ID   ABGR_ECOLI              Reviewed;         302 AA.
AC   P77744;
DT   15-JUL-1998, integrated into UniProtKB/Swiss-Prot.
DT   01-FEB-1997, sequence version 1.
DT   03-AUG-2022, entry version 139.
DE   RecName: Full=HTH-type transcriptional regulator AbgR;
GN   Name=abgR; OrderedLocusNames=b1339, JW1333;
OS   Escherichia coli (strain K12).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Enterobacteriaceae; Escherichia.
OX   NCBI_TaxID=83333;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=K12 / W3110 / ATCC 27325 / DSM 5911;
RX   PubMed=9097039; DOI=10.1093/dnares/3.6.363;
RA   Aiba H., Baba T., Fujita K., Hayashi K., Inada T., Isono K., Itoh T.,
RA   Kasai H., Kashimoto K., Kimura S., Kitakawa M., Kitagawa M., Makino K.,
RA   Miki T., Mizobuchi K., Mori H., Mori T., Motomura K., Nakade S.,
RA   Nakamura Y., Nashimoto H., Nishio Y., Oshima T., Saito N., Sampei G.,
RA   Seki Y., Sivasundaram S., Tagami H., Takeda J., Takemoto K., Takeuchi Y.,
RA   Wada C., Yamamoto Y., Horiuchi T.;
RT   "A 570-kb DNA sequence of the Escherichia coli K-12 genome corresponding to
RT   the 28.0-40.1 min region on the linkage map.";
RL   DNA Res. 3:363-377(1996).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=K12 / MG1655 / ATCC 47076;
RX   PubMed=9278503; DOI=10.1126/science.277.5331.1453;
RA   Blattner F.R., Plunkett G. III, Bloch C.A., Perna N.T., Burland V.,
RA   Riley M., Collado-Vides J., Glasner J.D., Rode C.K., Mayhew G.F.,
RA   Gregor J., Davis N.W., Kirkpatrick H.A., Goeden M.A., Rose D.J., Mau B.,
RA   Shao Y.;
RT   "The complete genome sequence of Escherichia coli K-12.";
RL   Science 277:1453-1462(1997).
RN   [3]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=K12 / W3110 / ATCC 27325 / DSM 5911;
RX   PubMed=16738553; DOI=10.1038/msb4100049;
RA   Hayashi K., Morooka N., Yamamoto Y., Fujita K., Isono K., Choi S.,
RA   Ohtsubo E., Baba T., Wanner B.L., Mori H., Horiuchi T.;
RT   "Highly accurate genome sequences of Escherichia coli K-12 strains MG1655
RT   and W3110.";
RL   Mol. Syst. Biol. 2:E1-E5(2006).
RN   [4]
RP   DISRUPTION PHENOTYPE.
RC   STRAIN=BN101;
RX   PubMed=9829935; DOI=10.1128/jb.180.23.6260-6268.1998;
RA   Hussein M.J., Green J.M., Nichols B.P.;
RT   "Characterization of mutations that allow p-aminobenzoyl-glutamate
RT   utilization by Escherichia coli.";
RL   J. Bacteriol. 180:6260-6268(1998).
CC   -!- FUNCTION: Could be the regulator of the abg operon.
CC   -!- DISRUPTION PHENOTYPE: Cells lacking this gene may lead to an altered
CC       expression of abgT. {ECO:0000269|PubMed:9829935}.
CC   -!- SIMILARITY: Belongs to the LysR transcriptional regulatory family.
CC       {ECO:0000305}.
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DR   EMBL; U00096; AAC74421.1; -; Genomic_DNA.
DR   EMBL; AP009048; BAA14941.1; -; Genomic_DNA.
DR   PIR; F64883; F64883.
DR   RefSeq; NP_415855.1; NC_000913.3.
DR   RefSeq; WP_000885458.1; NZ_LN832404.1.
DR   AlphaFoldDB; P77744; -.
DR   SMR; P77744; -.
DR   BioGRID; 4262879; 13.
DR   IntAct; P77744; 2.
DR   STRING; 511145.b1339; -.
DR   PaxDb; P77744; -.
DR   PRIDE; P77744; -.
DR   EnsemblBacteria; AAC74421; AAC74421; b1339.
DR   EnsemblBacteria; BAA14941; BAA14941; BAA14941.
DR   GeneID; 945831; -.
DR   KEGG; ecj:JW1333; -.
DR   KEGG; eco:b1339; -.
DR   PATRIC; fig|1411691.4.peg.938; -.
DR   EchoBASE; EB3136; -.
DR   eggNOG; COG0583; Bacteria.
DR   HOGENOM; CLU_039613_6_0_6; -.
DR   InParanoid; P77744; -.
DR   OMA; WTMPTPR; -.
DR   PhylomeDB; P77744; -.
DR   BioCyc; EcoCyc:G6671-MON; -.
DR   PRO; PR:P77744; -.
DR   Proteomes; UP000000318; Chromosome.
DR   Proteomes; UP000000625; Chromosome.
DR   GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:InterPro.
DR   GO; GO:0000976; F:transcription cis-regulatory region binding; IBA:GO_Central.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IBA:GO_Central.
DR   Gene3D; 1.10.10.10; -; 1.
DR   InterPro; IPR005119; LysR_subst-bd.
DR   InterPro; IPR000847; Tscrpt_reg_HTH_LysR.
DR   InterPro; IPR036388; WH-like_DNA-bd_sf.
DR   InterPro; IPR036390; WH_DNA-bd_sf.
DR   Pfam; PF00126; HTH_1; 1.
DR   Pfam; PF03466; LysR_substrate; 1.
DR   PRINTS; PR00039; HTHLYSR.
DR   SUPFAM; SSF46785; SSF46785; 1.
DR   PROSITE; PS50931; HTH_LYSR; 1.
PE   3: Inferred from homology;
KW   DNA-binding; Reference proteome; Transcription; Transcription regulation.
FT   CHAIN           1..302
FT                   /note="HTH-type transcriptional regulator AbgR"
FT                   /id="PRO_0000105583"
FT   DOMAIN          5..62
FT                   /note="HTH lysR-type"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00253"
FT   DNA_BIND        22..41
FT                   /note="H-T-H motif"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00253"
SQ   SEQUENCE   302 AA;  34058 MW;  57C83FA6DF8ABA66 CRC64;
     MAFQVKIHQI RAFVEVARQG SIRGASRMLN MSQPALSKSI QELEEGLAAQ LFFRRSKGVT
     LTDAGESFYQ HASLILEELR AAQEDIRQRQ GQLAGQINIG MGASISRSLM PAVISRFHQQ
     HPQVKVRIME GQLVSMINEL RQGELDFTIN TYYQGPYDHE FTFEKLLEKQ FAIFCRPGHP
     AIGARSIKQL LDYSWTMPTP HGSYYKQLSE LLDDQAQTPQ VGVVCETFSA CISLVAKSDF
     LSKLPEEMGC DPLHGQGLVM LPVSEILPKA AYYLIQRRDS RQTPLTASLI TQFRRECGYL
     QS