ID   SOML_SCIOC              Reviewed;         231 AA.
AC   Q9YGK7;
DT   16-NOV-2001, integrated into UniProtKB/Swiss-Prot.
DT   01-MAY-1999, sequence version 1.
DT   25-MAY-2022, entry version 66.
DE   RecName: Full=Somatolactin;
DE            Short=SL;
DE   Flags: Precursor;
OS   Sciaenops ocellatus (Red drum) (Perca ocellata).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC   Eupercaria; Sciaenidae; Sciaenops.
OX   NCBI_TaxID=76340;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [MRNA].
RC   TISSUE=Pituitary;
RX   PubMed=9882545; DOI=10.1006/gcen.1998.7180;
RA   Zhu Y., Yoshiura Y., Kikuchi K., Aida K., Thomas P.;
RT   "Cloning and phylogenetic relationship of red drum somatolactin cDNA and
RT   effects of light on pituitary somatolactin mRNA expression.";
RL   Gen. Comp. Endocrinol. 113:69-79(1999).
CC   -!- SUBCELLULAR LOCATION: Secreted.
CC   -!- TISSUE SPECIFICITY: Pituitary gland.
CC   -!- SIMILARITY: Belongs to the somatotropin/prolactin family.
CC       {ECO:0000305}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; AF062520; AAD17534.1; -; mRNA.
DR   AlphaFoldDB; Q9YGK7; -.
DR   SMR; Q9YGK7; -.
DR   GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR   GO; GO:0005179; F:hormone activity; IEA:UniProtKB-KW.
DR   Gene3D; 1.20.1250.10; -; 1.
DR   InterPro; IPR009079; 4_helix_cytokine-like_core.
DR   InterPro; IPR034976; Somatolactin.
DR   InterPro; IPR001400; Somatotropin/Prolactin.
DR   InterPro; IPR018116; Somatotropin_CS.
DR   PANTHER; PTHR11417; PTHR11417; 1.
DR   PANTHER; PTHR11417:SF3; PTHR11417:SF3; 1.
DR   Pfam; PF00103; Hormone_1; 1.
DR   PRINTS; PR00836; SOMATOTROPIN.
DR   SUPFAM; SSF47266; SSF47266; 1.
DR   PROSITE; PS00266; SOMATOTROPIN_1; 1.
DR   PROSITE; PS00338; SOMATOTROPIN_2; 1.
PE   2: Evidence at transcript level;
KW   Disulfide bond; Glycoprotein; Hormone; Secreted; Signal.
FT   SIGNAL          1..24
FT                   /evidence="ECO:0000255"
FT   CHAIN           25..231
FT                   /note="Somatolactin"
FT                   /id="PRO_0000033074"
FT   CARBOHYD        145
FT                   /note="N-linked (GlcNAc...) asparagine"
FT                   /evidence="ECO:0000255"
FT   DISULFID        29..39
FT                   /evidence="ECO:0000250"
FT   DISULFID        89..205
FT                   /evidence="ECO:0000250"
FT   DISULFID        222..230
FT                   /evidence="ECO:0000250"
SQ   SEQUENCE   231 AA;  26658 MW;  4FB039DEE6EDBD01 CRC64;
     MYMMTALQRG VWASLLWPYL ITISIPLDCK EEQGSLSRCP SISQEKLLDR VIQHAELIYR
     VSEESCSLFE EMFVPFSLQL QRNQAGYACI TKAFPIPSSK SEIQQISDKW LLHSVLMLVQ
     SWIGPLAYLQ NTMDHYDGAP DMLLNKTKWV SEKLISLEQG VVVLIKKMLD EGILTTTYSE
     QGLFQYEVQP DMLESVMKDY NLLSCFKKDA HKMEILLKLL KCRQTDIYNC P