ID   SODF_NICPL              Reviewed;         202 AA.
AC   P22302;
DT   01-AUG-1991, integrated into UniProtKB/Swiss-Prot.
DT   01-AUG-1991, sequence version 1.
DT   03-AUG-2022, entry version 99.
DE   RecName: Full=Superoxide dismutase [Fe], chloroplastic;
DE            EC=1.15.1.1;
DE   Flags: Fragment;
GN   Name=SODB;
OS   Nicotiana plumbaginifolia (Leadwort-leaved tobacco) (Tex-Mex tobacco).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC   asterids; lamiids; Solanales; Solanaceae; Nicotianoideae; Nicotianeae;
OC   Nicotiana.
OX   NCBI_TaxID=4092;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [MRNA].
RC   STRAIN=cv. P2;
RX   PubMed=2263641; DOI=10.1073/pnas.87.24.9903;
RA   van Camp W., Bowler C., Villarroel R., Tsang E.W.T., van Montagu M.,
RA   Inze D.;
RT   "Characterization of iron superoxide dismutase cDNAs from plants obtained
RT   by genetic complementation in Escherichia coli.";
RL   Proc. Natl. Acad. Sci. U.S.A. 87:9903-9907(1990).
CC   -!- FUNCTION: Destroys superoxide anion radicals which are normally
CC       produced within the cells and which are toxic to biological systems.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=2 H(+) + 2 superoxide = H2O2 + O2; Xref=Rhea:RHEA:20696,
CC         ChEBI:CHEBI:15378, ChEBI:CHEBI:15379, ChEBI:CHEBI:16240,
CC         ChEBI:CHEBI:18421; EC=1.15.1.1;
CC   -!- COFACTOR:
CC       Name=Fe cation; Xref=ChEBI:CHEBI:24875; Evidence={ECO:0000250};
CC       Note=Binds 1 Fe cation per subunit. {ECO:0000250};
CC   -!- SUBUNIT: Homodimer.
CC   -!- SUBCELLULAR LOCATION: Plastid, chloroplast.
CC   -!- INDUCTION: By environmental conditions.
CC   -!- SIMILARITY: Belongs to the iron/manganese superoxide dismutase family.
CC       {ECO:0000305}.
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DR   EMBL; M55909; AAA34074.1; -; mRNA.
DR   AlphaFoldDB; P22302; -.
DR   SMR; P22302; -.
DR   BRENDA; 1.15.1.1; 3640.
DR   GO; GO:0009507; C:chloroplast; IEA:UniProtKB-SubCell.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0004784; F:superoxide dismutase activity; IEA:UniProtKB-EC.
DR   Gene3D; 1.10.287.990; -; 1.
DR   Gene3D; 3.55.40.20; -; 1.
DR   InterPro; IPR001189; Mn/Fe_SOD.
DR   InterPro; IPR019833; Mn/Fe_SOD_BS.
DR   InterPro; IPR019832; Mn/Fe_SOD_C.
DR   InterPro; IPR019831; Mn/Fe_SOD_N.
DR   InterPro; IPR036324; Mn/Fe_SOD_N_sf.
DR   InterPro; IPR036314; SOD_C_sf.
DR   Pfam; PF02777; Sod_Fe_C; 1.
DR   Pfam; PF00081; Sod_Fe_N; 1.
DR   PIRSF; PIRSF000349; SODismutase; 1.
DR   PRINTS; PR01703; MNSODISMTASE.
DR   SUPFAM; SSF46609; SSF46609; 1.
DR   SUPFAM; SSF54719; SSF54719; 1.
DR   PROSITE; PS00088; SOD_MN; 1.
PE   2: Evidence at transcript level;
KW   Chloroplast; Iron; Metal-binding; Oxidoreductase; Plastid.
FT   CHAIN           <1..202
FT                   /note="Superoxide dismutase [Fe], chloroplastic"
FT                   /id="PRO_0000159968"
FT   BINDING         26
FT                   /ligand="Fe cation"
FT                   /ligand_id="ChEBI:CHEBI:24875"
FT                   /evidence="ECO:0000250"
FT   BINDING         78
FT                   /ligand="Fe cation"
FT                   /ligand_id="ChEBI:CHEBI:24875"
FT                   /evidence="ECO:0000250"
FT   BINDING         162
FT                   /ligand="Fe cation"
FT                   /ligand_id="ChEBI:CHEBI:24875"
FT                   /evidence="ECO:0000250"
FT   BINDING         166
FT                   /ligand="Fe cation"
FT                   /ligand_id="ChEBI:CHEBI:24875"
FT                   /evidence="ECO:0000250"
FT   NON_TER         1
SQ   SEQUENCE   202 AA;  23042 MW;  869E79BDD0302C27 CRC64;
     KFELQPPPYP MDALEPHMSS RTFEFHWGKH HRAYVDNLNK QIDGTELDGK TLEDIILVTY
     NKGAPLPAFN NAAQAWNHQF FWESMKPNGG GEPSGELLEL INRDFGSYDA FVKEFKAAAA
     TQFGSGWAWL AYKPEEKKLA LVKTPNAENP LVLGYTPLLT IDVWEHAYYL DFQNRRPDYI
     SIFMEKLVSW EAVSSRLKAA TA