ID   SNMP2_ANOGA             Reviewed;         577 AA.
AC   Q7Q6R1;
DT   25-JAN-2012, integrated into UniProtKB/Swiss-Prot.
DT   25-JAN-2012, sequence version 5.
DT   03-AUG-2022, entry version 92.
DE   RecName: Full=Sensory neuron membrane protein 2 {ECO:0000250|UniProtKB:C3U0S3};
GN   Name=SCRB16 {ECO:0000312|EMBL:EAA11629.4}; ORFNames=AGAP005716;
OS   Anopheles gambiae (African malaria mosquito).
OC   Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC   Neoptera; Endopterygota; Diptera; Nematocera; Culicoidea; Culicidae;
OC   Anophelinae; Anopheles.
OX   NCBI_TaxID=7165;
RN   [1] {ECO:0000312|EMBL:EAA11629.4}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=PEST;
RX   PubMed=12364791; DOI=10.1126/science.1076181;
RA   Holt R.A., Subramanian G.M., Halpern A., Sutton G.G., Charlab R.,
RA   Nusskern D.R., Wincker P., Clark A.G., Ribeiro J.M.C., Wides R.,
RA   Salzberg S.L., Loftus B.J., Yandell M.D., Majoros W.H., Rusch D.B., Lai Z.,
RA   Kraft C.L., Abril J.F., Anthouard V., Arensburger P., Atkinson P.W.,
RA   Baden H., de Berardinis V., Baldwin D., Benes V., Biedler J., Blass C.,
RA   Bolanos R., Boscus D., Barnstead M., Cai S., Center A., Chaturverdi K.,
RA   Christophides G.K., Chrystal M.A.M., Clamp M., Cravchik A., Curwen V.,
RA   Dana A., Delcher A., Dew I., Evans C.A., Flanigan M.,
RA   Grundschober-Freimoser A., Friedli L., Gu Z., Guan P., Guigo R.,
RA   Hillenmeyer M.E., Hladun S.L., Hogan J.R., Hong Y.S., Hoover J.,
RA   Jaillon O., Ke Z., Kodira C.D., Kokoza E., Koutsos A., Letunic I.,
RA   Levitsky A.A., Liang Y., Lin J.-J., Lobo N.F., Lopez J.R., Malek J.A.,
RA   McIntosh T.C., Meister S., Miller J.R., Mobarry C., Mongin E., Murphy S.D.,
RA   O'Brochta D.A., Pfannkoch C., Qi R., Regier M.A., Remington K., Shao H.,
RA   Sharakhova M.V., Sitter C.D., Shetty J., Smith T.J., Strong R., Sun J.,
RA   Thomasova D., Ton L.Q., Topalis P., Tu Z.J., Unger M.F., Walenz B.,
RA   Wang A.H., Wang J., Wang M., Wang X., Woodford K.J., Wortman J.R., Wu M.,
RA   Yao A., Zdobnov E.M., Zhang H., Zhao Q., Zhao S., Zhu S.C., Zhimulev I.,
RA   Coluzzi M., della Torre A., Roth C.W., Louis C., Kalush F., Mural R.J.,
RA   Myers E.W., Adams M.D., Smith H.O., Broder S., Gardner M.J., Fraser C.M.,
RA   Birney E., Bork P., Brey P.T., Venter J.C., Weissenbach J., Kafatos F.C.,
RA   Collins F.H., Hoffman S.L.;
RT   "The genome sequence of the malaria mosquito Anopheles gambiae.";
RL   Science 298:129-149(2002).
RN   [2] {ECO:0000305}
RP   IDENTIFICATION.
RX   PubMed=18342246; DOI=10.1016/j.ibmb.2007.11.003;
RA   Nichols Z., Vogt R.G.;
RT   "The SNMP/CD36 gene family in Diptera, Hymenoptera and Coleoptera:
RT   Drosophila melanogaster, D. pseudoobscura, Anopheles gambiae, Aedes
RT   aegypti, Apis mellifera, and Tribolium castaneum.";
RL   Insect Biochem. Mol. Biol. 38:398-415(2008).
CC   -!- FUNCTION: Plays an olfactory role that is not restricted to pheromone
CC       sensitivity. {ECO:0000250|UniProtKB:O02351}.
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000250|UniProtKB:O02351};
CC       Multi-pass membrane protein {ECO:0000250|UniProtKB:O02351}.
CC   -!- SIMILARITY: Belongs to the CD36 family. {ECO:0000255}.
