ID   SNTAN_BOVIN             Reviewed;         147 AA.
AC   Q0P561; B7FF68;
DT   01-JUL-2008, integrated into UniProtKB/Swiss-Prot.
DT   19-SEP-2006, sequence version 1.
DT   03-AUG-2022, entry version 75.
DE   RecName: Full=Sentan;
DE   AltName: Full=Protein S100-A1-like;
DE   AltName: Full=S100 calcium-binding protein A1-like;
GN   Name=SNTN; Synonyms=S100A1L;
OS   Bos taurus (Bovine).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae;
OC   Bovinae; Bos.
OX   NCBI_TaxID=9913;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   STRAIN=Crossbred X Angus; TISSUE=Liver;
RG   NIH - Mammalian Gene Collection (MGC) project;
RL   Submitted (AUG-2006) to the EMBL/GenBank/DDBJ databases.
RN   [2]
RP   IDENTIFICATION.
RX   PubMed=18829862; DOI=10.1091/mbc.e08-07-0691;
RA   Kubo A., Yuba-Kubo A., Tsukita S., Tsukita S., Amagai M.;
RT   "Sentan: a novel specific component of the apical structure of vertebrate
RT   motile cilia.";
RL   Mol. Biol. Cell 19:5338-5346(2008).
CC   -!- FUNCTION: May be a component of the linker structure that bridges the
CC       ciliary membrane and peripheral singlet microtubules. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Cell projection, cilium {ECO:0000250}.
CC       Note=Expressed exclusively at the cilium tip where it localizes between
CC       the cell membrane and peripheral A-subfibers. {ECO:0000250}.
CC   -!- MISCELLANEOUS: 'Sentan' means 'tip' in Japanese.
CC   -!- SIMILARITY: Belongs to the S-100 family. {ECO:0000305}.
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DR   EMBL; BC120476; AAI20477.1; -; mRNA.
DR   EMBL; BR000726; FAA00432.1; -; mRNA.
DR   RefSeq; NP_001071606.1; NM_001078138.2.
DR   AlphaFoldDB; Q0P561; -.
DR   SMR; Q0P561; -.
DR   STRING; 9913.ENSBTAP00000017319; -.
DR   PaxDb; Q0P561; -.
DR   Ensembl; ENSBTAT00000017319; ENSBTAP00000017319; ENSBTAG00000013026.
DR   GeneID; 768326; -.
DR   KEGG; bta:768326; -.
DR   CTD; 132203; -.
DR   VEuPathDB; HostDB:ENSBTAG00000013026; -.
DR   VGNC; VGNC:35086; SNTN.
DR   eggNOG; ENOG502S6AH; Eukaryota.
DR   GeneTree; ENSGT00390000003322; -.
DR   InParanoid; Q0P561; -.
DR   OMA; CTHSTQD; -.
DR   OrthoDB; 1529608at2759; -.
DR   Proteomes; UP000009136; Chromosome 22.
DR   Bgee; ENSBTAG00000013026; Expressed in olfactory segment of nasal mucosa and 52 other tissues.
DR   GO; GO:0005929; C:cilium; IEA:UniProtKB-SubCell.
DR   GO; GO:0005509; F:calcium ion binding; IBA:GO_Central.
DR   GO; GO:0048306; F:calcium-dependent protein binding; IBA:GO_Central.
DR   GO; GO:0046914; F:transition metal ion binding; IEA:InterPro.
DR   CDD; cd00213; S-100; 1.
DR   InterPro; IPR011992; EF-hand-dom_pair.
DR   InterPro; IPR000261; EH_dom.
DR   InterPro; IPR034325; S-100_dom.
DR   InterPro; IPR013787; S100_Ca-bd_sub.
DR   InterPro; IPR026790; Sentan.
DR   PANTHER; PTHR11639:SF134; PTHR11639:SF134; 1.
DR   SMART; SM01394; S_100; 1.
DR   SUPFAM; SSF47473; SSF47473; 1.
PE   2: Evidence at transcript level;
KW   Cell projection; Cilium; Reference proteome.
FT   CHAIN           1..147
FT                   /note="Sentan"
FT                   /id="PRO_0000342515"
FT   REGION          14..34
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   147 AA;  16247 MW;  CB9C423F3D1F94C6 CRC64;
     MCGCVHSTQD QALRLEGEPN PPAAPTSTLA PKNMPKSISI SKQLASIKAL RKGSDLEKAI
     ATAALVFRNS SDPDGKLRKA TAKNLLQTQF KNFAEGQETK ARYKDLLSEL DEHTENKLDF
     EDFMVLLLSV TIMSDLLQNI WSVKITQ