SNWA_DICDI
ID SNWA_DICDI Reviewed; 685 AA.
AC P54705; Q55DS2;
DT 01-OCT-1996, integrated into UniProtKB/Swiss-Prot.
DT 01-OCT-1996, sequence version 1.
DT 25-MAY-2022, entry version 104.
DE RecName: Full=Protein snwA;
GN Name=snwA; ORFNames=DDB_G0269188;
OS Dictyostelium discoideum (Slime mold).
OC Eukaryota; Amoebozoa; Evosea; Eumycetozoa; Dictyostelia; Dictyosteliales;
OC Dictyosteliaceae; Dictyostelium.
OX NCBI_TaxID=44689;
RN [1]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX PubMed=8973337; DOI=10.1016/s0378-1119(96)00483-0;
RA Folk P., Puta F., Krpejsova L., Blahuskova A., Markos A., Rabino M.,
RA Dottin R.P.;
RT "The homolog of chromatin binding protein Bx42 identified in
RT Dictyostelium.";
RL Gene 181:229-231(1996).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=AX4;
RX PubMed=15875012; DOI=10.1038/nature03481;
RA Eichinger L., Pachebat J.A., Gloeckner G., Rajandream M.A., Sucgang R.,
RA Berriman M., Song J., Olsen R., Szafranski K., Xu Q., Tunggal B.,
RA Kummerfeld S., Madera M., Konfortov B.A., Rivero F., Bankier A.T.,
RA Lehmann R., Hamlin N., Davies R., Gaudet P., Fey P., Pilcher K., Chen G.,
RA Saunders D., Sodergren E.J., Davis P., Kerhornou A., Nie X., Hall N.,
RA Anjard C., Hemphill L., Bason N., Farbrother P., Desany B., Just E.,
RA Morio T., Rost R., Churcher C.M., Cooper J., Haydock S., van Driessche N.,
RA Cronin A., Goodhead I., Muzny D.M., Mourier T., Pain A., Lu M., Harper D.,
RA Lindsay R., Hauser H., James K.D., Quiles M., Madan Babu M., Saito T.,
RA Buchrieser C., Wardroper A., Felder M., Thangavelu M., Johnson D.,
RA Knights A., Loulseged H., Mungall K.L., Oliver K., Price C., Quail M.A.,
RA Urushihara H., Hernandez J., Rabbinowitsch E., Steffen D., Sanders M.,
RA Ma J., Kohara Y., Sharp S., Simmonds M.N., Spiegler S., Tivey A.,
RA Sugano S., White B., Walker D., Woodward J.R., Winckler T., Tanaka Y.,
RA Shaulsky G., Schleicher M., Weinstock G.M., Rosenthal A., Cox E.C.,
RA Chisholm R.L., Gibbs R.A., Loomis W.F., Platzer M., Kay R.R.,
RA Williams J.G., Dear P.H., Noegel A.A., Barrell B.G., Kuspa A.;
RT "The genome of the social amoeba Dictyostelium discoideum.";
RL Nature 435:43-57(2005).
RN [3]
RP INTERACTION WITH CYPE.
RC STRAIN=AX3;
RX PubMed=11690648; DOI=10.1016/s0167-4781(01)00301-3;
RA Skruzny M., Ambrozkova M., Fukova I., Martinkova K., Blahuskova A.,
RA Hamplova L., Puta F., Folk P.;
RT "Cyclophilins of a novel subfamily interact with SNW/SKIP coregulator in
RT Dictyostelium discoideum and Schizosaccharomyces pombe.";
RL Biochim. Biophys. Acta 1521:146-151(2001).
CC -!- SUBUNIT: Interacts with cypE. {ECO:0000269|PubMed:11690648}.
CC -!- INTERACTION:
CC P54705; Q9NI62: cypE; NbExp=5; IntAct=EBI-1810591, EBI-1810601;
CC -!- SUBCELLULAR LOCATION: Nucleus.
