLSL VGLMSAAYLF
     YQNSDSLDIT LPPKILKEVN KVADAAMNSK MFPEKAPTTP QTTIPGTNPP TNHGAQPPPA
     VASVPGIIPP LSLKMEQAQR Y