ID   SOLI_RALSL              Reviewed;         204 AA.
AC   O30920;
DT   01-DEC-2000, integrated into UniProtKB/Swiss-Prot.
DT   01-JAN-1998, sequence version 1.
DT   25-MAY-2022, entry version 74.
DE   RecName: Full=Acyl-homoserine-lactone synthase;
DE            EC=2.3.1.184;
DE   AltName: Full=Autoinducer synthesis protein SolI;
GN   Name=solI;
OS   Ralstonia solanacearum (Pseudomonas solanacearum).
OC   Bacteria; Proteobacteria; Betaproteobacteria; Burkholderiales;
OC   Burkholderiaceae; Ralstonia.
OX   NCBI_TaxID=305;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=AW1;
RX   PubMed=9371457; DOI=10.1128/jb.179.22.7089-7097.1997;
RA   Flavier A.B., Ganova-Raeva L.M., Schell M.A., Denny T.P.;
RT   "Hierarchical autoinduction in Ralstonia solanacearum: control of acyl-
RT   homoserine lactone production by a novel autoregulatory system responsive
RT   to 3-hydroxypalmitic acid methyl ester.";
RL   J. Bacteriol. 179:7089-7097(1997).
CC   -!- FUNCTION: Required for the synthesis of acyl-HSL autoinducers that bind
CC       to SolR.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=a fatty acyl-[ACP] + S-adenosyl-L-methionine = an N-acyl-L-
CC         homoserine lactone + H(+) + holo-[ACP] + S-methyl-5'-thioadenosine;
CC         Xref=Rhea:RHEA:10096, Rhea:RHEA-COMP:9685, Rhea:RHEA-COMP:14125,
CC         ChEBI:CHEBI:15378, ChEBI:CHEBI:17509, ChEBI:CHEBI:55474,
CC         ChEBI:CHEBI:59789, ChEBI:CHEBI:64479, ChEBI:CHEBI:138651;
CC         EC=2.3.1.184;
CC   -!- SIMILARITY: Belongs to the autoinducer synthase family.
CC       {ECO:0000255|PROSITE-ProRule:PRU00533}.
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DR   EMBL; AF021840; AAC45948.1; -; Genomic_DNA.
DR   AlphaFoldDB; O30920; -.
DR   SMR; O30920; -.
DR   GO; GO:0061579; F:N-acyl homoserine lactone synthase activity; IEA:UniProtKB-EC.
DR   GO; GO:0009372; P:quorum sensing; IEA:UniProtKB-KW.
DR   InterPro; IPR016181; Acyl_CoA_acyltransferase.
DR   InterPro; IPR018311; Autoind_synth_CS.
DR   InterPro; IPR001690; Autoind_synthase.
DR   PANTHER; PTHR39322; PTHR39322; 1.
DR   Pfam; PF00765; Autoind_synth; 1.
DR   PRINTS; PR01549; AUTOINDCRSYN.
DR   SUPFAM; SSF55729; SSF55729; 1.
DR   PROSITE; PS00949; AUTOINDUCER_SYNTH_1; 1.
DR   PROSITE; PS51187; AUTOINDUCER_SYNTH_2; 1.
PE   3: Inferred from homology;
KW   Autoinducer synthesis; Quorum sensing; S-adenosyl-L-methionine;
KW   Transferase.
FT   CHAIN           1..204
FT                   /note="Acyl-homoserine-lactone synthase"
FT                   /id="PRO_0000210896"
SQ   SEQUENCE   204 AA;  22107 MW;  30B348EB2DE9CBDE CRC64;
     MRTFVHGGGR LPEGIDAALA HYRHQVFVGR LGWQLPMADG TFERDQYDRD DTVYVVARDE
     GGTICGCARL LPTTRPYLLK DVFASLLMHG MPPPESPEVW ELSRFAARSG APCPRSGRAD
     WAVRPMLASV VQCAAQRGAR RLIGATFVSM VRLFRRIGVR AHRAGPVRCI GGRPVVACWI
     DIDASTCAAL GIPSASAAPG PVLQ