ID   SNPC3_BOVIN             Reviewed;         412 AA.
AC   Q5E9M5;
DT   25-OCT-2005, integrated into UniProtKB/Swiss-Prot.
DT   15-MAR-2005, sequence version 1.
DT   25-MAY-2022, entry version 57.
DE   RecName: Full=snRNA-activating protein complex subunit 3;
DE            Short=SNAPc subunit 3;
DE   AltName: Full=Small nuclear RNA-activating complex polypeptide 3;
GN   Name=SNAPC3;
OS   Bos taurus (Bovine).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae;
OC   Bovinae; Bos.
OX   NCBI_TaxID=9913;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RX   PubMed=16305752; DOI=10.1186/1471-2164-6-166;
RA   Harhay G.P., Sonstegard T.S., Keele J.W., Heaton M.P., Clawson M.L.,
RA   Snelling W.M., Wiedmann R.T., Van Tassell C.P., Smith T.P.L.;
RT   "Characterization of 954 bovine full-CDS cDNA sequences.";
RL   BMC Genomics 6:166-166(2005).
CC   -!- FUNCTION: Part of the SNAPc complex required for the transcription of
CC       both RNA polymerase II and III small-nuclear RNA genes. Binds to the
CC       proximal sequence element (PSE), a non-TATA-box basal promoter element
CC       common to these 2 types of genes. Recruits TBP and BRF2 to the U6 snRNA
CC       TATA box (By similarity). {ECO:0000250}.
CC   -!- SUBUNIT: Part of the SNAPc complex composed of 5 subunits: SNAPC1,
CC       SNAPC2, SNAPC3, SNAPC4 and SNAPC5. SNAPC3 interacts with SNAPC1 (By
CC       similarity). {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the SNAPC3/SRD2 family. {ECO:0000305}.
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DR   EMBL; BT020895; AAX08912.1; -; mRNA.
DR   AlphaFoldDB; Q5E9M5; -.
DR   InParanoid; Q5E9M5; -.
DR   OrthoDB; 1595999at2759; -.
DR   Proteomes; UP000009136; Unplaced.
DR   GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR   GO; GO:0019185; C:snRNA-activating protein complex; IBA:GO_Central.
DR   GO; GO:0003681; F:bent DNA binding; IBA:GO_Central.
DR   GO; GO:0001006; F:RNA polymerase III type 3 promoter sequence-specific DNA binding; IBA:GO_Central.
DR   GO; GO:0042795; P:snRNA transcription by RNA polymerase II; IBA:GO_Central.
DR   GO; GO:0042796; P:snRNA transcription by RNA polymerase III; IBA:GO_Central.
DR   InterPro; IPR022042; snRNA-activating_su3.
DR   PANTHER; PTHR13421; PTHR13421; 1.
DR   Pfam; PF12251; SNAPC3; 1.
PE   2: Evidence at transcript level;
KW   DNA-binding; Nucleus; Reference proteome; Transcription;
KW   Transcription regulation.
FT   CHAIN           1..412
FT                   /note="snRNA-activating protein complex subunit 3"
FT                   /id="PRO_0000072023"
FT   REGION          1..28
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   412 AA;  46961 MW;  531D7B607D4354C7 CRC64;
     MAEGSRGGPA CGRMEDRQDP APSSGGCGFP EYELPELNTR AFHVGAFGEL WRCRLRGKGD
     LSLKEPPAPA VPEGDTVADS GREDAAVARD LGCSLEAAAE LRAVCGLDKL KCLEEGEDPE
     VIPENTDLVT LGVRKRLLEH RKETITIDRV CRQETFAYEM ESHAMGKKPE NPADMIEEGE
     LILSVNILYP VIFHKHKEHK PYQTILVLGS QKLTELRDAI CCVSDLQIGG EFSNTPDQAP
     EHISKDLYKS AFFYFEGTFY NDKRYPECRD LSRTIIEWSE SHDRGYGKFQ TAKMEDFTFN
     DLYIKLGFPY LYCHQGDCEH VVVITDIRLV HHDDCLDRTL YPLLIKKHWL WTRKCFVCKM
     YTARWVTNND SFAPEDPCFF CDVCFRMLHY DSEGNKLGEF LAYPYVDPGT FN