ID   SOML_ACITR              Reviewed;         232 AA.
AC   O93262;
DT   16-NOV-2001, integrated into UniProtKB/Swiss-Prot.
DT   01-NOV-1998, sequence version 1.
DT   25-MAY-2022, entry version 68.
DE   RecName: Full=Somatolactin;
DE            Short=SL;
DE   Flags: Precursor;
OS   Acipenser transmontanus (White sturgeon).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Chondrostei; Acipenseriformes; Acipenseridae; Acipenser.
OX   NCBI_TaxID=7904;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [MRNA].
RC   TISSUE=Pituitary;
RX   PubMed=10208767; DOI=10.1006/gcen.1998.7250;
RA   Amemiya Y., Sogabe Y., Nozaki M., Takahashi A., Kawauchi H.;
RT   "Somatolactin in the white sturgeon and African lungfish and its
RT   evolutionary significance.";
RL   Gen. Comp. Endocrinol. 114:181-190(1999).
CC   -!- SUBCELLULAR LOCATION: Secreted.
CC   -!- SIMILARITY: Belongs to the somatotropin/prolactin family.
CC       {ECO:0000305}.
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DR   EMBL; AB017200; BAA32608.1; -; mRNA.
DR   AlphaFoldDB; O93262; -.
DR   SMR; O93262; -.
DR   GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR   GO; GO:0005179; F:hormone activity; IEA:UniProtKB-KW.
DR   Gene3D; 1.20.1250.10; -; 1.
DR   InterPro; IPR009079; 4_helix_cytokine-like_core.
DR   InterPro; IPR034976; Somatolactin.
DR   InterPro; IPR001400; Somatotropin/Prolactin.
DR   InterPro; IPR018116; Somatotropin_CS.
DR   PANTHER; PTHR11417; PTHR11417; 1.
DR   PANTHER; PTHR11417:SF3; PTHR11417:SF3; 1.
DR   Pfam; PF00103; Hormone_1; 1.
DR   PRINTS; PR00836; SOMATOTROPIN.
DR   SUPFAM; SSF47266; SSF47266; 1.
DR   PROSITE; PS00266; SOMATOTROPIN_1; 1.
DR   PROSITE; PS00338; SOMATOTROPIN_2; 1.
PE   2: Evidence at transcript level;
KW   Disulfide bond; Glycoprotein; Hormone; Secreted; Signal.
FT   SIGNAL          1..24
FT                   /evidence="ECO:0000255"
FT   CHAIN           25..232
FT                   /note="Somatolactin"
FT                   /id="PRO_0000033064"
FT   CARBOHYD        145
FT                   /note="N-linked (GlcNAc...) asparagine"
FT                   /evidence="ECO:0000255"
FT   DISULFID        29..39
FT                   /evidence="ECO:0000250"
FT   DISULFID        89..204
FT                   /evidence="ECO:0000250"
FT   DISULFID        221..229
FT                   /evidence="ECO:0000250"
SQ   SEQUENCE   232 AA;  26908 MW;  97C5C167161B07EC CRC64;
     MQKVKVLQVC AWVLLLWRCW GVLGYPLDCK DEQGSIISCT SISLEKLLDR VIQHAELIYH
     VSEESCTLFE EMFVPVSMRT QQNRARNTCI TKAFPIPGSK SEIQKISDKW LLHSVLMLVQ
     SWIEPLVYLQ KTLDRYDDAP DTILNKTKWV TNKLSSLEQG IVELIRKMLD EGLLAVDHQQ
     TLTRFDVQPE VVESILRDYA VLTCFKKDAH KMEVFLKLLK CRHTDKMSCY IS