SOG2_SCHPO
ID SOG2_SCHPO Reviewed; 886 AA.
AC O94294;
DT 04-DEC-2007, integrated into UniProtKB/Swiss-Prot.
DT 01-MAY-1999, sequence version 1.
DT 25-MAY-2022, entry version 120.
DE RecName: Full=Leucine-rich repeat-containing protein sog2;
GN Name=sog2 {ECO:0000250|UniProtKB:Q08817}; ORFNames=SPBC887.09c;
OS Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina;
OC Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae;
OC Schizosaccharomyces.
OX NCBI_TaxID=284812;
RN [1] {ECO:0000312|EMBL:CAA21894.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=972 / ATCC 24843;
RX PubMed=11859360; DOI=10.1038/nature724;
RA Wood V., Gwilliam R., Rajandream M.A., Lyne M.H., Lyne R., Stewart A.,
RA Sgouros J.G., Peat N., Hayles J., Baker S.G., Basham D., Bowman S.,
RA Brooks K., Brown D., Brown S., Chillingworth T., Churcher C.M., Collins M.,
RA Connor R., Cronin A., Davis P., Feltwell T., Fraser A., Gentles S.,
RA Goble A., Hamlin N., Harris D.E., Hidalgo J., Hodgson G., Holroyd S.,
RA Hornsby T., Howarth S., Huckle E.J., Hunt S., Jagels K., James K.D.,
RA Jones L., Jones M., Leather S., McDonald S., McLean J., Mooney P.,
RA Moule S., Mungall K.L., Murphy L.D., Niblett D., Odell C., Oliver K.,
RA O'Neil S., Pearson D., Quail M.A., Rabbinowitsch E., Rutherford K.M.,
RA Rutter S., Saunders D., Seeger K., Sharp S., Skelton J., Simmonds M.N.,
RA Squares R., Squares S., Stevens K., Taylor K., Taylor R.G., Tivey A.,
RA Walsh S.V., Warren T., Whitehead S., Woodward J.R., Volckaert G., Aert R.,
RA Robben J., Grymonprez B., Weltjens I., Vanstreels E., Rieger M.,
RA Schaefer M., Mueller-Auer S., Gabel C., Fuchs M., Duesterhoeft A.,
RA Fritzc C., Holzer E., Moestl D., Hilbert H., Borzym K., Langer I., Beck A.,
RA Lehrach H., Reinhardt R., Pohl T.M., Eger P., Zimmermann W., Wedler H.,
RA Wambutt R., Purnelle B., Goffeau A., Cadieu E., Dreano S., Gloux S.,
RA Lelaure V., Mottier S., Galibert F., Aves S.J., Xiang Z., Hunt C.,
RA Moore K., Hurst S.M., Lucas M., Rochet M., Gaillardin C., Tallada V.A.,
RA Garzon A., Thode G., Daga R.R., Cruzado L., Jimenez J., Sanchez M.,
RA del Rey F., Benito J., Dominguez A., Revuelta J.L., Moreno S.,
RA Armstrong J., Forsburg S.L., Cerutti L., Lowe T., McCombie W.R.,
RA Paulsen I., Potashkin J., Shpakovski G.V., Ussery D., Barrell B.G.,
RA Nurse P.;
RT "The genome sequence of Schizosaccharomyces pombe.";
RL Nature 415:871-880(2002).
RN [2] {ECO:0000305}
RP SUBCELLULAR LOCATION [LARGE SCALE ANALYSIS].
RX PubMed=16823372; DOI=10.1038/nbt1222;
RA Matsuyama A., Arai R., Yashiroda Y., Shirai A., Kamata A., Sekido S.,
RA Kobayashi Y., Hashimoto A., Hamamoto M., Hiraoka Y., Horinouchi S.,
RA Yoshida M.;
RT "ORFeome cloning and global analysis of protein localization in the fission
RT yeast Schizosaccharomyces pombe.";
RL Nat. Biotechnol. 24:841-847(2006).
RN [3]
RP PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-301 AND SER-464, AND
RP IDENTIFICATION BY MASS SPECTROMETRY.
RX PubMed=18257517; DOI=10.1021/pr7006335;
RA Wilson-Grady J.T., Villen J., Gygi S.P.;
RT "Phosphoproteome analysis of fission yeast.";
RL J. Proteome Res. 7:1088-1097(2008).
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000269|PubMed:16823372}. Nucleus
CC {ECO:0000269|PubMed:16823372}. Note=Barrier septum. Cell tip.
CC {ECO:0000269|PubMed:16823372}.
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DR EMBL; CU329671; CAA21894.1; -; Genomic_DNA.
DR PIR; T40734; T40734.
DR RefSeq; NP_596483.1; NM_001022403.2.
DR AlphaFoldDB; O94294; -.
DR SMR; O94294; -.
DR BioGRID; 277685; 9.
DR STRING; 4896.SPBC887.09c.1; -.
DR iPTMnet; O94294; -.
DR MaxQB; O94294; -.
DR PaxDb; O94294; -.
DR PRIDE; O94294; -.
DR EnsemblFungi; SPBC887.09c.1; SPBC887.09c.1:pep; SPBC887.09c.
DR GeneID; 2541171; -.
