ID   SODL_VARV               Reviewed;         125 AA.
AC   P0DTA2; P33805; Q76PV6;
DT   16-OCT-2019, integrated into UniProtKB/Swiss-Prot.
DT   16-OCT-2019, sequence version 1.
DT   29-SEP-2021, entry version 11.
DE   RecName: Full=Cu-Zn superoxide dismutase-like protein;
GN   ORFNames=A45R, A51R, A55R;
OS   Variola virus.
OC   Viruses; Varidnaviria; Bamfordvirae; Nucleocytoviricota; Pokkesviricetes;
OC   Chitovirales; Poxviridae; Chordopoxvirinae; Orthopoxvirus.
OX   NCBI_TaxID=10255;
OH   NCBI_TaxID=9606; Homo sapiens (Human).
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=Harvey;
RX   PubMed=1331292; DOI=10.1099/0022-1317-73-11-2887;
RA   Aguado B., Selmes I.P., Smith G.L.;
RT   "Nucleotide sequence of 21.8 kbp of variola major virus strain Harvey and
RT   comparison with vaccinia virus.";
RL   J. Gen. Virol. 73:2887-2902(1992).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=Bangladesh-1975;
RX   PubMed=8264798; DOI=10.1038/366748a0;
RA   Massung R.F., Esposito J.J., Liu L.I., Qi J., Utterback T.R., Knight J.C.,
RA   Aubin L., Yuran T.E., Parsons J.M., Loparev V.N., Selivanov N.A.,
RA   Cavallaro K.F., Kerlavage A.R., Mahy B.W.J., Venter J.C.;
RT   "Potential virulence determinants in terminal regions of variola smallpox
RT   virus genome.";
RL   Nature 366:748-751(1993).
RN   [3]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Garcia-1966;
RX   PubMed=10639322; DOI=10.1006/viro.1999.0086;
RA   Shchelkunov S.N., Totmenin A.V., Loparev V.N., Safronov P.F., Gutorov V.V.,
RA   Chizhikov V.E., Knight J.C., Parsons J.M., Massung R.F., Esposito J.J.;
RT   "Alastrim smallpox variola minor virus genome DNA sequences.";
RL   Virology 266:361-386(2000).
CC   -!- FUNCTION: Superoxide dismutase-like protein with no enzymatic activity.
CC       {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Virion. Host cytoplasm. Note=Accumulates
CC       predominantly in cytoplasmic viral factories. {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the Cu-Zn superoxide dismutase family.
CC       {ECO:0000305}.
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DR   EMBL; L22579; AAA60900.1; -; Genomic_DNA.
DR   EMBL; Y16780; CAB54758.1; -; Genomic_DNA.
DR   PIR; D72170; D72170.
DR   RefSeq; NP_042201.1; NC_001611.1.
DR   SMR; P0DTA2; -.
DR   GeneID; 1486533; -.
DR   KEGG; vg:1486533; -.
DR   Proteomes; UP000111493; Genome.
DR   Proteomes; UP000119805; Genome.
DR   GO; GO:0030430; C:host cell cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0046872; F:metal ion binding; IEA:InterPro.
DR   GO; GO:0006801; P:superoxide metabolic process; IEA:InterPro.
DR   Gene3D; 2.60.40.200; -; 1.
DR   InterPro; IPR036423; SOD-like_Cu/Zn_dom_sf.
DR   SUPFAM; SSF49329; SSF49329; 1.
PE   3: Inferred from homology;
KW   Disulfide bond; Host cytoplasm; Virion.
FT   CHAIN           1..125
FT                   /note="Cu-Zn superoxide dismutase-like protein"
FT                   /id="PRO_0000448127"
FT   DISULFID        52..102
FT                   /evidence="ECO:0000250"
SQ   SEQUENCE   125 AA;  13717 MW;  A4325D1B800D12CE CRC64;
     MAVCIIDHDN IRGVIYFEPV HGKDKVLGSV IGLKSGTYNL IIHRYGDISR GCNSIGSPEI
     FIGNIFVNRY GVAYVYLDTD VNISTIIGKA LSISKNDQRL ACGVIGISYI NEKIIHFLTI
     NENGV