SNU13_ASHGO
ID SNU13_ASHGO Reviewed; 127 AA.
AC Q757T2;
DT 12-JUN-2007, integrated into UniProtKB/Swiss-Prot.
DT 05-JUL-2004, sequence version 1.
DT 25-MAY-2022, entry version 91.
DE RecName: Full=13 kDa ribonucleoprotein-associated protein;
GN Name=SNU13; OrderedLocusNames=AEL070W;
OS Ashbya gossypii (strain ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056)
OS (Yeast) (Eremothecium gossypii).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC Saccharomycetales; Saccharomycetaceae; Eremothecium.
OX NCBI_TaxID=284811;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056;
RX PubMed=15001715; DOI=10.1126/science.1095781;
RA Dietrich F.S., Voegeli S., Brachat S., Lerch A., Gates K., Steiner S.,
RA Mohr C., Poehlmann R., Luedi P., Choi S., Wing R.A., Flavier A.,
RA Gaffney T.D., Philippsen P.;
RT "The Ashbya gossypii genome as a tool for mapping the ancient Saccharomyces
RT cerevisiae genome.";
RL Science 304:304-307(2004).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056;
RX PubMed=23749448; DOI=10.1534/g3.112.002881;
RA Dietrich F.S., Voegeli S., Kuo S., Philippsen P.;
RT "Genomes of Ashbya fungi isolated from insects reveal four mating-type
RT loci, numerous translocations, lack of transposons, and distinct gene
RT duplications.";
RL G3 (Bethesda) 3:1225-1239(2013).
CC -!- FUNCTION: Common component of the spliceosome and rRNA processing
CC machinery. In association with the spliceosomal U4/U6.U5 tri-snRNP
CC particle, required for splicing of pre-mRNA. In association with box
CC C/D snoRNPs, required for processing of pre-ribosomal RNA (rRNA) and
CC site-specific 2'-O-methylation of substrate RNAs. Essential for the
CC accumulation and stability of U4 snRNA, U6 snRNA, and box C/D snoRNAs
CC (By similarity). {ECO:0000250}.
CC -!- SUBUNIT: Component of the U3 snoRNP particle. Binds to the C'/D and B/C
CC motifs in U3 snoRNA. Component of the 25S U4/U6.U5 tri-snRNP particle,
CC a subcomplex of the spliceosome. Binds to the 5' stem-loop of U4 snRNA
CC (By similarity). {ECO:0000250}.
CC -!- SUBCELLULAR LOCATION: Nucleus, nucleolus {ECO:0000250}.
CC -!- SIMILARITY: Belongs to the eukaryotic ribosomal protein eL8 family.
CC {ECO:0000305}.
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DR EMBL; AE016818; AAS52615.1; -; Genomic_DNA.
DR RefSeq; NP_984791.1; NM_210145.1.
DR AlphaFoldDB; Q757T2; -.
DR SMR; Q757T2; -.
DR STRING; 33169.AAS52615; -.
DR EnsemblFungi; AAS52615; AAS52615; AGOS_AEL070W.
DR GeneID; 4620983; -.
DR KEGG; ago:AGOS_AEL070W; -.
DR eggNOG; KOG3387; Eukaryota.
DR HOGENOM; CLU_084513_4_1_1; -.
DR InParanoid; Q757T2; -.
DR OMA; KPFYVRF; -.
DR Proteomes; UP000000591; Chromosome V.
DR GO; GO:0031428; C:box C/D RNP complex; IBA:GO_Central.
DR GO; GO:0005730; C:nucleolus; IEA:UniProtKB-SubCell.
DR GO; GO:0071011; C:precatalytic spliceosome; IBA:GO_Central.
DR GO; GO:0032040; C:small-subunit processome; IBA:GO_Central.
DR GO; GO:0046540; C:U4/U6 x U5 tri-snRNP complex; IBA:GO_Central.
DR GO; GO:0003723; F:RNA binding; IBA:GO_Central.
DR GO; GO:0034511; F:U3 snoRNA binding; IEA:EnsemblFungi.
DR GO; GO:0030621; F:U4 snRNA binding; IEA:EnsemblFungi.
DR GO; GO:0000494; P:box C/D RNA 3'-end processing; IEA:EnsemblFungi.
DR GO; GO:0000470; P:maturation of LSU-rRNA; IBA:GO_Central.
DR GO; GO:0030490; P:maturation of SSU-rRNA; IBA:GO_Central.
DR GO; GO:0000462; P:maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA); IEA:EnsemblFungi.
DR GO; GO:0000398; P:mRNA splicing, via spliceosome; IBA:GO_Central.
DR GO; GO:1905216; P:positive regulation of RNA binding; IEA:EnsemblFungi.
DR GO; GO:0000452; P:snoRNA guided rRNA 2'-O-methylation; IEA:EnsemblFungi.
DR Gene3D; 3.30.1330.30; -; 1.
DR InterPro; IPR002415; H/ACA_rnp_Nhp2-like.
DR InterPro; IPR029064; L30e-like.
DR InterPro; IPR004038; Ribosomal_L7Ae/L30e/S12e/Gad45.
DR InterPro; IPR018492; Ribosomal_L7Ae/L8/Nhp2.
DR InterPro; IPR004037; Ribosomal_L7Ae_CS.
DR Pfam; PF01248; Ribosomal_L7Ae; 1.
DR PRINTS; PR00881; L7ARS6FAMILY.
DR PRINTS; PR00883; NUCLEARHMG.
DR SUPFAM; SSF55315; SSF55315; 1.
DR PROSITE; PS01082; RIBOSOMAL_L7AE; 1.
PE 3: Inferred from homology;
KW mRNA processing; mRNA splicing; Nucleus; Reference proteome;
KW Ribonucleoprotein; Ribosome biogenesis; RNA-binding; rRNA processing;
KW Spliceosome.
FT CHAIN 1..127
FT /note="13 kDa ribonucleoprotein-associated protein"
FT /id="PRO_0000290656"
SQ SEQUENCE 127 AA; 13706 MW; B2B5A04E0656C87E CRC64;
MSSTPNPKAF PLADAALTQQ ILDVVQQASN MRQLKKGANE ATKTLNRGIS EFIIMAADCE
PIEILLHLPL LCEDKNVPYV FVPSRVALGR ACGVSRPVIA ASITTNDASA IKSQIYAVKD
KIETLLI
