SOBRL_ARATH
ID SOBRL_ARATH Reviewed; 262 AA.
AC Q8GYK2; A4KWB1;
DT 24-JUN-2015, integrated into UniProtKB/Swiss-Prot.
DT 01-MAR-2003, sequence version 1.
DT 03-AUG-2022, entry version 106.
DE RecName: Full=Probable carboxylesterase SOBER1-like {ECO:0000305};
DE EC=3.1.1.- {ECO:0000305};
GN OrderedLocusNames=At4g22300 {ECO:0000312|Araport:AT4G22300};
GN ORFNames=T10I14_130 {ECO:0000312|EMBL:AL021712};
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=10617198; DOI=10.1038/47134;
RA Mayer K.F.X., Schueller C., Wambutt R., Murphy G., Volckaert G., Pohl T.,
RA Duesterhoeft A., Stiekema W., Entian K.-D., Terryn N., Harris B.,
RA Ansorge W., Brandt P., Grivell L.A., Rieger M., Weichselgartner M.,
RA de Simone V., Obermaier B., Mache R., Mueller M., Kreis M., Delseny M.,
RA Puigdomenech P., Watson M., Schmidtheini T., Reichert B., Portetelle D.,
RA Perez-Alonso M., Boutry M., Bancroft I., Vos P., Hoheisel J.,
RA Zimmermann W., Wedler H., Ridley P., Langham S.-A., McCullagh B.,
RA Bilham L., Robben J., van der Schueren J., Grymonprez B., Chuang Y.-J.,
RA Vandenbussche F., Braeken M., Weltjens I., Voet M., Bastiaens I., Aert R.,
RA Defoor E., Weitzenegger T., Bothe G., Ramsperger U., Hilbert H., Braun M.,
RA Holzer E., Brandt A., Peters S., van Staveren M., Dirkse W., Mooijman P.,
RA Klein Lankhorst R., Rose M., Hauf J., Koetter P., Berneiser S., Hempel S.,
RA Feldpausch M., Lamberth S., Van den Daele H., De Keyser A., Buysshaert C.,
RA Gielen J., Villarroel R., De Clercq R., van Montagu M., Rogers J.,
RA Cronin A., Quail M.A., Bray-Allen S., Clark L., Doggett J., Hall S.,
RA Kay M., Lennard N., McLay K., Mayes R., Pettett A., Rajandream M.A.,
RA Lyne M., Benes V., Rechmann S., Borkova D., Bloecker H., Scharfe M.,
RA Grimm M., Loehnert T.-H., Dose S., de Haan M., Maarse A.C., Schaefer M.,
RA Mueller-Auer S., Gabel C., Fuchs M., Fartmann B., Granderath K., Dauner D.,
RA Herzl A., Neumann S., Argiriou A., Vitale D., Liguori R., Piravandi E.,
RA Massenet O., Quigley F., Clabauld G., Muendlein A., Felber R., Schnabl S.,
RA Hiller R., Schmidt W., Lecharny A., Aubourg S., Chefdor F., Cooke R.,
RA Berger C., Monfort A., Casacuberta E., Gibbons T., Weber N., Vandenbol M.,
RA Bargues M., Terol J., Torres A., Perez-Perez A., Purnelle B., Bent E.,
RA Johnson S., Tacon D., Jesse T., Heijnen L., Schwarz S., Scholler P.,
RA Heber S., Francs P., Bielke C., Frishman D., Haase D., Lemcke K.,
RA Mewes H.-W., Stocker S., Zaccaria P., Bevan M., Wilson R.K.,
RA de la Bastide M., Habermann K., Parnell L., Dedhia N., Gnoj L., Schutz K.,
RA Huang E., Spiegel L., Sekhon M., Murray J., Sheet P., Cordes M.,
RA Abu-Threideh J., Stoneking T., Kalicki J., Graves T., Harmon G.,
RA Edwards J., Latreille P., Courtney L., Cloud J., Abbott A., Scott K.,
RA Johnson D., Minx P., Bentley D., Fulton B., Miller N., Greco T., Kemp K.,
RA Kramer J., Fulton L., Mardis E., Dante M., Pepin K., Hillier L.W.,
RA Nelson J., Spieth J., Ryan E., Andrews S., Geisel C., Layman D., Du H.,
RA Ali J., Berghoff A., Jones K., Drone K., Cotton M., Joshu C., Antonoiu B.,
RA Zidanic M., Strong C., Sun H., Lamar B., Yordan C., Ma P., Zhong J.,
RA Preston R., Vil D., Shekher M., Matero A., Shah R., Swaby I.K.,
RA O'Shaughnessy A., Rodriguez M., Hoffman J., Till S., Granat S., Shohdy N.,
RA Hasegawa A., Hameed A., Lodhi M., Johnson A., Chen E., Marra M.A.,
RA Martienssen R., McCombie W.R.;
RT "Sequence and analysis of chromosome 4 of the plant Arabidopsis thaliana.";
RL Nature 402:769-777(1999).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Columbia;
RX PubMed=11910074; DOI=10.1126/science.1071006;
RA Seki M., Narusaka M., Kamiya A., Ishida J., Satou M., Sakurai T.,
RA Nakajima M., Enju A., Akiyama K., Oono Y., Muramatsu M., Hayashizaki Y.,
RA Kawai J., Carninci P., Itoh M., Ishii Y., Arakawa T., Shibata K.,
RA Shinagawa A., Shinozaki K.;
RT "Functional annotation of a full-length Arabidopsis cDNA collection.";
RL Science 296:141-145(2002).
