ID   SNU13_CRYNJ             Reviewed;         127 AA.
AC   P0CQ52; Q55P84; Q5KE73;
DT   28-JUN-2011, integrated into UniProtKB/Swiss-Prot.
DT   28-JUN-2011, sequence version 1.
DT   25-MAY-2022, entry version 42.
DE   RecName: Full=13 kDa ribonucleoprotein-associated protein;
GN   Name=SNU13; OrderedLocusNames=CNG01500;
OS   Cryptococcus neoformans var. neoformans serotype D (strain JEC21 / ATCC
OS   MYA-565) (Filobasidiella neoformans).
OC   Eukaryota; Fungi; Dikarya; Basidiomycota; Agaricomycotina; Tremellomycetes;
OC   Tremellales; Cryptococcaceae; Cryptococcus;
OC   Cryptococcus neoformans species complex.
OX   NCBI_TaxID=214684;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=JEC21 / ATCC MYA-565;
RX   PubMed=15653466; DOI=10.1126/science.1103773;
RA   Loftus B.J., Fung E., Roncaglia P., Rowley D., Amedeo P., Bruno D.,
RA   Vamathevan J., Miranda M., Anderson I.J., Fraser J.A., Allen J.E.,
RA   Bosdet I.E., Brent M.R., Chiu R., Doering T.L., Donlin M.J., D'Souza C.A.,
RA   Fox D.S., Grinberg V., Fu J., Fukushima M., Haas B.J., Huang J.C.,
RA   Janbon G., Jones S.J.M., Koo H.L., Krzywinski M.I., Kwon-Chung K.J.,
RA   Lengeler K.B., Maiti R., Marra M.A., Marra R.E., Mathewson C.A.,
RA   Mitchell T.G., Pertea M., Riggs F.R., Salzberg S.L., Schein J.E.,
RA   Shvartsbeyn A., Shin H., Shumway M., Specht C.A., Suh B.B., Tenney A.,
RA   Utterback T.R., Wickes B.L., Wortman J.R., Wye N.H., Kronstad J.W.,
RA   Lodge J.K., Heitman J., Davis R.W., Fraser C.M., Hyman R.W.;
RT   "The genome of the basidiomycetous yeast and human pathogen Cryptococcus
RT   neoformans.";
RL   Science 307:1321-1324(2005).
CC   -!- FUNCTION: Common component of the spliceosome and rRNA processing
CC       machinery. In association with the spliceosomal U4/U6.U5 tri-snRNP
CC       particle, required for splicing of pre-mRNA. In association with box
CC       C/D snoRNPs, required for processing of pre-ribosomal RNA (rRNA) and
CC       site-specific 2'-O-methylation of substrate RNAs. Essential for the
CC       accumulation and stability of U4 snRNA, U6 snRNA, and box C/D snoRNAs
CC       (By similarity). {ECO:0000250}.
CC   -!- SUBUNIT: Component of the U3 snoRNP particle. Binds to the C'/D and B/C
CC       motifs in U3 snoRNA. Component of the 25S U4/U6.U5 tri-snRNP particle,
CC       a subcomplex of the spliceosome. Binds to the 5' stem-loop of U4 snRNA
CC       (By similarity). {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Nucleus, nucleolus {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the eukaryotic ribosomal protein eL8 family.
CC       {ECO:0000305}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; AE017347; AAW44542.1; -; Genomic_DNA.
DR   RefSeq; XP_571849.1; XM_571849.1.
DR   AlphaFoldDB; P0CQ52; -.
DR   SMR; P0CQ52; -.
DR   STRING; 5207.AAW44542; -.
DR   PaxDb; P0CQ52; -.
DR   EnsemblFungi; AAW44542; AAW44542; CNG01500.
DR   GeneID; 3258685; -.
DR   KEGG; cne:CNG01500; -.
DR   VEuPathDB; FungiDB:CNG01500; -.
DR   eggNOG; KOG3387; Eukaryota.
DR   HOGENOM; CLU_084513_4_1_1; -.
DR   InParanoid; P0CQ52; -.
DR   OMA; KPFYVRF; -.
DR   OrthoDB; 1497609at2759; -.
DR   Proteomes; UP000002149; Chromosome 7.
DR   GO; GO:0031428; C:box C/D RNP complex; IBA:GO_Central.
DR   GO; GO:0005730; C:nucleolus; IEA:UniProtKB-SubCell.
DR   GO; GO:0071011; C:precatalytic spliceosome; IBA:GO_Central.
DR   GO; GO:0032040; C:small-subunit processome; IBA:GO_Central.
DR   GO; GO:0046540; C:U4/U6 x U5 tri-snRNP complex; IBA:GO_Central.
DR   GO; GO:0003723; F:RNA binding; IBA:GO_Central.
DR   GO; GO:0000470; P:maturation of LSU-rRNA; IBA:GO_Central.
DR   GO; GO:0030490; P:maturation of SSU-rRNA; IBA:GO_Central.
DR   GO; GO:0000398; P:mRNA splicing, via spliceosome; IBA:GO_Central.
DR   Gene3D; 3.30.1330.30; -; 1.
DR   InterPro; IPR002415; H/ACA_rnp_Nhp2-like.
DR   InterPro; IPR029064; L30e-like.
DR   InterPro; IPR004038; Ribosomal_L7Ae/L30e/S12e/Gad45.
DR   InterPro; IPR018492; Ribosomal_L7Ae/L8/Nhp2.
DR   InterPro; IPR004037; Ribosomal_L7Ae_CS.
DR   Pfam; PF01248; Ribosomal_L7Ae; 1.
DR   PRINTS; PR00881; L7ARS6FAMILY.
DR   PRINTS; PR00883; NUCLEARHMG.
DR   SUPFAM; SSF55315; SSF55315; 1.
DR   PROSITE; PS01082; RIBOSOMAL_L7AE; 1.
PE   3: Inferred from homology;
KW   mRNA processing; mRNA splicing; Nucleus; Reference proteome;
KW   Ribonucleoprotein; Ribosome biogenesis; RNA-binding; rRNA processing;
KW   Spliceosome.
FT   CHAIN           1..127
FT                   /note="13 kDa ribonucleoprotein-associated protein"
FT                   /id="PRO_0000290659"
SQ   SEQUENCE   127 AA;  13946 MW;  CE0245D9EFC59E27 CRC64;
     MSAQPNPKAF PLANAQLTNQ ILDLIQQAQH YKQLKKGANE ATKTLNRGIC EFIVMTADVE
     PIEIVLHLPL LCEDKNVPYV FLPSKTALGR ACGVSRPVIA ASVTTNEARE LNAQIQAVKN
     EIEKLLI