CC -!- SIMILARITY: Belongs to the SNW family. {ECO:0000305}.
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DR EMBL; U43887; AAB40497.1; -; Genomic_DNA.
DR EMBL; AAFI02000005; EAL71944.1; -; Genomic_DNA.
DR RefSeq; XP_646059.1; XM_640967.1.
DR AlphaFoldDB; P54705; -.
DR SMR; P54705; -.
DR IntAct; P54705; 1.
DR STRING; 44689.DDB0191206; -.
DR PaxDb; P54705; -.
DR PRIDE; P54705; -.
DR EnsemblProtists; EAL71944; EAL71944; DDB_G0269188.
DR GeneID; 8617007; -.
DR KEGG; ddi:DDB_G0269188; -.
DR dictyBase; DDB_G0269188; snwA.
DR eggNOG; KOG2441; Eukaryota.
DR HOGENOM; CLU_006601_2_0_1; -.
DR InParanoid; P54705; -.
DR OMA; WRDSNTL; -.
DR PhylomeDB; P54705; -.
DR Reactome; R-DDI-72163; mRNA Splicing - Major Pathway.
DR PRO; PR:P54705; -.
DR Proteomes; UP000002195; Chromosome 1.
DR GO; GO:0005681; C:spliceosomal complex; IEA:InterPro.
DR GO; GO:0000398; P:mRNA splicing, via spliceosome; IEA:InterPro.
DR InterPro; IPR017862; SKI-int_prot_SKIP.
DR InterPro; IPR004015; SKI-int_prot_SKIP_SNW-dom.
DR PANTHER; PTHR12096; PTHR12096; 2.
DR Pfam; PF02731; SKIP_SNW; 1.
PE 1: Evidence at protein level;
KW Nucleus; Reference proteome.
FT CHAIN 1..685
FT /note="Protein snwA"
FT /id="PRO_0000084826"
FT REGION 1..62
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 88..112
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 194..360
FT /note="SNW"
FT REGION 347..573
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 605..685
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 28..46
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 90..112
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 347..373
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 380..556
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 609..635
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 650..685
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 685 AA; 78530 MW; 1DC8521E9997A583 CRC64;
MTSLSSLLPK PKNVYSNEEE DPLFQPKPKP QQQKQQQQQQ QELNDKPKKV IPTYGNRKGY
LPKNIEDFGD GGAFPEIHIV QYPLDMGRKG KSKSSNSNTS NMNGGGTTTS IVPVSVDSTG
RVKHEAILGE KGSLHSQYKD LIPKQHTEHE LQRPDDDELQ ETLDRTKNAL EKIVNGKIKS
SKSTNYVEVE KKSATYIKYT PSNQLGSNNG SALNSKIVRM VDVAQDPLEP PKYKIKKKIM
EHGSPPAPVM HSPTRKLSVQ DQQDWTIPPC VSNWKNPKGF AISIDKRLVS NGGGLQDVEI
NDKFAHFTQA LYIAESNARE EVSARAELER KLAQKEKERK QDMLRKLAED VRNERSGIIQ
QRYTRKDNSD SDNDNDNDSS SDEDKNKRTP PMNRRSRSRS TERIPSRNDN DDDDDRYRIK
DNRDNRGRDN IDSRDNRDSR DSRDSRDSRD SRDSRDSRDN RDSRDSRDNR DNRDNRRRDD
SNDRDRYSKR RSDSDSDSDS DSSDSEDERV RRERKEKLER DKIRMEKKRE LEREYRLEAS
GKKSKFNRDQ DRDISEKIAL GQASIKRTED SIYDQRLFNQ SESLTSGFGN DDSYNVYSKP
LFGGAVSNSI YRPKSNQEDN TSIQDVLSNS RFGKEGGSGS GGVPRPNKEF SGTDRSKDRT
GPVAFEKEKK KSDDPFGFDD FSKKR
