ID   SNX32_MOUSE             Reviewed;         404 AA.
AC   Q80ZJ7;
DT   26-FEB-2008, integrated into UniProtKB/Swiss-Prot.
DT   01-JUN-2003, sequence version 1.
DT   03-AUG-2022, entry version 115.
DE   RecName: Full=Sorting nexin-32;
DE   AltName: Full=Sorting nexin-6B;
GN   Name=Snx32; Synonyms=Snx6b;
OS   Mus musculus (Mouse).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae;
OC   Murinae; Mus; Mus.
OX   NCBI_TaxID=10090;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   TISSUE=Olfactory epithelium;
RX   PubMed=15489334; DOI=10.1101/gr.2596504;
RG   The MGC Project Team;
RT   "The status, quality, and expansion of the NIH full-length cDNA project:
RT   the Mammalian Gene Collection (MGC).";
RL   Genome Res. 14:2121-2127(2004).
CC   -!- FUNCTION: May be involved in several stages of intracellular
CC       trafficking. {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the sorting nexin family. {ECO:0000305}.
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DR   EMBL; BC048922; AAH48922.1; -; mRNA.
DR   CCDS; CCDS29468.1; -.
DR   RefSeq; NP_001019731.1; NM_001024560.2.
DR   AlphaFoldDB; Q80ZJ7; -.
DR   SMR; Q80ZJ7; -.
DR   STRING; 10090.ENSMUSP00000070915; -.
DR   PhosphoSitePlus; Q80ZJ7; -.
DR   MaxQB; Q80ZJ7; -.
DR   PaxDb; Q80ZJ7; -.
DR   PeptideAtlas; Q80ZJ7; -.
DR   PRIDE; Q80ZJ7; -.
DR   ProteomicsDB; 261302; -.
DR   Antibodypedia; 29952; 131 antibodies from 21 providers.
DR   DNASU; 225861; -.
DR   Ensembl; ENSMUST00000070172; ENSMUSP00000070915; ENSMUSG00000056185.
DR   GeneID; 225861; -.
DR   KEGG; mmu:225861; -.
DR   UCSC; uc008gdr.1; mouse.
DR   CTD; 254122; -.
DR   MGI; MGI:2444704; Snx32.
DR   VEuPathDB; HostDB:ENSMUSG00000056185; -.
DR   eggNOG; KOG1660; Eukaryota.
DR   GeneTree; ENSGT00940000162773; -.
DR   HOGENOM; CLU_040966_0_0_1; -.
DR   InParanoid; Q80ZJ7; -.
DR   OMA; ETHQQLC; -.
DR   OrthoDB; 1009572at2759; -.
DR   PhylomeDB; Q80ZJ7; -.
DR   TreeFam; TF313698; -.
DR   BioGRID-ORCS; 225861; 1 hit in 71 CRISPR screens.
DR   PRO; PR:Q80ZJ7; -.
DR   Proteomes; UP000000589; Chromosome 19.
DR   RNAct; Q80ZJ7; protein.
DR   Bgee; ENSMUSG00000056185; Expressed in superior frontal gyrus and 119 other tissues.
DR   ExpressionAtlas; Q80ZJ7; baseline and differential.
DR   Genevisible; Q80ZJ7; MM.
DR   GO; GO:0005829; C:cytosol; IEA:GOC.
DR   GO; GO:0005768; C:endosome; IBA:GO_Central.
DR   GO; GO:0035091; F:phosphatidylinositol binding; IEA:InterPro.
DR   GO; GO:0015031; P:protein transport; IEA:UniProtKB-KW.
DR   GO; GO:0042147; P:retrograde transport, endosome to Golgi; IBA:GO_Central.
DR   Gene3D; 1.20.1270.60; -; 1.
DR   Gene3D; 3.30.1520.10; -; 1.
DR   InterPro; IPR027267; AH/BAR_dom_sf.
DR   InterPro; IPR001683; PX_dom.
DR   InterPro; IPR036871; PX_dom_sf.
DR   InterPro; IPR014637; SNX5/SNX6/SNX32.
DR   InterPro; IPR015404; Vps5_C.
DR   Pfam; PF00787; PX; 1.
DR   Pfam; PF09325; Vps5; 1.
DR   PIRSF; PIRSF036924; Snx5_Snx6; 1.
DR   SUPFAM; SSF64268; SSF64268; 1.
DR   PROSITE; PS50195; PX; 1.
PE   2: Evidence at transcript level;
KW   Coiled coil; Protein transport; Reference proteome; Transport.
FT   CHAIN           1..404
FT                   /note="Sorting nexin-32"
FT                   /id="PRO_0000320708"
FT   DOMAIN          21..168
FT                   /note="PX"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00147"
FT   REGION          1..29
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COILED          255..336
FT                   /evidence="ECO:0000255"
FT   COMPBIAS        10..25
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   404 AA;  46647 MW;  625FFABF0CF14544 CRC64;
     MEEQHQEAGN ESKPSSTSVD LQGDSPLQVE ISDAVSERDK VKFTVQTKSG LPHFAQSEFS
     VVRQHEEFIW LHDTYVENEE YAGLIIPPAP PRPDFEASRE KLQKLGEGNS SITREEFSKM
     KQELEAEYLA IFKKTVAMHE VFLQRLAAHP TLRRDHNFSV FLEYSQDLSV REKNRKEVLG
     GLLRSIVRSA DEVLITGISG LKEVDDFFEH ERTFLVEYHT RIRDTCQRAD RVMHSHKCLA
     DNYIPISAAL SSLGTQEVNQ LKRSFLKLAE LFERLRKLEG RVASDEDLKL SDMLRYYMRD
     SQAAKDLLYR RLRALADYEN ANKALDKART RNREVRPAES RQQLCCQRFE RLSDSAKQEL
     MDFKSRRVSS FRKNLIELAE LELKHAKAST LLLQNTLVAL KGEP