ABGX_LACLC
ID ABGX_LACLC Reviewed; 232 AA.
AC Q48724;
DT 02-NOV-2001, integrated into UniProtKB/Swiss-Prot.
DT 01-NOV-1996, sequence version 1.
DT 25-MAY-2022, entry version 60.
DE RecName: Full=UPF0177 protein in abiGi 5'region;
DE AltName: Full=orfX;
OS Lactococcus lactis subsp. cremoris (Streptococcus cremoris).
OG Plasmid pCI750.
OC Bacteria; Firmicutes; Bacilli; Lactobacillales; Streptococcaceae;
OC Lactococcus.
OX NCBI_TaxID=1359;
RN [1]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC STRAIN=UC653;
RX PubMed=8795193; DOI=10.1128/aem.62.9.3075-3082.1996;
RA O'Connor L., Coffey A., Daly C., Fitzgerald G.F.;
RT "AbiG, a genotypically novel abortive infection mechanism encoded by
RT plasmid pCI750 of Lactococcus lactis subsp. cremoris UC653.";
RL Appl. Environ. Microbiol. 62:3075-3082(1996).
CC -!- FUNCTION: The function of this protein is currently unknown, but it has
CC been shown that it is not necessary for phage resistance.
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000305}; Multi-pass membrane
CC protein {ECO:0000305}.
CC -!- SIMILARITY: Belongs to the UPF0177 family. {ECO:0000305}.
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DR EMBL; U60336; AAB38311.1; -; Genomic_DNA.
DR RefSeq; WP_015081755.1; NZ_WJUX01000040.1.
DR AlphaFoldDB; Q48724; -.
DR SMR; Q48724; -.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0004222; F:metalloendopeptidase activity; IEA:InterPro.
DR GO; GO:0071586; P:CAAX-box protein processing; IEA:InterPro.
DR InterPro; IPR003675; Rce1-like.
DR Pfam; PF02517; Rce1-like; 1.
PE 3: Inferred from homology;
KW Cell membrane; Membrane; Plasmid; Transmembrane; Transmembrane helix.
FT CHAIN 1..232
FT /note="UPF0177 protein in abiGi 5'region"
FT /id="PRO_0000220574"
FT TRANSMEM 12..32
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 47..67
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 86..106
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 124..144
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 165..185
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 206..226
FT /note="Helical"
FT /evidence="ECO:0000255"
SQ SEQUENCE 232 AA; 26967 MW; 6E063C908118CFF3 CRC64;
MIKNHWMKKL KYLSLFFLLF AIYWFPDVIL AYPEVYLKSL VGYERQVVAT WIFLGNMSIS
LFLGILICYK LGYYKNTISI FKIKNLLFLL ITTIILFVIY FFSYTYYNSH FITPGIAKTQ
AAFSIQIVFP FVQFITIAIC APIFEEASFR TTIYSFFKND KIAYIVSCVG FAWMHTGPNP
ILIVYLPMSI VLTSIYHRRR VLGESILVHG VFNALLPIVI PLLQVITGLY YL