ID   SNPC3_RAT               Reviewed;         407 AA.
AC   Q5BK68;
DT   25-OCT-2005, integrated into UniProtKB/Swiss-Prot.
DT   12-APR-2005, sequence version 1.
DT   03-AUG-2022, entry version 99.
DE   RecName: Full=snRNA-activating protein complex subunit 3;
DE            Short=SNAPc subunit 3;
DE   AltName: Full=Small nuclear RNA-activating complex polypeptide 3;
GN   Name=Snapc3;
OS   Rattus norvegicus (Rat).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae;
OC   Murinae; Rattus.
OX   NCBI_TaxID=10116;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   TISSUE=Spleen;
RX   PubMed=15489334; DOI=10.1101/gr.2596504;
RG   The MGC Project Team;
RT   "The status, quality, and expansion of the NIH full-length cDNA project:
RT   the Mammalian Gene Collection (MGC).";
RL   Genome Res. 14:2121-2127(2004).
CC   -!- FUNCTION: Part of the SNAPc complex required for the transcription of
CC       both RNA polymerase II and III small-nuclear RNA genes. Binds to the
CC       proximal sequence element (PSE), a non-TATA-box basal promoter element
CC       common to these 2 types of genes. Recruits TBP and BRF2 to the U6 snRNA
CC       TATA box (By similarity). {ECO:0000250}.
CC   -!- SUBUNIT: Part of the SNAPc complex composed of 5 subunits: SNAPC1,
CC       SNAPC2, SNAPC3, SNAPC4 and SNAPC5. SNAPC3 interacts with SNAPC1 (By
CC       similarity). {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the SNAPC3/SRD2 family. {ECO:0000305}.
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DR   EMBL; BC091186; AAH91186.1; -; mRNA.
DR   RefSeq; NP_001013230.1; NM_001013212.1.
DR   AlphaFoldDB; Q5BK68; -.
DR   STRING; 10116.ENSRNOP00000015254; -.
DR   PaxDb; Q5BK68; -.
DR   Ensembl; ENSRNOT00000015254; ENSRNOP00000015254; ENSRNOG00000010825.
DR   GeneID; 362537; -.
DR   KEGG; rno:362537; -.
DR   UCSC; RGD:1305172; rat.
DR   CTD; 6619; -.
DR   RGD; 1305172; Snapc3.
DR   eggNOG; KOG2664; Eukaryota.
DR   GeneTree; ENSGT00390000005708; -.
DR   HOGENOM; CLU_041861_0_1_1; -.
DR   InParanoid; Q5BK68; -.
DR   OMA; WSEAHDR; -.
DR   OrthoDB; 1595999at2759; -.
DR   PhylomeDB; Q5BK68; -.
DR   TreeFam; TF317705; -.
DR   Reactome; R-RNO-6807505; RNA polymerase II transcribes snRNA genes.
DR   Reactome; R-RNO-76071; RNA Polymerase III Transcription Initiation From Type 3 Promoter.
DR   PRO; PR:Q5BK68; -.
DR   Proteomes; UP000002494; Chromosome 5.
DR   Bgee; ENSRNOG00000010825; Expressed in ovary and 19 other tissues.
DR   Genevisible; Q5BK68; RN.
DR   GO; GO:0016604; C:nuclear body; IEA:Ensembl.
DR   GO; GO:0005730; C:nucleolus; IEA:Ensembl.
DR   GO; GO:0019185; C:snRNA-activating protein complex; IBA:GO_Central.
DR   GO; GO:0003681; F:bent DNA binding; IBA:GO_Central.
DR   GO; GO:0001006; F:RNA polymerase III type 3 promoter sequence-specific DNA binding; IBA:GO_Central.
DR   GO; GO:0042795; P:snRNA transcription by RNA polymerase II; IBA:GO_Central.
DR   GO; GO:0042796; P:snRNA transcription by RNA polymerase III; IBA:GO_Central.
DR   InterPro; IPR022042; snRNA-activating_su3.
DR   PANTHER; PTHR13421; PTHR13421; 1.
DR   Pfam; PF12251; SNAPC3; 1.
PE   2: Evidence at transcript level;
KW   DNA-binding; Nucleus; Reference proteome; Transcription;
KW   Transcription regulation.
FT   CHAIN           1..407
FT                   /note="snRNA-activating protein complex subunit 3"
FT                   /id="PRO_0000072027"
FT   REGION          1..26
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   407 AA;  46230 MW;  6721A38C1D480A58 CRC64;
     MAEDPQGGGA GGPQHPVPSG SHSSFPEYEL PELHTRVFHV GAFGELWRGR LGAQDLSLNE
     PQAAAQPTDG EASNNGFEDA AVAEDLGCSL EAAAELRVVC GLDKLRCLGE DEDPEVIPEN
     TDLVTLCVRK GLLDYREENI TIDRACRQET FAYEMESHAL GKKPENPADM IEEGESILSV
     NILYPVIFNK HREHKPYQTV LVLGSQKLTE LRDSICCVSD LQIGGEFSNA PDQAPEHISK
     DLYKSAFFYF EGTFYNDKRY PECRDLSRTI IEWSESHDRG YGKFQTARME DFTFNDLNIK
     LGFPYLYCHQ GDCEHVVVIT DIRLVHHDDC LDRTLYPLLT KKHWLWTRKC FVCKMYTARW
     VTNNDTFAPE DPCFFCDVCF RMLHYDSEGN KLGEFLAYPY VDPGTFN