ID   SNU71_LODEL             Reviewed;         627 AA.
AC   A5DUA3;
DT   20-MAY-2008, integrated into UniProtKB/Swiss-Prot.
DT   12-JUN-2007, sequence version 1.
DT   03-AUG-2022, entry version 53.
DE   RecName: Full=U1 small nuclear ribonucleoprotein component SNU71;
GN   Name=SNU71; ORFNames=LELG_00939;
OS   Lodderomyces elongisporus (strain ATCC 11503 / CBS 2605 / JCM 1781 / NBRC
OS   1676 / NRRL YB-4239) (Yeast) (Saccharomyces elongisporus).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC   Saccharomycetales; Debaryomycetaceae; Candida/Lodderomyces clade;
OC   Lodderomyces.
OX   NCBI_TaxID=379508;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 11503 / BCRC 21390 / CBS 2605 / JCM 1781 / NBRC 1676 / NRRL
RC   YB-4239;
RX   PubMed=19465905; DOI=10.1038/nature08064;
RA   Butler G., Rasmussen M.D., Lin M.F., Santos M.A.S., Sakthikumar S.,
RA   Munro C.A., Rheinbay E., Grabherr M., Forche A., Reedy J.L., Agrafioti I.,
RA   Arnaud M.B., Bates S., Brown A.J.P., Brunke S., Costanzo M.C.,
RA   Fitzpatrick D.A., de Groot P.W.J., Harris D., Hoyer L.L., Hube B.,
RA   Klis F.M., Kodira C., Lennard N., Logue M.E., Martin R., Neiman A.M.,
RA   Nikolaou E., Quail M.A., Quinn J., Santos M.C., Schmitzberger F.F.,
RA   Sherlock G., Shah P., Silverstein K.A.T., Skrzypek M.S., Soll D.,
RA   Staggs R., Stansfield I., Stumpf M.P.H., Sudbery P.E., Srikantha T.,
RA   Zeng Q., Berman J., Berriman M., Heitman J., Gow N.A.R., Lorenz M.C.,
RA   Birren B.W., Kellis M., Cuomo C.A.;
RT   "Evolution of pathogenicity and sexual reproduction in eight Candida
RT   genomes.";
RL   Nature 459:657-662(2009).
CC   -!- FUNCTION: Component of the U1 snRNP particle, which recognizes and
CC       binds the 5'-splice site of pre-mRNA. Together with other non-snRNP
CC       factors, U1 snRNP forms the spliceosomal commitment complex, that
CC       targets pre-mRNA to the splicing pathway (By similarity).
CC       {ECO:0000250}.
CC   -!- SUBUNIT: Component of the U1 snRNP particle, a subcomplex of the
CC       spliceosome. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250}. Nucleus {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the SNU71 family. {ECO:0000305}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; CH981524; EDK42761.1; -; Genomic_DNA.
DR   RefSeq; XP_001528419.1; XM_001528369.1.
DR   AlphaFoldDB; A5DUA3; -.
DR   SMR; A5DUA3; -.
DR   PRIDE; A5DUA3; -.
DR   EnsemblFungi; EDK42761; EDK42761; LELG_00939.
DR   GeneID; 5235870; -.
DR   KEGG; lel:LELG_00939; -.
DR   VEuPathDB; FungiDB:LELG_00939; -.
DR   eggNOG; ENOG502S6GF; Eukaryota.
DR   HOGENOM; CLU_478950_0_0_1; -.
DR   InParanoid; A5DUA3; -.
DR   OMA; NTITRHY; -.
DR   OrthoDB; 1314856at2759; -.
DR   Proteomes; UP000001996; Unassembled WGS sequence.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0005681; C:spliceosomal complex; IEA:UniProtKB-KW.
DR   GO; GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.
DR   GO; GO:0008380; P:RNA splicing; IEA:UniProtKB-KW.
DR   InterPro; IPR002483; PWI_dom.
DR   Pfam; PF01480; PWI; 1.
PE   3: Inferred from homology;
KW   Coiled coil; Cytoplasm; mRNA processing; mRNA splicing; Nucleus;
KW   Reference proteome; Ribonucleoprotein; RNA-binding; Spliceosome.
FT   CHAIN           1..627
FT                   /note="U1 small nuclear ribonucleoprotein component SNU71"
FT                   /id="PRO_0000333459"
FT   REGION          337..368
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COILED          300..442
FT                   /evidence="ECO:0000255"
FT   COILED          469..513
FT                   /evidence="ECO:0000255"
FT   COMPBIAS        340..365
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   627 AA;  72836 MW;  1AFF2BA654284644 CRC64;
     MYRTSTLASK TTSTSGIAFV SPYSIPASNH TKLLSLLSHL ESPSNERSES LHLNVNVPVP
     VQFDASEIID LNNTKILTQS AELQSHGKNK LPSNQLKDTV NVNDEPELYL DIKTIQPTNL
     QEQLCIVVLN NFPNLKNIAV EKVLLHLIEL GLEDRIEGQQ DGKEIKDKAR KFAWSLVNYE
     FIDLKTIFIR FNHVKDVKWF VKTFHDIDAI LPKVELIYSA QIDEYLKDLE VLPSVSVTDR
     LKNQIKLILY NSKNLAKPKI KGFEDLDRAM QSYSDYMVDN NDLIDVPNNM KDSIIREIIR
     FRTKMLSIEK ENRQKQIEIE REKTKQKLNK LFEGIKEASD AQQEQQREQE QEQEQEQEQG
     QKQKEKFATA RTNNQAAETF VMPEEHEELD DKEYDAYVKA QRIAKQNKDY NQRLNAFKAK
     EEAERTRLEL EIKRLQDYEV NVWDNKAATI AKFRNYESNG LANLYEMNYN EYLKQRVAKR
     TLEEELDRAD IEKETQELEN EVQPIKHTLD TYESKHAEPE AKRAKFNADQ NEADIEVPMS
     PLEKDKRVII VKELSLAKQN QIKTKIDDLV EDCLGVKDEL LLDVIFQSLE SSNFDGRDAL
     VTELEEFLDE DAVKLVDLLY DFVRSLA