SNUT3_SCHPO
ID SNUT3_SCHPO Reviewed; 244 AA.
AC O74418;
DT 05-MAY-2009, integrated into UniProtKB/Swiss-Prot.
DT 01-NOV-1998, sequence version 1.
DT 25-MAY-2022, entry version 102.
DE RecName: Full=U4/U6.U5 tri-snRNP-associated protein 3-like protein C162.01c;
GN ORFNames=SPCC162.01c;
OS Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina;
OC Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae;
OC Schizosaccharomyces.
OX NCBI_TaxID=284812;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=972 / ATCC 24843;
RX PubMed=11859360; DOI=10.1038/nature724;
RA Wood V., Gwilliam R., Rajandream M.A., Lyne M.H., Lyne R., Stewart A.,
RA Sgouros J.G., Peat N., Hayles J., Baker S.G., Basham D., Bowman S.,
RA Brooks K., Brown D., Brown S., Chillingworth T., Churcher C.M., Collins M.,
RA Connor R., Cronin A., Davis P., Feltwell T., Fraser A., Gentles S.,
RA Goble A., Hamlin N., Harris D.E., Hidalgo J., Hodgson G., Holroyd S.,
RA Hornsby T., Howarth S., Huckle E.J., Hunt S., Jagels K., James K.D.,
RA Jones L., Jones M., Leather S., McDonald S., McLean J., Mooney P.,
RA Moule S., Mungall K.L., Murphy L.D., Niblett D., Odell C., Oliver K.,
RA O'Neil S., Pearson D., Quail M.A., Rabbinowitsch E., Rutherford K.M.,
RA Rutter S., Saunders D., Seeger K., Sharp S., Skelton J., Simmonds M.N.,
RA Squares R., Squares S., Stevens K., Taylor K., Taylor R.G., Tivey A.,
RA Walsh S.V., Warren T., Whitehead S., Woodward J.R., Volckaert G., Aert R.,
RA Robben J., Grymonprez B., Weltjens I., Vanstreels E., Rieger M.,
RA Schaefer M., Mueller-Auer S., Gabel C., Fuchs M., Duesterhoeft A.,
RA Fritzc C., Holzer E., Moestl D., Hilbert H., Borzym K., Langer I., Beck A.,
RA Lehrach H., Reinhardt R., Pohl T.M., Eger P., Zimmermann W., Wedler H.,
RA Wambutt R., Purnelle B., Goffeau A., Cadieu E., Dreano S., Gloux S.,
RA Lelaure V., Mottier S., Galibert F., Aves S.J., Xiang Z., Hunt C.,
RA Moore K., Hurst S.M., Lucas M., Rochet M., Gaillardin C., Tallada V.A.,
RA Garzon A., Thode G., Daga R.R., Cruzado L., Jimenez J., Sanchez M.,
RA del Rey F., Benito J., Dominguez A., Revuelta J.L., Moreno S.,
RA Armstrong J., Forsburg S.L., Cerutti L., Lowe T., McCombie W.R.,
RA Paulsen I., Potashkin J., Shpakovski G.V., Ussery D., Barrell B.G.,
RA Nurse P.;
RT "The genome sequence of Schizosaccharomyces pombe.";
RL Nature 415:871-880(2002).
RN [2]
RP SUBCELLULAR LOCATION [LARGE SCALE ANALYSIS].
RX PubMed=16823372; DOI=10.1038/nbt1222;
RA Matsuyama A., Arai R., Yashiroda Y., Shirai A., Kamata A., Sekido S.,
RA Kobayashi Y., Hashimoto A., Hamamoto M., Hiraoka Y., Horinouchi S.,
RA Yoshida M.;
RT "ORFeome cloning and global analysis of protein localization in the fission
RT yeast Schizosaccharomyces pombe.";
RL Nat. Biotechnol. 24:841-847(2006).
RN [3]
RP PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-121 AND SER-140, AND
RP IDENTIFICATION BY MASS SPECTROMETRY.
RX PubMed=18257517; DOI=10.1021/pr7006335;
RA Wilson-Grady J.T., Villen J., Gygi S.P.;
RT "Phosphoproteome analysis of fission yeast.";
RL J. Proteome Res. 7:1088-1097(2008).
CC -!- FUNCTION: May play a role in mRNA splicing. {ECO:0000250}.
CC -!- SUBUNIT: Part of a tri-snRNP complex. {ECO:0000250}.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000269|PubMed:16823372}.
CC -!- SIMILARITY: Belongs to the SNUT3 family. {ECO:0000305}.
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DR EMBL; CU329672; CAA19581.1; -; Genomic_DNA.
DR PIR; T41030; T41030.
DR RefSeq; NP_588243.1; NM_001023233.2.
DR AlphaFoldDB; O74418; -.
DR BioGRID; 275927; 4.
DR STRING; 4896.SPCC162.01c.1; -.
DR iPTMnet; O74418; -.
DR MaxQB; O74418; -.
DR PaxDb; O74418; -.
DR PRIDE; O74418; -.
DR EnsemblFungi; SPCC162.01c.1; SPCC162.01c.1:pep; SPCC162.01c.
DR GeneID; 2539361; -.
DR KEGG; spo:SPCC162.01c; -.
DR PomBase; SPCC162.01c; -.
DR VEuPathDB; FungiDB:SPCC162.01c; -.
DR eggNOG; KOG3263; Eukaryota.
DR HOGENOM; CLU_1082427_0_0_1; -.
DR InParanoid; O74418; -.
DR OMA; SMKRKYR; -.
DR PRO; PR:O74418; -.
DR Proteomes; UP000002485; Chromosome III.
DR GO; GO:0005634; C:nucleus; HDA:PomBase.
DR GO; GO:0046540; C:U4/U6 x U5 tri-snRNP complex; ISS:PomBase.
DR GO; GO:0003723; F:RNA binding; NAS:PomBase.
DR GO; GO:0045292; P:mRNA cis splicing, via spliceosome; IC:PomBase.
DR InterPro; IPR013957; SNRNP27.
DR Pfam; PF08648; SNRNP27; 1.
PE 1: Evidence at protein level;
KW mRNA processing; mRNA splicing; Nucleus; Phosphoprotein;
KW Reference proteome.
FT CHAIN 1..244
FT /note="U4/U6.U5 tri-snRNP-associated protein 3-like protein
FT C162.01c"
FT /id="PRO_0000374005"
FT REGION 1..192
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 223..244
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 10..184
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT MOD_RES 121
FT /note="Phosphoserine"
FT /evidence="ECO:0000269|PubMed:18257517"
FT MOD_RES 140
FT /note="Phosphoserine"
FT /evidence="ECO:0000269|PubMed:18257517"
SQ SEQUENCE 244 AA; 29381 MW; 74B25C840540B2ED CRC64;
MSSSRSGEHR RNYAQGRNYE SSRSRGDQRD RDYREYRRNY RDERSSRRYE DSQRRDYSPA
RRRDRYERHR ESVREESPRR PVEHERNWQP ELKHGRERFR ERDYEGRRDR KERRDGVSPF
SPEGEGLERK REHEKLQAPS PKEEEERPVD QGDKMDGVKE DKDGSLEVGK SHDAMTRTKS
AEEEIVEQED EATAEMKRIM GFSGFDTTTG KKHGDVGQVY KQKKTKYRQY MNRPGGFNRP
LDNE
