ID   SNMP1_PEDHC             Reviewed;         518 AA.
AC   E0W3E3;
DT   03-MAY-2011, integrated into UniProtKB/Swiss-Prot.
DT   02-NOV-2010, sequence version 1.
DT   25-MAY-2022, entry version 41.
DE   RecName: Full=Sensory neuron membrane protein 1 {ECO:0000250|UniProtKB:Q9VDD3};
GN   ORFNames=PHUM603690;
OS   Pediculus humanus subsp. corporis (Body louse).
OC   Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC   Neoptera; Paraneoptera; Psocodea; Phthiraptera; Anoplura; Pediculidae;
OC   Pediculus.
OX   NCBI_TaxID=121224;
RN   [1] {ECO:0000312|EMBL:EEB20149.1}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=USDA;
RX   PubMed=20566863; DOI=10.1073/pnas.1003379107;
RA   Kirkness E.F., Haas B.J., Sun W., Braig H.R., Perotti M.A., Clark J.M.,
RA   Lee S.H., Robertson H.M., Kennedy R.C., Elhaik E., Gerlach D.,
RA   Kriventseva E.V., Elsik C.G., Graur D., Hill C.A., Veenstra J.A.,
RA   Walenz B., Tubio J.M., Ribeiro J.M., Rozas J., Johnston J.S., Reese J.T.,
RA   Popadic A., Tojo M., Raoult D., Reed D.L., Tomoyasu Y., Krause E.,
RA   Mittapalli O., Margam V.M., Li H.M., Meyer J.M., Johnson R.M.,
RA   Romero-Severson J., Vanzee J.P., Alvarez-Ponce D., Vieira F.G., Aguade M.,
RA   Guirao-Rico S., Anzola J.M., Yoon K.S., Strycharz J.P., Unger M.F.,
RA   Christley S., Lobo N.F., Seufferheld M.J., Wang N., Dasch G.A.,
RA   Struchiner C.J., Madey G., Hannick L.I., Bidwell S., Joardar V., Caler E.,
RA   Shao R., Barker S.C., Cameron S., Bruggner R.V., Regier A., Johnson J.,
RA   Viswanathan L., Utterback T.R., Sutton G.G., Lawson D., Waterhouse R.M.,
RA   Venter J.C., Strausberg R.L., Berenbaum M.R., Collins F.H., Zdobnov E.M.,
RA   Pittendrigh B.R.;
RT   "Genome sequences of the human body louse and its primary endosymbiont
RT   provide insights into the permanent parasitic lifestyle.";
RL   Proc. Natl. Acad. Sci. U.S.A. 107:12168-12173(2010).
CC   -!- FUNCTION: Plays an olfactory role that is not restricted to pheromone
CC       sensitivity. {ECO:0000250|UniProtKB:Q9VDD3}.
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000250|UniProtKB:O02351};
CC       Multi-pass membrane protein {ECO:0000250|UniProtKB:O02351}.
CC   -!- SIMILARITY: Belongs to the CD36 family. {ECO:0000305}.
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DR   EMBL; DS235882; EEB20149.1; -; Genomic_DNA.
DR   RefSeq; XP_002432887.1; XM_002432842.1.
DR   AlphaFoldDB; E0W3E3; -.
DR   SMR; E0W3E3; -.
DR   STRING; 121225.PHUM603690-PA; -.
DR   EnsemblMetazoa; PHUM603690-RA; PHUM603690-PA; PHUM603690.
DR   GeneID; 8237028; -.
DR   KEGG; phu:Phum_PHUM603690; -.
DR   CTD; 8237028; -.
DR   VEuPathDB; VectorBase:PHUM603690; -.
DR   eggNOG; KOG3776; Eukaryota.
DR   HOGENOM; CLU_019853_1_2_1; -.
DR   InParanoid; E0W3E3; -.
DR   OMA; KFMISKQ; -.
DR   PhylomeDB; E0W3E3; -.
DR   Proteomes; UP000009046; Unplaced.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0050896; P:response to stimulus; IEA:UniProtKB-KW.
DR   GO; GO:0007608; P:sensory perception of smell; IEA:UniProtKB-KW.
DR   InterPro; IPR002159; CD36_fam.
DR   PANTHER; PTHR11923; PTHR11923; 1.
DR   Pfam; PF01130; CD36; 1.
DR   PRINTS; PR01609; CD36FAMILY.
PE   3: Inferred from homology;
KW   Cell membrane; Disulfide bond; Glycoprotein; Membrane; Olfaction; Receptor;
KW   Reference proteome; Sensory transduction; Transmembrane;
KW   Transmembrane helix.
FT   CHAIN           1..518
FT                   /note="Sensory neuron membrane protein 1"
FT                   /id="PRO_0000408255"
FT   TOPO_DOM        1..8
FT                   /note="Cytoplasmic"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        9..29
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        30..456
FT                   /note="Extracellular"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        457..477
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        478..518
FT                   /note="Cytoplasmic"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        64
FT                   /note="N-linked (GlcNAc...) asparagine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        186
FT                   /note="N-linked (GlcNAc...) asparagine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        225
FT                   /note="N-linked (GlcNAc...) asparagine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        316
FT                   /note="N-linked (GlcNAc...) asparagine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        334
FT                   /note="N-linked (GlcNAc...) asparagine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        381
FT                   /note="N-linked (GlcNAc...) asparagine"
FT                   /evidence="ECO:0000255"
FT   DISULFID        265..330
FT                   /evidence="ECO:0000250|UniProtKB:P26201"
FT   DISULFID        294..349
FT                   /evidence="ECO:0000250|UniProtKB:P26201"
FT   DISULFID        332..338
FT                   /evidence="ECO:0000250|UniProtKB:P26201"
SQ   SEQUENCE   518 AA;  58606 MW;  463EAF1310205BF8 CRC64;
     MKTAEKLGII GTTISIFGIG FGWGVFPWLI RMQIGRVSLS PGSETREFWE KIPFPIDFKI
     HIFNITNHVE VQNEGKIPNL QEIGPYYYKE WKEKSEMIDY ENDDSITFFM KNTWFDNKEK
     TLPLTGDEMV IIPNPILVGL ITAAEREKKG VLPMINKAIP ILFNKPDSVF LKIKVYDLLF
     GGIIFNCTTK DFSASAVCAV LKKEAPFLET VSRSVFKFSI LNQKNGTEEP LKLQIKRGIK
     DYTEVGKVIG ANGKNKLTNW RGRPCNNLEG TDGTIFPSDI SEHQDIWSFN LELCRSIPAK
     FVRKSEYKGI PAFRYNVTIG DTSTDPSLKC LCINDTFCWK KGAMELLKCS GLPVVATLPH
     FYDSHEDFLN GVKGLSPNEE NHSIFFDIEP MTGTPLYAKK RIQFSFPLGK INKIDLTKNL
     PDTLLPFLWV EESIELPDYL IDKLNSELFR ILQFLDVIKW VITLFGAGVV SGGVGLYYKE
     KNSLPITPTS SATSKKIDNP TDKTTTHELG HTNFGYIN