ID   SOLI_RALSO              Reviewed;         204 AA.
AC   P58584;
DT   23-JAN-2002, integrated into UniProtKB/Swiss-Prot.
DT   23-JAN-2002, sequence version 1.
DT   25-MAY-2022, entry version 104.
DE   RecName: Full=Acyl-homoserine-lactone synthase;
DE            EC=2.3.1.184;
DE   AltName: Full=Autoinducer synthesis protein SolI;
GN   Name=solI; OrderedLocusNames=RSc3286; ORFNames=RS02515;
OS   Ralstonia solanacearum (strain GMI1000) (Pseudomonas solanacearum).
OC   Bacteria; Proteobacteria; Betaproteobacteria; Burkholderiales;
OC   Burkholderiaceae; Ralstonia.
OX   NCBI_TaxID=267608;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=GMI1000;
RX   PubMed=11823852; DOI=10.1038/415497a;
RA   Salanoubat M., Genin S., Artiguenave F., Gouzy J., Mangenot S., Arlat M.,
RA   Billault A., Brottier P., Camus J.-C., Cattolico L., Chandler M.,
RA   Choisne N., Claudel-Renard C., Cunnac S., Demange N., Gaspin C., Lavie M.,
RA   Moisan A., Robert C., Saurin W., Schiex T., Siguier P., Thebault P.,
RA   Whalen M., Wincker P., Levy M., Weissenbach J., Boucher C.A.;
RT   "Genome sequence of the plant pathogen Ralstonia solanacearum.";
RL   Nature 415:497-502(2002).
CC   -!- FUNCTION: Required for the synthesis of acyl-HSL autoinducers that bind
CC       to SolR. {ECO:0000250}.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=a fatty acyl-[ACP] + S-adenosyl-L-methionine = an N-acyl-L-
CC         homoserine lactone + H(+) + holo-[ACP] + S-methyl-5'-thioadenosine;
CC         Xref=Rhea:RHEA:10096, Rhea:RHEA-COMP:9685, Rhea:RHEA-COMP:14125,
CC         ChEBI:CHEBI:15378, ChEBI:CHEBI:17509, ChEBI:CHEBI:55474,
CC         ChEBI:CHEBI:59789, ChEBI:CHEBI:64479, ChEBI:CHEBI:138651;
CC         EC=2.3.1.184;
CC   -!- SIMILARITY: Belongs to the autoinducer synthase family.
CC       {ECO:0000255|PROSITE-ProRule:PRU00533}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; AL646052; CAD17074.1; -; Genomic_DNA.
DR   RefSeq; WP_011003171.1; NC_003295.1.
DR   AlphaFoldDB; P58584; -.
DR   SMR; P58584; -.
DR   STRING; 267608.RSc3286; -.
DR   EnsemblBacteria; CAD17074; CAD17074; RSc3286.
DR   GeneID; 60502798; -.
DR   KEGG; rso:RSc3286; -.
DR   PATRIC; fig|267608.8.peg.3335; -.
DR   eggNOG; COG3916; Bacteria.
DR   HOGENOM; CLU_085711_2_0_4; -.
DR   OMA; GPGNAEW; -.
DR   Proteomes; UP000001436; Chromosome.
DR   GO; GO:0061579; F:N-acyl homoserine lactone synthase activity; IEA:UniProtKB-EC.
DR   GO; GO:0009372; P:quorum sensing; IEA:UniProtKB-KW.
DR   InterPro; IPR016181; Acyl_CoA_acyltransferase.
DR   InterPro; IPR018311; Autoind_synth_CS.
DR   InterPro; IPR001690; Autoind_synthase.
DR   PANTHER; PTHR39322; PTHR39322; 1.
DR   Pfam; PF00765; Autoind_synth; 1.
DR   PRINTS; PR01549; AUTOINDCRSYN.
DR   SUPFAM; SSF55729; SSF55729; 1.
DR   PROSITE; PS00949; AUTOINDUCER_SYNTH_1; 1.
DR   PROSITE; PS51187; AUTOINDUCER_SYNTH_2; 1.
PE   3: Inferred from homology;
KW   Autoinducer synthesis; Quorum sensing; Reference proteome;
KW   S-adenosyl-L-methionine; Transferase.
FT   CHAIN           1..204
FT                   /note="Acyl-homoserine-lactone synthase"
FT                   /id="PRO_0000210895"
SQ   SEQUENCE   204 AA;  22037 MW;  EDD58E874F165BE4 CRC64;
     MQTFIHGGGR LPEAVDAALA HYRHQIFVGQ LGWQLPMADG RFERDQYDRD DTVYVVARDA
     DGAICGCARL LPTTRPYLLK DVFAPLLMRG VPAPESPGVW ELSRFAARSG ASRARGARPD
     WAVRPMLASV VQCAAQRGAR RLIGVTFVSM VRLFRRIGVR AHHAGPVRCI GGRPVVACWI
     DIDASTCAAL GIPGASVVPG PALQ