RN [4]
RP NUCLEOTIDE SEQUENCE [MRNA] OF 46-262.
RC STRAIN=cv. Columbia;
RX PubMed=17293566; DOI=10.1105/tpc.106.048710;
RA Cunnac S., Wilson A., Nuwer J., Kirik A., Baranage G., Mudgett M.B.;
RT "A conserved carboxylesterase is a SUPPRESSOR OF AVRBST-ELICITED RESISTANCE
RT in Arabidopsis.";
RL Plant Cell 19:688-705(2007).
CC -!- FUNCTION: Carboxylesterase. {ECO:0000250|UniProtKB:Q84WK4}.
CC -!- SIMILARITY: Belongs to the AB hydrolase superfamily. AB hydrolase 2
CC family. {ECO:0000305}.
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DR EMBL; AL021712; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; CP002687; AEE84589.1; -; Genomic_DNA.
DR EMBL; AK117563; BAC42224.1; -; mRNA.
DR EMBL; EF100726; ABO26814.1; -; mRNA.
DR RefSeq; NP_193961.3; NM_118356.4.
DR AlphaFoldDB; Q8GYK2; -.
DR SMR; Q8GYK2; -.
DR STRING; 3702.AT4G22300.1; -.
DR ESTHER; arath-SOBRL; LYsophospholipase_carboxylesterase.
DR PaxDb; Q8GYK2; -.
DR PRIDE; Q8GYK2; -.
DR ProteomicsDB; 245324; -.
DR EnsemblPlants; AT4G22300.1; AT4G22300.1; AT4G22300.
DR GeneID; 828325; -.
DR Gramene; AT4G22300.1; AT4G22300.1; AT4G22300.
DR KEGG; ath:AT4G22300; -.
DR Araport; AT4G22300; -.
DR TAIR; locus:2132085; AT4G22300.
DR eggNOG; KOG2112; Eukaryota.
DR HOGENOM; CLU_049413_1_0_1; -.
DR InParanoid; Q8GYK2; -.
DR OMA; LEYPHIK; -.
DR OrthoDB; 1373549at2759; -.
DR BioCyc; ARA:AT4G22300-MON; -.
DR PRO; PR:Q8GYK2; -.
DR Proteomes; UP000006548; Chromosome 4.
DR ExpressionAtlas; Q8GYK2; baseline and differential.
DR Genevisible; Q8GYK2; AT.
DR GO; GO:0005737; C:cytoplasm; IBA:GO_Central.
DR GO; GO:0005886; C:plasma membrane; IDA:TAIR.
DR GO; GO:0052689; F:carboxylic ester hydrolase activity; IBA:GO_Central.
DR GO; GO:0008474; F:palmitoyl-(protein) hydrolase activity; IBA:GO_Central.
DR GO; GO:0006631; P:fatty acid metabolic process; IEA:UniProtKB-KW.
DR GO; GO:0002084; P:protein depalmitoylation; IBA:GO_Central.
DR Gene3D; 3.40.50.1820; -; 1.
DR InterPro; IPR029058; AB_hydrolase.
DR InterPro; IPR003140; PLipase/COase/thioEstase.
DR Pfam; PF02230; Abhydrolase_2; 1.
DR SUPFAM; SSF53474; SSF53474; 1.
PE 2: Evidence at transcript level;
KW Fatty acid metabolism; Hydrolase; Lipid metabolism; Reference proteome.
FT CHAIN 1..262
FT /note="Probable carboxylesterase SOBER1-like"
FT /id="PRO_0000433447"
FT ACT_SITE 151
FT /note="Charge relay system"
FT /evidence="ECO:0000250|UniProtKB:O75608"
FT ACT_SITE 205
FT /note="Charge relay system"
FT /evidence="ECO:0000250|UniProtKB:O75608"
FT ACT_SITE 237
FT /note="Charge relay system"
FT /evidence="ECO:0000250|UniProtKB:O75608"
FT CONFLICT 161
FT /note="V -> F (in Ref. 4; ABO26814)"
FT /evidence="ECO:0000305"
SQ SEQUENCE 262 AA; 28703 MW; 5E2D45D9E39D4970 CRC64;
MRTSRLKKPI VLLTIALLSS VFFFAFFFLN KSDVSSTSAL RNRDSMARTF ILWLHGLGDS
GPANEPIKTL FRSQEFRNTK WLFPSAPPNP VSCNYGAVMP SWFDIPELPL TAGSPKDESS
LLKAVKNVHA IIDKEIAGGI NPENVYICGF SQGGALTLAS VLLYPKTIGG GAVFSGWIPF
NSSITNQFTE DAKKTPILWS HGIDDKTVLF EAGQAALPFL QQAGVTCEFK AYPGLGHSIS
NEELQYLESW LKQRMQSSSS SS
