SNPF1_DELRA
ID SNPF1_DELRA Reviewed; 11 AA.
AC B3EWL7; B3EWL6;
DT 03-OCT-2012, integrated into UniProtKB/Swiss-Prot.
DT 03-OCT-2012, sequence version 1.
DT 02-JUN-2021, entry version 10.
DE RecName: Full=Short neuropeptide F-1 {ECO:0000303|PubMed:22848525};
DE Short=sNPF-1 {ECO:0000303|PubMed:22848525};
DE AltName: Full=RLRF-amide {ECO:0000303|PubMed:20869420};
DE Contains:
DE RecName: Full=Short neuropeptide F-1(4-11) {ECO:0000303|PubMed:22848525};
DE Short=sNPF-1(4-11) {ECO:0000303|PubMed:22848525};
DE AltName: Full=RLRF-amide(4-11) {ECO:0000303|PubMed:20869420};
OS Delia radicum (Cabbage root fly) (Anthomyia brassicae).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Muscoidea;
OC Anthomyiidae; Anthomyiinae; Delia.
OX NCBI_TaxID=30064;
RN [1] {ECO:0000305}
RP PROTEIN SEQUENCE, TISSUE SPECIFICITY, MASS SPECTROMETRY, AND AMIDATION AT
RP PHE-11.
RC TISSUE=Abdominal ganglion {ECO:0000269|PubMed:20869420},
RC Brain {ECO:0000269|PubMed:20869420},
RC Corpora allata {ECO:0000269|PubMed:20869420}, and
RC Corpora cardiaca {ECO:0000269|PubMed:20869420};
RX PubMed=20869420; DOI=10.1016/j.peptides.2010.08.028;
RA Audsley N., Matthews H.J., Down R.E., Weaver R.J.;
RT "Neuropeptides associated with the central nervous system of the cabbage
RT root fly, Delia radicum (L).";
RL Peptides 32:434-440(2011).
RN [2] {ECO:0000305}
RP PROTEIN SEQUENCE, TISSUE SPECIFICITY, DEVELOPMENTAL STAGE, MASS
RP SPECTROMETRY, AND AMIDATION AT PHE-11.
RC TISSUE=CNS {ECO:0000269|PubMed:22848525}, and
RC Ring ganglion {ECO:0000269|PubMed:22848525};
RX PubMed=22848525; DOI=10.1371/journal.pone.0041543;
RA Zoephel J., Reiher W., Rexer K.-H., Kahnt J., Wegener C.;
RT "Peptidomics of the agriculturally damaging larval stage of the cabbage
RT root fly Delia radicum (Diptera: Anthomyiidae).";
RL PLoS ONE 7:E41543-E41543(2012).
CC -!- SUBCELLULAR LOCATION: Secreted {ECO:0000250|UniProtKB:Q9VIQ0}.
CC -!- TISSUE SPECIFICITY: In larvae, both sNPF-1 and sNPF-1(4-11) are
CC expressed in the CNS and ring gland but not the midgut or thoracic
CC perisympathetic organs (tPSO) and abdominal perisympathetic organs
CC (aPSO) (at protein level). In adults, both sNPF-1 and sNPF-1(4-11) are
CC expressed in brain, cardiaca, corpora allata and thoracic-abdominal
CC ganglion (at protein level). {ECO:0000269|PubMed:20869420,
CC ECO:0000269|PubMed:22848525}.
CC -!- DEVELOPMENTAL STAGE: Detected in larvae and adults.
CC {ECO:0000269|PubMed:20869420, ECO:0000269|PubMed:22848525}.
CC -!- MASS SPECTROMETRY: [Short neuropeptide F-1]: Mass=1329.7; Method=MALDI;
CC Evidence={ECO:0000269|PubMed:20869420, ECO:0000269|PubMed:22848525};
CC -!- MASS SPECTROMETRY: [Short neuropeptide F-1]: Mass=1329.80;
CC Method=MALDI; Evidence={ECO:0000269|PubMed:20869420,
CC ECO:0000269|PubMed:22848525};
CC -!- SIMILARITY: Belongs to the NPY family. {ECO:0000255}.
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DR GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR GO; GO:0007218; P:neuropeptide signaling pathway; IEA:UniProtKB-KW.
PE 1: Evidence at protein level;
KW Amidation; Direct protein sequencing; Neuropeptide; Secreted.
FT PEPTIDE 1..11
FT /note="Short neuropeptide F-1"
FT /evidence="ECO:0000269|PubMed:20869420,
FT ECO:0000269|PubMed:22848525"
FT /id="PRO_0000419737"
FT PEPTIDE 1..11
FT /note="Short neuropeptide F-1(4-11)"
FT /evidence="ECO:0000269|PubMed:20869420,
FT ECO:0000269|PubMed:22848525"
FT /id="PRO_0000419738"
FT MOD_RES 11
FT /note="Phenylalanine amide"
FT /evidence="ECO:0000269|PubMed:20869420,
FT ECO:0000269|PubMed:22848525"
FT UNSURE 7
FT /note="L or I"
FT /evidence="ECO:0000269|PubMed:22848525"
FT UNSURE 9
FT /note="L or I"
FT /evidence="ECO:0000269|PubMed:22848525"
SQ SEQUENCE 11 AA; 1331 MW; 810A02310735A775 CRC64;
AQRSPSLRLR F