SOLR_CLOAB
ID SOLR_CLOAB Reviewed; 318 AA.
AC P33746;
DT 01-FEB-1994, integrated into UniProtKB/Swiss-Prot.
DT 01-FEB-1994, sequence version 1.
DT 25-MAY-2022, entry version 120.
DE RecName: Full=Sol locus transcriptional repressor;
GN Name=solR; OrderedLocusNames=CA_P0161;
OS Clostridium acetobutylicum (strain ATCC 824 / DSM 792 / JCM 1419 / LMG 5710
OS / VKM B-1787).
OG Plasmid pSOL1.
OC Bacteria; Firmicutes; Clostridia; Eubacteriales; Clostridiaceae;
OC Clostridium.
OX NCBI_TaxID=272562;
RN [1]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC STRAIN=ATCC 824 / DSM 792 / JCM 1419 / LMG 5710 / VKM B-1787;
RX PubMed=8226639; DOI=10.1128/jb.175.21.6959-6969.1993;
RA Fischer R.J., Helms J., Duerre P.;
RT "Cloning, sequencing, and molecular analysis of the sol operon of
RT Clostridium acetobutylicum, a chromosomal locus involved in
RT solventogenesis.";
RL J. Bacteriol. 175:6959-6969(1993).
RN [2]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC STRAIN=ATCC 824 / DSM 792 / JCM 1419 / LMG 5710 / VKM B-1787;
RX PubMed=9864345; DOI=10.1128/jb.181.1.319-330.1999;
RA Nair R.V., Green E.M., Watson D.E., Bennett G.N., Papoutsakis E.T.;
RT "Regulation of the sol locus genes for butanol and acetone formation in
RT Clostridium acetobutylicum ATCC 824 by a putative transcriptional
RT repressor.";
RL J. Bacteriol. 181:319-330(1999).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 824 / DSM 792 / JCM 1419 / LMG 5710 / VKM B-1787;
RX PubMed=11466286; DOI=10.1128/jb.183.16.4823-4838.2001;
RA Noelling J., Breton G., Omelchenko M.V., Makarova K.S., Zeng Q., Gibson R.,
RA Lee H.M., Dubois J., Qiu D., Hitti J., Wolf Y.I., Tatusov R.L., Sabathe F.,
RA Doucette-Stamm L.A., Soucaille P., Daly M.J., Bennett G.N., Koonin E.V.,
RA Smith D.R.;
RT "Genome sequence and comparative analysis of the solvent-producing
RT bacterium Clostridium acetobutylicum.";
RL J. Bacteriol. 183:4823-4838(2001).
CC -!- FUNCTION: Transcriptional repressor of the sol locus (adhE/aad, ctfA,
CC ctfB and adc) genes for butanol and acetone formation.
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DR EMBL; X72831; CAA51342.1; -; Genomic_DNA.
DR EMBL; L14817; AAD04637.1; -; Genomic_DNA.
DR EMBL; AE001438; AAK76906.1; -; Genomic_DNA.
DR PIR; B36972; B36972.
DR PIR; S33433; S33433.
DR RefSeq; NP_149324.1; NC_001988.2.
DR RefSeq; WP_010890845.1; NC_001988.2.
DR AlphaFoldDB; P33746; -.
DR SMR; P33746; -.
DR EnsemblBacteria; AAK76906; AAK76906; CA_P0161.
DR GeneID; 45000386; -.
DR KEGG; cac:CA_P0161; -.
DR PATRIC; fig|272562.8.peg.161; -.
DR HOGENOM; CLU_873457_0_0_9; -.
DR OMA; ACYDRAV; -.
DR OrthoDB; 1382732at2; -.
DR Proteomes; UP000000814; Plasmid pSOL1.
DR Gene3D; 1.25.40.10; -; 1.
DR InterPro; IPR011990; TPR-like_helical_dom_sf.
DR InterPro; IPR019734; TPR_repeat.
DR Pfam; PF13181; TPR_8; 2.
DR SMART; SM00028; TPR; 5.
DR PROSITE; PS50005; TPR; 5.
DR PROSITE; PS50293; TPR_REGION; 1.
PE 4: Predicted;
KW Plasmid; Reference proteome; Repeat; Repressor; TPR repeat; Transcription;
KW Transcription regulation.
FT CHAIN 1..318
FT /note="Sol locus transcriptional repressor"
FT /id="PRO_0000106446"
FT REPEAT 65..98
FT /note="TPR 1"
FT REPEAT 99..132
FT /note="TPR 2"
FT REPEAT 133..166
FT /note="TPR 3"
FT REPEAT 167..199
FT /note="TPR 4"
SQ SEQUENCE 318 AA; 36940 MW; 49CED287FEE4EFE8 CRC64;
MNLLNLFTYV IPIAICIILP IFIIVTHFQI KSLNKAVTSF NKGDRSNALE ILSKLVKSPI
KNVKANAYIT RERIYFYSRD FELSLRDLLQ AIKLRPKTIN DVYSFALSYH ILGEPERALK
YFLRAVELQP NVGISYENLA WFYYLTGKYD KAIENFEKAI SMGSTNSVYR SLGITYAKIG
DYKKSEEYLK KALDAEPEKP STHIYFSYLK RKTNDIKLAK EYALKAIELN KNNFDGYKNL
AEVNLAEDDY DGFYKNLEIF LEKINFVTNG EDFNDEVYDK VKDNEKFKEL IAKTKVIKFK
DLGIEIDDKK ILNGKFLV