SNP47_DANRE
ID SNP47_DANRE Reviewed; 419 AA.
AC Q0P4A7;
DT 23-OCT-2007, integrated into UniProtKB/Swiss-Prot.
DT 19-SEP-2006, sequence version 1.
DT 03-AUG-2022, entry version 83.
DE RecName: Full=Synaptosomal-associated protein 47;
DE Short=SNAP-47;
DE AltName: Full=Synaptosomal-associated 47 kDa protein;
GN Name=snap47; ORFNames=zgc:153222;
OS Danio rerio (Zebrafish) (Brachydanio rerio).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes;
OC Danionidae; Danioninae; Danio.
OX NCBI_TaxID=7955;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC TISSUE=Embryo;
RG NIH - Zebrafish Gene Collection (ZGC) project;
RL Submitted (AUG-2006) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: May play a role in intracellular membrane fusion.
CC {ECO:0000250}.
CC -!- SIMILARITY: Belongs to the SVAP1 family. {ECO:0000305}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; BC122195; AAI22196.1; -; mRNA.
DR RefSeq; NP_001038902.1; NM_001045437.1.
DR AlphaFoldDB; Q0P4A7; -.
DR SMR; Q0P4A7; -.
DR STRING; 7955.ENSDARP00000106830; -.
DR PaxDb; Q0P4A7; -.
DR Ensembl; ENSDART00000092741; ENSDARP00000087173; ENSDARG00000063445.
DR GeneID; 751727; -.
DR KEGG; dre:751727; -.
DR CTD; 116841; -.
DR ZFIN; ZDB-GENE-060825-140; snap47.
DR eggNOG; KOG3065; Eukaryota.
DR GeneTree; ENSGT00950000182843; -.
DR HOGENOM; CLU_029855_0_0_1; -.
DR InParanoid; Q0P4A7; -.
DR OMA; FDNMMQG; -.
DR OrthoDB; 662135at2759; -.
DR PhylomeDB; Q0P4A7; -.
DR TreeFam; TF331066; -.
DR PRO; PR:Q0P4A7; -.
DR Proteomes; UP000000437; Genome assembly.
DR Proteomes; UP000814640; Chromosome 2.
DR Bgee; ENSDARG00000063445; Expressed in brain and 22 other tissues.
DR ExpressionAtlas; Q0P4A7; baseline and differential.
DR GO; GO:0005886; C:plasma membrane; IBA:GO_Central.
DR GO; GO:0098793; C:presynapse; IEA:GOC.
DR GO; GO:0031201; C:SNARE complex; IBA:GO_Central.
DR GO; GO:0005484; F:SNAP receptor activity; IBA:GO_Central.
DR GO; GO:0019905; F:syntaxin binding; IBA:GO_Central.
DR GO; GO:0006887; P:exocytosis; IBA:GO_Central.
DR GO; GO:0031629; P:synaptic vesicle fusion to presynaptic active zone membrane; IBA:GO_Central.
DR GO; GO:0016082; P:synaptic vesicle priming; IBA:GO_Central.
DR GO; GO:0006906; P:vesicle fusion; IBA:GO_Central.
DR Gene3D; 2.30.29.30; -; 1.
DR InterPro; IPR011993; PH-like_dom_sf.
DR InterPro; IPR000727; T_SNARE_dom.
DR PROSITE; PS50192; T_SNARE; 2.
PE 2: Evidence at transcript level;
KW Coiled coil; Reference proteome; Repeat.
FT CHAIN 1..419
FT /note="Synaptosomal-associated protein 47"
FT /id="PRO_0000307154"
FT DOMAIN 108..170
FT /note="t-SNARE coiled-coil homology 1"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00202"
FT DOMAIN 356..418
FT /note="t-SNARE coiled-coil homology 2"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00202"
SQ SEQUENCE 419 AA; 47191 MW; A4CEBA3BEA0BD2BA CRC64;
MSQEPSIHTW PGSYYINSEK RWASGVLSLS RTTLRFASEQ KQESLMSLKL SRIMEIKMES
SSIIFSALTV LEQGNLKHWF GSLRPCRNAV YHVLEHFWRE RLLSPSEPQG AEAPLSKGQE
LISLISGAQR RLEDTGKVLN HQGEQFDNMI QGLDKIESDL TVADKLLSEL ECPSWWPFSK
MPWRSHQEAK SEAAAKAACT KGSGKIQKVI VSIPAIVFRD GNTGNMKPGS LTLLVSSLEV
REANGQLLHC FEKEEVDDIH VFNPYEISIR QRFIGKPDIC FRLLSARMTE ALSVLEMQYK
KKVEVTRDYA VFRSTSATTP ESPESGGNVW AAGHGQDTEV PVEVPAGELT QLQLQVLQPT
VTEAEAQELK QMLQQLKNLA LEAETELERQ DEALDVLSCS TDHATMNINR HTRRMRKLL