SNPC3_MACFA
ID SNPC3_MACFA Reviewed; 412 AA.
AC Q4R6Y6;
DT 25-OCT-2005, integrated into UniProtKB/Swiss-Prot.
DT 19-JUL-2005, sequence version 1.
DT 03-AUG-2022, entry version 53.
DE RecName: Full=snRNA-activating protein complex subunit 3;
DE Short=SNAPc subunit 3;
DE AltName: Full=Small nuclear RNA-activating complex polypeptide 3;
GN Name=SNAPC3; ORFNames=QtsA-16848;
OS Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini;
OC Cercopithecidae; Cercopithecinae; Macaca.
OX NCBI_TaxID=9541;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC TISSUE=Testis;
RG International consortium for macaque cDNA sequencing and analysis;
RT "DNA sequences of macaque genes expressed in brain or testis and its
RT evolutionary implications.";
RL Submitted (JUN-2005) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Part of the SNAPc complex required for the transcription of
CC both RNA polymerase II and III small-nuclear RNA genes. Binds to the
CC proximal sequence element (PSE), a non-TATA-box basal promoter element
CC common to these 2 types of genes. Recruits TBP and BRF2 to the U6 snRNA
CC TATA box (By similarity). {ECO:0000250}.
CC -!- SUBUNIT: Part of the SNAPc complex composed of 5 subunits: SNAPC1,
CC SNAPC2, SNAPC3, SNAPC4 and SNAPC5. SNAPC3 interacts with SNAPC1 (By
CC similarity). {ECO:0000250}.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000250}.
CC -!- SIMILARITY: Belongs to the SNAPC3/SRD2 family. {ECO:0000305}.
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DR EMBL; AB169044; BAE01138.1; -; mRNA.
DR RefSeq; NP_001271806.1; NM_001284877.1.
DR RefSeq; XP_015291968.1; XM_015436482.1.
DR AlphaFoldDB; Q4R6Y6; -.
DR STRING; 9541.XP_005581741.1; -.
DR GeneID; 101865660; -.
DR CTD; 6619; -.
DR VEuPathDB; HostDB:ENSMFAG00000039519; -.
DR eggNOG; KOG2664; Eukaryota.
DR OMA; WSEAHDR; -.
DR OrthoDB; 1595999at2759; -.
DR Proteomes; UP000233100; Chromosome 15.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR InterPro; IPR022042; snRNA-activating_su3.
DR PANTHER; PTHR13421; PTHR13421; 1.
DR Pfam; PF12251; SNAPC3; 1.
PE 2: Evidence at transcript level;
KW DNA-binding; Nucleus; Reference proteome; Transcription;
KW Transcription regulation.
FT CHAIN 1..412
FT /note="snRNA-activating protein complex subunit 3"
FT /id="PRO_0000072025"
FT REGION 1..22
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 412 AA; 46937 MW; C314E4AC3DADA444 CRC64;
MAEGSRGVPT CSGVAGRQDP VSGSGGCNFP EYELPELNTR AFHVGAFGEL WRGRLRGAGD
LSLREPPASA LPGSRGIADS DREDAAVARD LDCSLEAAAE LRAVCGLDKL KCLEDGEDPE
VIPENTDLVT LGVRKRFLEH REETITIDRA CRQETFVYEM ESHAIGKKPE NSADMIEEGE
LILSVNILYP VIFHKHKEHK PYQTMLVLGS QKLTELRDSI RCVSDLQIGG EFSNTPDQAP
EHISKDLYKS AFFYFEGTFY NDKRYPECRD LSRTIIEWSE SHDRGYGKFQ TARMEDFTFN
DLCIKLGFPY LYCHQGDCEH VIVITDIRLV HHDDCLDRTL YPLLIKKHWL WTRKCFVCKM
YTARWVTNND SFAPEDPCFF CDVCFRMLHY DSEGNKLGEF LAYPYVDPGT FN