ID   SOML_CARAU              Reviewed;         230 AA.
AC   P79697;
DT   01-NOV-1997, integrated into UniProtKB/Swiss-Prot.
DT   01-MAY-1997, sequence version 1.
DT   25-MAY-2022, entry version 70.
DE   RecName: Full=Somatolactin;
DE            Short=SL;
DE   Flags: Precursor;
OS   Carassius auratus (Goldfish).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes;
OC   Cyprinidae; Cyprininae; Carassius.
OX   NCBI_TaxID=7957;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [MRNA].
RX   PubMed=9125164; DOI=10.1006/bbrc.1997.6271;
RA   Cheng K.W., Chan Y.H., Chen Y.D., Yu K.L., Chan K.M.;
RT   "Sequence of a cDNA clone encoding a novel somatolactin in goldfish,
RT   Carassius auratus.";
RL   Biochem. Biophys. Res. Commun. 232:282-287(1997).
CC   -!- SUBCELLULAR LOCATION: Secreted.
CC   -!- SIMILARITY: Belongs to the somatotropin/prolactin family.
CC       {ECO:0000305}.
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DR   EMBL; U72940; AAC60098.1; -; mRNA.
DR   PIR; JC5418; JC5418.
DR   AlphaFoldDB; P79697; -.
DR   SMR; P79697; -.
DR   Ensembl; ENSCART00000093217; ENSCARP00000085318; ENSCARG00000041197.
DR   Proteomes; UP000515129; Genome assembly.
DR   GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR   GO; GO:0005179; F:hormone activity; IEA:UniProtKB-KW.
DR   Gene3D; 1.20.1250.10; -; 1.
DR   InterPro; IPR009079; 4_helix_cytokine-like_core.
DR   InterPro; IPR034976; Somatolactin.
DR   InterPro; IPR001400; Somatotropin/Prolactin.
DR   InterPro; IPR018116; Somatotropin_CS.
DR   PANTHER; PTHR11417; PTHR11417; 1.
DR   PANTHER; PTHR11417:SF3; PTHR11417:SF3; 1.
DR   Pfam; PF00103; Hormone_1; 1.
DR   PRINTS; PR00836; SOMATOTROPIN.
DR   SUPFAM; SSF47266; SSF47266; 1.
DR   PROSITE; PS00338; SOMATOTROPIN_2; 1.
PE   2: Evidence at transcript level;
KW   Disulfide bond; Glycoprotein; Hormone; Reference proteome; Secreted;
KW   Signal.
FT   SIGNAL          1..23
FT                   /evidence="ECO:0000255"
FT   CHAIN           24..230
FT                   /note="Somatolactin"
FT                   /id="PRO_0000033066"
FT   CARBOHYD        226
FT                   /note="N-linked (GlcNAc...) asparagine"
FT                   /evidence="ECO:0000255"
FT   DISULFID        28..38
FT                   /evidence="ECO:0000250"
FT   DISULFID        87..202
FT                   /evidence="ECO:0000250"
FT   DISULFID        219..227
FT                   /evidence="ECO:0000250"
SQ   SEQUENCE   230 AA;  25735 MW;  CBC5DB347C6116DC CRC64;
     MKKTTVLQVC MVFVVCSLQA VIGSPVDCPD QDTAGVSCII SLEKLLERAV QHAELIHHIA
     EESKLLFDEM LISFGVVNLH ISEGTMCSPK TVSVPMSKTE IQQISDKWLL HSVLILVQFW
     INPLVDVQAS LMNYQNAPSA LVDRSKLMST KITSLEQGIL VLIRQILGEG GLVVEGPEDT
     SDHFVSSDTF ETVRRDYSVI YCFRKDAHKI QTLLKLLKCR QIDKENCSLF