CC   -!- SEQUENCE CAUTION:
CC       Sequence=EAA11629.4; Type=Erroneous gene model prediction; Evidence={ECO:0000305};
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DR   EMBL; AAAB01008960; EAA11629.4; ALT_SEQ; Genomic_DNA.
DR   RefSeq; XP_315733.4; XM_315733.4.
DR   AlphaFoldDB; Q7Q6R1; -.
DR   SMR; Q7Q6R1; -.
DR   STRING; 7165.AGAP005716-PA; -.
DR   PRIDE; Q7Q6R1; -.
DR   GeneID; 1276390; -.
DR   KEGG; aga:AgaP_AGAP005716; -.
DR   CTD; 1276390; -.
DR   VEuPathDB; VectorBase:AGAP005716; -.
DR   eggNOG; KOG3776; Eukaryota.
DR   HOGENOM; CLU_019853_1_2_1; -.
DR   InParanoid; Q7Q6R1; -.
DR   OrthoDB; 1106566at2759; -.
DR   Proteomes; UP000007062; Chromosome 2L.
DR   GO; GO:0005737; C:cytoplasm; IBA:GO_Central.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0005044; F:scavenger receptor activity; IBA:GO_Central.
DR   GO; GO:0050896; P:response to stimulus; IEA:UniProtKB-KW.
DR   GO; GO:0007608; P:sensory perception of smell; IEA:UniProtKB-KW.
DR   InterPro; IPR002159; CD36_fam.
DR   PANTHER; PTHR11923; PTHR11923; 1.
DR   Pfam; PF01130; CD36; 1.
DR   PRINTS; PR01609; CD36FAMILY.
PE   3: Inferred from homology;
KW   Cell membrane; Disulfide bond; Glycoprotein; Membrane; Olfaction; Receptor;
KW   Reference proteome; Sensory transduction; Transmembrane;
KW   Transmembrane helix.
FT   CHAIN           1..577
FT                   /note="Sensory neuron membrane protein 2"
FT                   /id="PRO_0000414927"
FT   TOPO_DOM        1..6
FT                   /note="Cytoplasmic"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        7..27
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        28..519
FT                   /note="Extracellular"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        520..540
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        541..577
FT                   /note="Cytoplasmic"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        66
FT                   /note="N-linked (GlcNAc...) asparagine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        161
FT                   /note="N-linked (GlcNAc...) asparagine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        271
FT                   /note="N-linked (GlcNAc...) asparagine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        307
FT                   /note="N-linked (GlcNAc...) asparagine"
FT                   /evidence="ECO:0000255"
FT   DISULFID        316..384
FT                   /evidence="ECO:0000250|UniProtKB:P26201"
FT   DISULFID        345..411
FT                   /evidence="ECO:0000250|UniProtKB:P26201"
FT   DISULFID        386..400
FT                   /evidence="ECO:0000250|UniProtKB:P26201"
SQ   SEQUENCE   577 AA;  65174 MW;  80C93A10F845CBE1 CRC64;
     MVQCTLIWAG IGAMMAVSGA LLGWVVFPRA VHEKVIEATE LRQGTDQYKR WEALPQPLDF
     KVYIFNVTNP YEVMQGRRPK VVEVGPYVYF QYRQKDNVRF SRDRSKVHFS QQQMYVFDAE
     SSYPLTENDE LTVLNMHMNS ILQIIDNQAK ETITNFRSDV NNTLEKIPVV RVIKRIIERT
     TPIQSILQLA EDETYDSLRL INVELNRIFG RPDTMFLRTT PKQFLFDGVP FCVNVIGIAK
     AICKEIEKRN TKTIRTMPDG SLRFSFFSHK NMTDDGMFTI NTGIKDPSRT QMIELWNGRT
     TLDVWNNRSS GLSSSCNKIH GTDGSGYPPF RTGVERMTIF STDICRTVDI KLTGSSSYEG
     IPALRYEIDN NFLHEIGPEY GNDCYCVNKI PKSIVKSNGC LYKGALDLSN CFDAPVVLTL
     PHMLGVAEEY TALIDGMDPE PERHQIFVDV EPYTGTPLNG GKRVQFNMFL RRIDAIKLTD
     RLQPTLFPVI WIDEGIALNE DMVKLIDDSL MKVLSLLDVV QWVLIGVGLL LAVLMPTVYF
     VKRCRGEGSR TVSPAVTATT SAASLSTVAG VTGDRSK