SNTAN_CHICK
ID SNTAN_CHICK Reviewed; 144 AA.
AC B7FF67;
DT 26-MAY-2009, integrated into UniProtKB/Swiss-Prot.
DT 10-FEB-2009, sequence version 1.
DT 03-AUG-2022, entry version 70.
DE RecName: Full=Sentan {ECO:0000312|EMBL:FAA00431.1};
DE AltName: Full=Protein S100-A1-like;
DE AltName: Full=S100 calcium-binding protein A1-like {ECO:0000250|UniProtKB:Q8C9X1};
GN Name=SNTN {ECO:0000250|UniProtKB:Q8C9X1};
GN Synonyms=S100A1L {ECO:0000250|UniProtKB:Q8C9X1};
OS Gallus gallus (Chicken).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae;
OC Phasianinae; Gallus.
OX NCBI_TaxID=9031;
RN [1] {ECO:0000305}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RX PubMed=15590942; DOI=10.1101/gr.3011405;
RA Hubbard S.J., Grafham D.V., Beattie K.J., Overton I.M., McLaren S.R.,
RA Croning M.D.R., Boardman P.E., Bonfield J.K., Burnside J., Davies R.M.,
RA Farrell E.R., Francis M.D., Griffiths-Jones S., Humphray S.J., Hyland C.,
RA Scott C.E., Tang H., Taylor R.G., Tickle C., Brown W.R.A., Birney E.,
RA Rogers J., Wilson S.A.;
RT "Transcriptome analysis for the chicken based on 19,626 finished cDNA
RT sequences and 485,337 expressed sequence tags.";
RL Genome Res. 15:174-183(2005).
RN [2] {ECO:0000305, ECO:0000312|EMBL:FAA00431.1}
RP IDENTIFICATION.
RX PubMed=18829862; DOI=10.1091/mbc.e08-07-0691;
RA Kubo A., Yuba-Kubo A., Tsukita S., Tsukita S., Amagai M.;
RT "Sentan: a novel specific component of the apical structure of vertebrate
RT motile cilia.";
RL Mol. Biol. Cell 19:5338-5346(2008).
CC -!- FUNCTION: May be a component of the linker structure that bridges the
CC ciliary membrane and peripheral singlet microtubules.
CC {ECO:0000250|UniProtKB:Q8C9X1}.
CC -!- SUBCELLULAR LOCATION: Cell projection, cilium
CC {ECO:0000250|UniProtKB:Q8C9X1}. Note=Expressed exclusively at the
CC cilium tip where it localizes between the cell membrane and peripheral
CC A-subfibers. {ECO:0000250|UniProtKB:Q8C9X1}.
CC -!- MISCELLANEOUS: 'Sentan' means 'tip' in Japanese.
CC {ECO:0000269|PubMed:18829862}.
CC -!- SIMILARITY: Belongs to the S-100 family. {ECO:0000255}.
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DR EMBL; BX933188; -; NOT_ANNOTATED_CDS; mRNA.
DR EMBL; BR000725; FAA00431.1; -; mRNA.
DR RefSeq; NP_001136319.1; NM_001142847.1.
DR AlphaFoldDB; B7FF67; -.
DR SMR; B7FF67; -.
DR STRING; 9031.ENSGALP00000011789; -.
DR PaxDb; B7FF67; -.
DR Ensembl; ENSGALT00000011803; ENSGALP00000011789; ENSGALG00000007288.
DR GeneID; 416076; -.
DR KEGG; gga:416076; -.
DR CTD; 132203; -.
DR VEuPathDB; HostDB:geneid_416076; -.
DR eggNOG; ENOG502S6AH; Eukaryota.
DR GeneTree; ENSGT00390000003322; -.
DR HOGENOM; CLU_148109_0_0_1; -.
DR InParanoid; B7FF67; -.
DR OMA; CTHSTQD; -.
DR OrthoDB; 1529608at2759; -.
DR PhylomeDB; B7FF67; -.
DR TreeFam; TF335855; -.
DR PRO; PR:B7FF67; -.
DR Proteomes; UP000000539; Chromosome 12.
DR Bgee; ENSGALG00000007288; Expressed in ovary and 1 other tissue.
DR GO; GO:0005929; C:cilium; IEA:UniProtKB-SubCell.
DR GO; GO:0005509; F:calcium ion binding; IBA:GO_Central.
DR GO; GO:0048306; F:calcium-dependent protein binding; IBA:GO_Central.
DR GO; GO:0046914; F:transition metal ion binding; IEA:InterPro.
DR CDD; cd00213; S-100; 1.
DR InterPro; IPR011992; EF-hand-dom_pair.
DR InterPro; IPR034325; S-100_dom.
DR InterPro; IPR013787; S100_Ca-bd_sub.
DR InterPro; IPR026790; Sentan.
DR PANTHER; PTHR11639:SF134; PTHR11639:SF134; 1.
DR SMART; SM01394; S_100; 1.
DR SUPFAM; SSF47473; SSF47473; 1.
PE 2: Evidence at transcript level;
KW Cell projection; Cilium; Reference proteome.
FT CHAIN 1..144
FT /note="Sentan"
FT /id="PRO_0000376053"
FT REGION 1..31
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 144 AA; 15758 MW; A3BAC2A25357C8A9 CRC64;
MCGCRASVPS TKHYSVNPAP TTRSPPAAAG MPKRIPIAKQ LASIKALEKG SDLEKAFATA
ALVYNNSADP EGKLSKAETK SLLQTQFSRF IQGQENKPKY QEMISALDEE PEKKIDFEDF
MISLVSLALL SDLLQEIKNV KSTK