ID   SOHB_BUCSC              Reviewed;         305 AA.
AC   Q44600;
DT   01-NOV-1997, integrated into UniProtKB/Swiss-Prot.
DT   01-NOV-1997, sequence version 1.
DT   03-AUG-2022, entry version 79.
DE   RecName: Full=Probable protease SohB;
DE            EC=3.4.21.-;
DE   Flags: Fragment;
GN   Name=sohB;
OS   Buchnera aphidicola subsp. Schlechtendalia chinensis.
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Erwiniaceae; Buchnera.
OX   NCBI_TaxID=118110;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX   PubMed=7742976; DOI=10.1111/j.1365-2583.1995.tb00007.x;
RA   Lai C.-Y., Baumann P., Moran N.A.;
RT   "Genetics of the tryptophan biosynthetic pathway of the prokaryotic
RT   endosymbiont (Buchnera) of the aphid Schlechtendalia chinensis.";
RL   Insect Mol. Biol. 4:47-59(1995).
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000305}; Multi-pass membrane
CC       protein {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the peptidase S49 family. {ECO:0000305}.
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DR   EMBL; U09185; AAA92792.1; -; Genomic_DNA.
DR   AlphaFoldDB; Q44600; -.
DR   SMR; Q44600; -.
DR   STRING; 118110.XW81_01325; -.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0004252; F:serine-type endopeptidase activity; IEA:InterPro.
DR   GO; GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
DR   CDD; cd07023; S49_Sppa_N_C; 1.
DR   InterPro; IPR029045; ClpP/crotonase-like_dom_sf.
DR   InterPro; IPR002142; Peptidase_S49.
DR   InterPro; IPR013703; Peptidase_S49_N_proteobac.
DR   Pfam; PF01343; Peptidase_S49; 1.
DR   Pfam; PF08496; Peptidase_S49_N; 1.
DR   SUPFAM; SSF52096; SSF52096; 1.
PE   3: Inferred from homology;
KW   Cell membrane; Hydrolase; Membrane; Protease; Serine protease;
KW   Transmembrane; Transmembrane helix.
FT   CHAIN           1..>305
FT                   /note="Probable protease SohB"
FT                   /id="PRO_0000171447"
FT   TRANSMEM        9..29
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        185..205
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   ACT_SITE        179
FT                   /note="Nucleophile"
FT                   /evidence="ECO:0000250"
FT   ACT_SITE        231
FT                   /note="Proton donor/acceptor"
FT                   /evidence="ECO:0000250"
FT   NON_TER         305
SQ   SEQUENCE   305 AA;  34840 MW;  4A29A59D14F00918 CRC64;
     MDFILNYALF FFKIFTLFAL ILTIFLIIVN VARHKSKKKY ELDIVSLNSY YEHVKNKIIL
     STMSTYEKKI WNKSNKLFKK TRSKINMTFL KKNKYYLNQN NPILYVLDFK GNVSASEVTS
     LREEISAIIL AAKENDEVLL RLESGGGVIH GYGLASSQLS RLREKNIRLT VSVDKIAASG
     GYMMACVANY IIAAPFSVIG SIGVVAQIPN FNKLLKKNNV DMELHTSGLY KRTLTVFGEN
     TKEAREKFCK DLNFTHVLFK EFVHSMRPSL NIDEVSTGEH WFGTTALEKK LIDKIETSDD
     FIISR