SNU71_PICST
ID SNU71_PICST Reviewed; 579 AA.
AC A3LRM6;
DT 20-MAY-2008, integrated into UniProtKB/Swiss-Prot.
DT 24-JUL-2007, sequence version 2.
DT 25-MAY-2022, entry version 58.
DE RecName: Full=U1 small nuclear ribonucleoprotein component SNU71;
GN Name=SNU71; ORFNames=PICST_56888;
OS Scheffersomyces stipitis (strain ATCC 58785 / CBS 6054 / NBRC 10063 / NRRL
OS Y-11545) (Yeast) (Pichia stipitis).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC Saccharomycetales; Debaryomycetaceae; Scheffersomyces.
OX NCBI_TaxID=322104;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 58785 / CBS 6054 / NBRC 10063 / NRRL Y-11545;
RX PubMed=17334359; DOI=10.1038/nbt1290;
RA Jeffries T.W., Grigoriev I.V., Grimwood J., Laplaza J.M., Aerts A.,
RA Salamov A., Schmutz J., Lindquist E., Dehal P., Shapiro H., Jin Y.-S.,
RA Passoth V., Richardson P.M.;
RT "Genome sequence of the lignocellulose-bioconverting and xylose-fermenting
RT yeast Pichia stipitis.";
RL Nat. Biotechnol. 25:319-326(2007).
CC -!- FUNCTION: Component of the U1 snRNP particle, which recognizes and
CC binds the 5'-splice site of pre-mRNA. Together with other non-snRNP
CC factors, U1 snRNP forms the spliceosomal commitment complex, that
CC targets pre-mRNA to the splicing pathway (By similarity).
CC {ECO:0000250}.
CC -!- SUBUNIT: Component of the U1 snRNP particle, a subcomplex of the
CC spliceosome. {ECO:0000250}.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250}. Nucleus {ECO:0000250}.
CC -!- SIMILARITY: Belongs to the SNU71 family. {ECO:0000305}.
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DR EMBL; CP000497; ABN65411.2; -; Genomic_DNA.
DR RefSeq; XP_001383440.2; XM_001383403.1.
DR AlphaFoldDB; A3LRM6; -.
DR SMR; A3LRM6; -.
DR EnsemblFungi; ABN65411; ABN65411; PICST_56888.
DR GeneID; 4838042; -.
DR KEGG; pic:PICST_56888; -.
DR eggNOG; ENOG502S6GF; Eukaryota.
DR HOGENOM; CLU_478950_0_0_1; -.
DR InParanoid; A3LRM6; -.
DR OMA; NTITRHY; -.
DR OrthoDB; 1314856at2759; -.
DR Proteomes; UP000002258; Chromosome 3.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0005681; C:spliceosomal complex; IEA:UniProtKB-KW.
DR GO; GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
DR GO; GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.
DR GO; GO:0008380; P:RNA splicing; IEA:UniProtKB-KW.
DR InterPro; IPR002483; PWI_dom.
DR Pfam; PF01480; PWI; 1.
PE 3: Inferred from homology;
KW Coiled coil; Cytoplasm; mRNA processing; mRNA splicing; Nucleus;
KW Reference proteome; Ribonucleoprotein; RNA-binding; Spliceosome.
FT CHAIN 1..579
FT /note="U1 small nuclear ribonucleoprotein component SNU71"
FT /id="PRO_0000333460"
FT REGION 76..101
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 484..505
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 292..380
FT /evidence="ECO:0000255"
SQ SEQUENCE 579 AA; 66988 MW; E633B93FE1289A6E CRC64;
MVAILPDSIT AETAPYFLPE SNNSKLLEFL KPLPFSTIKS QSIPAVVGTQ VPVFKSIDVS
NLIEKTSNRL IWQTASERRR DDARSTSEEL ENPENEIEED PQHFVEIQEL LPKSLKDQLS
LVVVDNFPNV KQYAIEKIVD SLVDTRKYKW SHVHYEFADN RSVYIRFEHV PDAKWFVDTY
SSVLPDILSN KNIKVIHNNH IDEVLDELSD FKADPKSTVN SKVVSKIGSI LKNKRNFERI
SKRSGTEDLD EVLAYYSKYE VDSNDLIDVP TNMREAIVKD IVRFRSKVLL IERDNRKKEI
ELEREKTKDR LKKLFAGLKE TNDDINMDSE TTKDLPSNIV NEYDDLSDDE YEELLKTGEK
KKLDKLYQDK SHQLQSLETR ERLYLTKKLE DLNNYEDDLI NNKIKYIEDF KNIEESTNSN
NNDISSLVSL YFNNHAQYLK VRNHKRSAEE ALDAKDEDDE KKEELSTKSQ DFVSLKKAKN
TLEKDTEDAV PVADNAESET EPSRIEVDQT SKLQSKIVEL VEEYLGIVDE FLVEVINENL
NKHNLSAKDE LMEELSEVLD DDSANLVNDL WNYVSTIAI
