ID   SNU71_CANAL             Reviewed;         614 AA.
AC   Q5AM84; A0A1D8PGG0; Q5ALT3;
DT   20-MAY-2008, integrated into UniProtKB/Swiss-Prot.
DT   10-MAY-2017, sequence version 2.
DT   03-AUG-2022, entry version 69.
DE   RecName: Full=U1 small nuclear ribonucleoprotein component SNU71;
GN   Name=SNU71; OrderedLocusNames=CAALFM_C201820CA;
GN   ORFNames=CaO19.1491, CaO19.9068;
OS   Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC   Saccharomycetales; Debaryomycetaceae; Candida/Lodderomyces clade; Candida.
OX   NCBI_TaxID=237561;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=SC5314 / ATCC MYA-2876;
RX   PubMed=15123810; DOI=10.1073/pnas.0401648101;
RA   Jones T., Federspiel N.A., Chibana H., Dungan J., Kalman S., Magee B.B.,
RA   Newport G., Thorstenson Y.R., Agabian N., Magee P.T., Davis R.W.,
RA   Scherer S.;
RT   "The diploid genome sequence of Candida albicans.";
RL   Proc. Natl. Acad. Sci. U.S.A. 101:7329-7334(2004).
RN   [2]
RP   GENOME REANNOTATION.
RC   STRAIN=SC5314 / ATCC MYA-2876;
RX   PubMed=17419877; DOI=10.1186/gb-2007-8-4-r52;
RA   van het Hoog M., Rast T.J., Martchenko M., Grindle S., Dignard D.,
RA   Hogues H., Cuomo C., Berriman M., Scherer S., Magee B.B., Whiteway M.,
RA   Chibana H., Nantel A., Magee P.T.;
RT   "Assembly of the Candida albicans genome into sixteen supercontigs aligned
RT   on the eight chromosomes.";
RL   Genome Biol. 8:RESEARCH52.1-RESEARCH52.12(2007).
RN   [3]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA], AND GENOME REANNOTATION.
RC   STRAIN=SC5314 / ATCC MYA-2876;
RX   PubMed=24025428; DOI=10.1186/gb-2013-14-9-r97;
RA   Muzzey D., Schwartz K., Weissman J.S., Sherlock G.;
RT   "Assembly of a phased diploid Candida albicans genome facilitates allele-
RT   specific measurements and provides a simple model for repeat and indel
RT   structure.";
RL   Genome Biol. 14:RESEARCH97.1-RESEARCH97.14(2013).
CC   -!- FUNCTION: Component of the U1 snRNP particle, which recognizes and
CC       binds the 5'-splice site of pre-mRNA. Together with other non-snRNP
CC       factors, U1 snRNP forms the spliceosomal commitment complex, that
CC       targets pre-mRNA to the splicing pathway (By similarity).
CC       {ECO:0000250}.
CC   -!- SUBUNIT: Component of the U1 snRNP particle, a subcomplex of the
CC       spliceosome. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250}. Nucleus {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the SNU71 family. {ECO:0000305}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; CP017624; AOW27225.1; -; Genomic_DNA.
DR   RefSeq; XP_722539.2; XM_717446.2.
DR   AlphaFoldDB; Q5AM84; -.
DR   SMR; Q5AM84; -.
DR   BioGRID; 1218925; 1.
DR   STRING; 237561.Q5AM84; -.
DR   PRIDE; Q5AM84; -.
DR   GeneID; 3635831; -.
DR   KEGG; cal:CAALFM_C201820CA; -.
DR   CGD; CAL0000187181; orf19.9068.
DR   VEuPathDB; FungiDB:C2_01820C_A; -.
DR   eggNOG; KOG2253; Eukaryota.
DR   HOGENOM; CLU_478950_0_0_1; -.
DR   InParanoid; Q5AM84; -.
DR   OrthoDB; 1314856at2759; -.
DR   PRO; PR:Q5AM84; -.
DR   Proteomes; UP000000559; Chromosome 2.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0005681; C:spliceosomal complex; IEA:UniProtKB-KW.
DR   GO; GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.
DR   GO; GO:0008380; P:RNA splicing; IEA:UniProtKB-KW.
DR   InterPro; IPR002483; PWI_dom.
DR   Pfam; PF01480; PWI; 1.
PE   3: Inferred from homology;
KW   Coiled coil; Cytoplasm; mRNA processing; mRNA splicing; Nucleus;
KW   Reference proteome; Ribonucleoprotein; RNA-binding; Spliceosome.
FT   CHAIN           1..614
FT                   /note="U1 small nuclear ribonucleoprotein component SNU71"
FT                   /id="PRO_0000333455"
FT   REGION          69..98
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          473..526
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COILED          301..327
FT                   /evidence="ECO:0000255"
FT   COILED          450..479
FT                   /evidence="ECO:0000255"
FT   COMPBIAS        75..89
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        477..523
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   614 AA;  70502 MW;  91E2D6F7CC5055A2 CRC64;
     MTAGDNSIEY VNPYSLSQTI NSDLISILDP NGSTTSIIKP QLNYQIPIFK SIDVSNLIDL
     NNTKIQTQTN ETRINKAKDS SDDHQNNPSS KDYDTSGENI VGGIDDIVED IKLYVSIDKL
     KPENFQNQLT TIIINQFPTN LKSNLIEQLL KMLMNLKKFV WSFINHELID LKLIFIKFDQ
     LKDLKWFLLT YCDHISQLIP NVTIITNDKV NEYLNNNKDS SLAKVEPSKI TDNLKAKINL
     IINNPINYTK GKKNSGTEDL DQVLDSYSNY KVDNNDLIDI PNNMKENIIK DIIRFRSRML
     LIEKEQRKKE IEMERIKTKN KLKELFEGIK ENSTDSTTRK ATNKAAVGVT ISPKVSHRDE
     YEDMNDKEYE EFIAVEERNK LNDQYNKKLK SFQNNQHAEY MKLTNKLKSL QNYESDLIDN
     KLKYIDNLKN YQTNGLAHLY THNYSDYLRM RSQKRSLEET KDAEDVKQEL EEIKKNGGQV
     ASTNTNTNTK PSTYSSGVSE LATTSVETPK STTTTTTTND TTDEPVAKKS KLAKEIIIID
     LPPTVKQSLQ EKIVELVENS LGIKDEFLIQ VINENLEASN LDNKQELIDE LVQVLDEDAE
     SLVNELWDYI ETMV