ID   SODC2_DEBHN             Reviewed;          52 AA.
AC   P82902;
DT   26-SEP-2001, integrated into UniProtKB/Swiss-Prot.
DT   26-SEP-2001, sequence version 1.
DT   03-AUG-2022, entry version 75.
DE   RecName: Full=Superoxide dismutase [Cu-Zn] 2;
DE            EC=1.15.1.1 {ECO:0000250|UniProtKB:P85978};
DE   Flags: Fragments;
OS   Debaryomyces hansenii (Yeast) (Torulaspora hansenii).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC   Saccharomycetales; Debaryomycetaceae; Debaryomyces.
OX   NCBI_TaxID=4959;
RN   [1]
RP   PROTEIN SEQUENCE.
RC   STRAIN=CIBNOR C-11;
RA   Hernandez-Saavedra N.Y.;
RT   "Presence of two active forms of cytosolic Cu-Zn superoxide dismutase
RT   enzyme in the marine yeast Debaryomyces hansenii.";
RL   Submitted (DEC-2000) to UniProtKB.
CC   -!- FUNCTION: Destroys radicals which are normally produced within the
CC       cells and which are toxic to biological systems.
CC       {ECO:0000250|UniProtKB:P00442}.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=2 H(+) + 2 superoxide = H2O2 + O2; Xref=Rhea:RHEA:20696,
CC         ChEBI:CHEBI:15378, ChEBI:CHEBI:15379, ChEBI:CHEBI:16240,
CC         ChEBI:CHEBI:18421; EC=1.15.1.1;
CC         Evidence={ECO:0000250|UniProtKB:P85978};
CC   -!- COFACTOR:
CC       Name=Cu cation; Xref=ChEBI:CHEBI:23378;
CC         Evidence={ECO:0000250|UniProtKB:P00445};
CC       Note=Binds 1 copper ion per subunit. {ECO:0000250|UniProtKB:P00445};
CC   -!- COFACTOR:
CC       Name=Zn(2+); Xref=ChEBI:CHEBI:29105;
CC         Evidence={ECO:0000250|UniProtKB:P00445};
CC       Note=Binds 1 zinc ion per subunit. {ECO:0000250|UniProtKB:P00445};
CC   -!- SUBUNIT: Homodimer. {ECO:0000250|UniProtKB:P85978}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250|UniProtKB:P00445}.
CC   -!- SIMILARITY: Belongs to the Cu-Zn superoxide dismutase family.
CC       {ECO:0000305}.
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DR   AlphaFoldDB; P82902; -.
DR   SMR; P82902; -.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0004784; F:superoxide dismutase activity; IEA:UniProtKB-EC.
DR   InterPro; IPR036423; SOD-like_Cu/Zn_dom_sf.
DR   SUPFAM; SSF49329; SSF49329; 1.
PE   1: Evidence at protein level;
KW   Antioxidant; Copper; Cytoplasm; Direct protein sequencing; Metal-binding;
KW   Oxidoreductase; Zinc.
FT   CHAIN           <1..>52
FT                   /note="Superoxide dismutase [Cu-Zn] 2"
FT                   /id="PRO_0000164119"
FT   BINDING         44
FT                   /ligand="Cu cation"
FT                   /ligand_id="ChEBI:CHEBI:23378"
FT                   /ligand_note="catalytic"
FT                   /evidence="ECO:0000250|UniProtKB:P00445"
FT   NON_CONS        29..30
FT                   /evidence="ECO:0000305"
FT   NON_TER         1
FT   NON_TER         52
SQ   SEQUENCE   52 AA;  5555 MW;  830DA15280D25708 CRC64;
     KAVAVLRGDS NVSGVVRFEQ THESEPTKIF IGQNSILALT VVVHAGTDDY GK