ID   SODL_VACCW              Reviewed;         125 AA.
AC   P26669; Q76ZN2;
DT   01-AUG-1992, integrated into UniProtKB/Swiss-Prot.
DT   01-AUG-1992, sequence version 1.
DT   23-FEB-2022, entry version 101.
DE   RecName: Full=Cu-Zn superoxide dismutase-like protein A45R;
GN   OrderedLocusNames=VACWR171; ORFNames=SALF8R;
OS   Vaccinia virus (strain Western Reserve) (VACV) (Vaccinia virus (strain
OS   WR)).
OC   Viruses; Varidnaviria; Bamfordvirae; Nucleocytoviricota; Pokkesviricetes;
OC   Chitovirales; Poxviridae; Chordopoxvirinae; Orthopoxvirus; Vaccinia virus.
OX   NCBI_TaxID=10254;
OH   NCBI_TaxID=9913; Bos taurus (Bovine).
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX   PubMed=1870190; DOI=10.1128/jvi.65.9.4598-4608.1991;
RA   Blasco R., Cole N.B., Moss B.;
RT   "Sequence analysis, expression, and deletion of a vaccinia virus gene
RT   encoding a homolog of profilin, a eukaryotic actin-binding protein.";
RL   J. Virol. 65:4598-4608(1991).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX   PubMed=2045793; DOI=10.1099/0022-1317-72-6-1349;
RA   Smith G.L., Chan Y.S., Howard S.T.;
RT   "Nucleotide sequence of 42 kbp of vaccinia virus strain WR from near the
RT   right inverted terminal repeat.";
RL   J. Gen. Virol. 72:1349-1376(1991).
RN   [3]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA   Esposito J.J., Frace A.M., Sammons S.A., Olsen-Rasmussen M., Osborne J.,
RA   Wohlhueter R.;
RT   "Sequencing of the coding region of Vaccinia-WR to an average 9-fold
RT   redundancy and an error rate of 0.16/10kb.";
RL   Submitted (FEB-2003) to the EMBL/GenBank/DDBJ databases.
RN   [4]
RP   FUNCTION.
RX   PubMed=11435582; DOI=10.1128/jvi.75.15.7018-7029.2001;
RA   Almazan F., Tscharke D.C., Smith G.L.;
RT   "The vaccinia virus superoxide dismutase-like protein (A45R) is a virion
RT   component that is nonessential for virus replication.";
RL   J. Virol. 75:7018-7029(2001).
CC   -!- FUNCTION: Superoxide dismutase-like protein with no enzymatic activity.
CC       {ECO:0000269|PubMed:11435582}.
CC   -!- SUBCELLULAR LOCATION: Virion. Host cytoplasm. Note=Accumulates
CC       predominantly in cytoplasmic viral factories.
CC   -!- SIMILARITY: Belongs to the Cu-Zn superoxide dismutase family.
CC       {ECO:0000305}.
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DR   EMBL; M72474; AAA48312.1; -; Genomic_DNA.
DR   EMBL; D11079; BAA01819.1; -; Genomic_DNA.
DR   EMBL; AY243312; AAO89450.1; -; Genomic_DNA.
DR   PIR; F40897; DSVZCR.
DR   RefSeq; YP_233053.1; NC_006998.1.
DR   SMR; P26669; -.
DR   DIP; DIP-2172N; -.
DR   IntAct; P26669; 2.
DR   MINT; P26669; -.
DR   DNASU; 3707701; -.
DR   GeneID; 3707701; -.
DR   KEGG; vg:3707701; -.
DR   Proteomes; UP000000344; Genome.
DR   GO; GO:0030430; C:host cell cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0046872; F:metal ion binding; IEA:InterPro.
DR   GO; GO:0006801; P:superoxide metabolic process; IEA:InterPro.
DR   Gene3D; 2.60.40.200; -; 1.
DR   InterPro; IPR036423; SOD-like_Cu/Zn_dom_sf.
DR   SUPFAM; SSF49329; SSF49329; 1.
PE   3: Inferred from homology;
KW   Disulfide bond; Host cytoplasm; Reference proteome; Virion.
FT   CHAIN           1..125
FT                   /note="Cu-Zn superoxide dismutase-like protein A45R"
FT                   /id="PRO_0000164169"
FT   DISULFID        52..102
FT                   /evidence="ECO:0000250"
SQ   SEQUENCE   125 AA;  13663 MW;  9DD9320C2B6004CD CRC64;
     MAVCIIDHDN IRGVIYFEPV HGKDKVLGSV IGLKSGTYSL IIHRYGDISQ GCDSIGSPEI
     FIGNIFVNRY GVAYVYLDTD VNISTIIGKA LSISKNDQRL ACGVIGISYI NEKIIHFLTI
     NENGV