SNR27_DANRE
ID SNR27_DANRE Reviewed; 158 AA.
AC Q6DH74;
DT 21-FEB-2006, integrated into UniProtKB/Swiss-Prot.
DT 16-AUG-2004, sequence version 1.
DT 03-AUG-2022, entry version 91.
DE RecName: Full=U4/U6.U5 small nuclear ribonucleoprotein 27 kDa protein;
DE Short=U4/U6.U5 snRNP 27 kDa protein;
DE Short=U4/U6.U5-27K;
DE AltName: Full=U4/U6.U5 tri-snRNP-associated protein 3;
GN Name=snrnp27; ORFNames=zgc:92615;
OS Danio rerio (Zebrafish) (Brachydanio rerio).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes;
OC Danionidae; Danioninae; Danio.
OX NCBI_TaxID=7955;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC TISSUE=Brain;
RG NIH - Zebrafish Gene Collection (ZGC) project;
RL Submitted (JUL-2004) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: May play a role in mRNA splicing. {ECO:0000250}.
CC -!- SUBUNIT: Part of a tri-snRNP complex. {ECO:0000250}.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000305}.
CC -!- SIMILARITY: Belongs to the SNUT3 family. {ECO:0000305}.
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DR EMBL; BC076105; AAH76105.1; -; mRNA.
DR RefSeq; NP_001002703.1; NM_001002703.2.
DR AlphaFoldDB; Q6DH74; -.
DR SMR; Q6DH74; -.
DR STRING; 7955.ENSDARP00000051654; -.
DR PaxDb; Q6DH74; -.
DR Ensembl; ENSDART00000051655; ENSDARP00000051654; ENSDARG00000035625.
DR GeneID; 436976; -.
DR KEGG; dre:436976; -.
DR CTD; 11017; -.
DR ZFIN; ZDB-GENE-040718-457; snrnp27.
DR eggNOG; KOG3263; Eukaryota.
DR GeneTree; ENSGT00730000111237; -.
DR HOGENOM; CLU_075596_2_1_1; -.
DR InParanoid; Q6DH74; -.
DR OMA; SMKRKYR; -.
DR OrthoDB; 1627375at2759; -.
DR TreeFam; TF314458; -.
DR Reactome; R-DRE-72163; mRNA Splicing - Major Pathway.
DR PRO; PR:Q6DH74; -.
DR Proteomes; UP000000437; Genome assembly.
DR Proteomes; UP000814640; Chromosome 5.
DR Bgee; ENSDARG00000035625; Expressed in early embryo and 29 other tissues.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.
DR GO; GO:0008380; P:RNA splicing; IEA:UniProtKB-KW.
DR InterPro; IPR013957; SNRNP27.
DR Pfam; PF08648; SNRNP27; 1.
PE 2: Evidence at transcript level;
KW mRNA processing; mRNA splicing; Nucleus; Reference proteome.
FT CHAIN 1..158
FT /note="U4/U6.U5 small nuclear ribonucleoprotein 27 kDa
FT protein"
FT /id="PRO_0000223967"
FT REGION 1..100
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1..15
FT /note="Basic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 16..39
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 40..64
FT /note="Basic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 65..100
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 158 AA; 19131 MW; 9813A8C1CCCA42AD CRC64;
MGRSRSRTPP RRERRRSRSS SRDRERRRRE RERSRSRDRD RRRSRSRSPH RRRSRSPRRH
RSSSLSPLRQ KDRRDDDRKD VKEKPAKVHQ ISAEDMQGKT EEEIEMMKLM GFGSFETSKG
KKKDGSIKAF AVNVSQKRKY RQYMNRKGGF NRPLDFIA