ID   SODM_MYCSI              Reviewed;          18 AA.
AC   P80582;
DT   01-OCT-1996, integrated into UniProtKB/Swiss-Prot.
DT   01-OCT-1996, sequence version 1.
DT   25-MAY-2022, entry version 56.
DE   RecName: Full=Superoxide dismutase [Mn];
DE            EC=1.15.1.1;
DE   Flags: Fragment;
GN   Name=sodA; Synonyms=sod;
OS   Mycobacterium simiae (Mycobacterium habana).
OC   Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
OC   Mycobacterium; Mycobacterium simiae complex.
OX   NCBI_TaxID=1784;
RN   [1]
RP   PROTEIN SEQUENCE.
RC   STRAIN=TMC 5135;
RX   PubMed=8704977; DOI=10.1099/13500872-142-6-1375;
RA   Bisht D., Mehrotra J., Dhindsa M.S., Singh N.B., Sinha S.;
RT   "A major T-cell-inducing cytosolic 23 kDa protein antigen of the vaccine
RT   candidate Mycobacterium habana is superoxide dismutase.";
RL   Microbiology 142:1375-1383(1996).
CC   -!- FUNCTION: Destroys superoxide anion radicals which are normally
CC       produced within the cells and which are toxic to biological systems.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=2 H(+) + 2 superoxide = H2O2 + O2; Xref=Rhea:RHEA:20696,
CC         ChEBI:CHEBI:15378, ChEBI:CHEBI:15379, ChEBI:CHEBI:16240,
CC         ChEBI:CHEBI:18421; EC=1.15.1.1;
CC   -!- COFACTOR:
CC       Name=Mn(2+); Xref=ChEBI:CHEBI:29035; Evidence={ECO:0000250};
CC       Note=Binds 1 Mn(2+) ion per subunit. {ECO:0000250};
CC   -!- SUBUNIT: Homodimer. {ECO:0000305}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm.
CC   -!- SIMILARITY: Belongs to the iron/manganese superoxide dismutase family.
CC       {ECO:0000305}.
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DR   AlphaFoldDB; P80582; -.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0004784; F:superoxide dismutase activity; IEA:UniProtKB-EC.
PE   1: Evidence at protein level;
KW   Cytoplasm; Direct protein sequencing; Manganese; Metal-binding;
KW   Oxidoreductase.
FT   CHAIN           1..>18
FT                   /note="Superoxide dismutase [Mn]"
FT                   /id="PRO_0000160049"
FT   NON_TER         18
SQ   SEQUENCE   18 AA;  1883 MW;  A4161A3DAC93F710 CRC64;
     AEYTLPDLGW DYAASGPG