DR KEGG; spo:SPBC887.09c; -.
DR PomBase; SPBC887.09c; sog2.
DR VEuPathDB; FungiDB:SPBC887.09c; -.
DR eggNOG; KOG0619; Eukaryota.
DR HOGENOM; CLU_015898_0_0_1; -.
DR InParanoid; O94294; -.
DR OMA; NDENEWQ; -.
DR PhylomeDB; O94294; -.
DR Reactome; R-SPO-983168; Antigen processing: Ubiquitination & Proteasome degradation.
DR PRO; PR:O94294; -.
DR Proteomes; UP000002485; Chromosome II.
DR GO; GO:0032153; C:cell division site; IDA:PomBase.
DR GO; GO:0051286; C:cell tip; HDA:PomBase.
DR GO; GO:0005737; C:cytoplasm; IDA:PomBase.
DR GO; GO:0005829; C:cytosol; HDA:PomBase.
DR GO; GO:0044732; C:mitotic spindle pole body; IDA:PomBase.
DR GO; GO:0005634; C:nucleus; HDA:PomBase.
DR GO; GO:0035591; F:signaling adaptor activity; EXP:PomBase.
DR GO; GO:0061161; P:positive regulation of establishment of bipolar cell polarity regulating cell shape; IMP:PomBase.
DR GO; GO:0062200; P:RAM/MOR signaling pathway; IMP:PomBase.
DR Gene3D; 3.80.10.10; -; 1.
DR InterPro; IPR001611; Leu-rich_rpt.
DR InterPro; IPR003591; Leu-rich_rpt_typical-subtyp.
DR InterPro; IPR032675; LRR_dom_sf.
DR InterPro; IPR019487; RAM_signalling_pathway_SOG2.
DR Pfam; PF13855; LRR_8; 1.
DR Pfam; PF10428; SOG2; 2.
DR SMART; SM00369; LRR_TYP; 4.
DR PROSITE; PS51450; LRR; 7.
PE 1: Evidence at protein level;
KW Cytoplasm; Leucine-rich repeat; Nucleus; Phosphoprotein;
KW Reference proteome; Repeat.
FT CHAIN 1..886
FT /note="Leucine-rich repeat-containing protein sog2"
FT /id="PRO_0000312230"
FT REPEAT 28..49
FT /note="LRR 1"
FT REPEAT 53..74
FT /note="LRR 2"
FT REPEAT 76..97
FT /note="LRR 3"
FT REPEAT 99..120
FT /note="LRR 4"
FT REPEAT 122..143
FT /note="LRR 5"
FT REPEAT 145..166
FT /note="LRR 6"
FT /evidence="ECO:0000255"
FT REGION 236..288
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 301..364
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 394..431
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 455..483
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 311..364
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 462..476
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT MOD_RES 301
FT /note="Phosphoserine"
FT /evidence="ECO:0000269|PubMed:18257517"
FT MOD_RES 464
FT /note="Phosphoserine"
FT /evidence="ECO:0000269|PubMed:18257517"
SQ SEQUENCE 886 AA; 96993 MW; 7D334E5FFD9271F4 CRC64;
MSAHEVSSTK NSEIERIIKE AEDAGPENAL TLDLSHLNLR ELPYEQLERI QGRIARLALG
HNFIKSIGPE ILKFTRLRYL NIRSNVLREF PESLCRLESL EILDISRNKI KQLPESFGAL
MNLKVLSISK NRLFELPTYI AHMPNLEILK IENNHIVFPP PHIANNDLQD SDMQLFIANI
KGYLSRNESV FRTRSESTVS AALSASANLS HSEENDSSVV DSYLFSAPSD TSHAVSPGML
TFVTPSPHSH SPAGHQQSTP KSTLSKTNEN SEGTLYDSNV AHGCTHPPSL NQLNKFHLDA
SPRQARPRRS VSLATGLNSP SVSKPPSSAT GPLYHSPQSS LTNSSVASAD VQERTHNTNG
ASPIQDQISE FTDQHQNPSN NDAASTQSIL KTAPTQLSAS AKTSAISLPE VAKKERNRSN
STNDDYSSTR LPSSVLHRLE ALKEARKLSE QLPNRIFAQD PHPSPRLKKE ETHENGSNLT
NDSVNSYFSN IGGSEVEMKH SAFEKTLESS RGILFSLSQV QQALRQQLLF CSNPVVLDSM
RHVLHTANVQ IKRLILCFED TQQSNDGTAN INSIVNASLS CISSFRKLIE VTKKFLNELT
SRADVRYVRL LLLILFDAAK ELQNALVPLS PSQPHSGNNI FADQVRQSPT SMIRTASGLT
NRIVSVEKPA SVMNPEIDKQ IQDQVALATN SAMSVLTLLI DAVPKNNQPD LVNENIAPNL
ISKLRELGSL SAAACDVTRK LKHRLLTFQT NPEELEWQLF LDDTQAFVKS IIAVANLAKA
LSSEYTFQKS VLAGLSAATR STKDLTILLS SSARHYTESS LATPVPLMSP IARVPATPLS
AALGSAAQSI TSPLIMSPAA IPASAYSTNK IDYFTDADGN VEGLQR
