ID   SOP4_ASHGO              Reviewed;         231 AA.
AC   Q752F7;
DT   18-MAR-2008, integrated into UniProtKB/Swiss-Prot.
DT   18-MAR-2008, sequence version 2.
DT   25-MAY-2022, entry version 70.
DE   RecName: Full=Protein SOP4;
DE   Flags: Precursor;
GN   Name=SOP4; OrderedLocusNames=AFR619W;
OS   Ashbya gossypii (strain ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056)
OS   (Yeast) (Eremothecium gossypii).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC   Saccharomycetales; Saccharomycetaceae; Eremothecium.
OX   NCBI_TaxID=284811;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056;
RX   PubMed=15001715; DOI=10.1126/science.1095781;
RA   Dietrich F.S., Voegeli S., Brachat S., Lerch A., Gates K., Steiner S.,
RA   Mohr C., Poehlmann R., Luedi P., Choi S., Wing R.A., Flavier A.,
RA   Gaffney T.D., Philippsen P.;
RT   "The Ashbya gossypii genome as a tool for mapping the ancient Saccharomyces
RT   cerevisiae genome.";
RL   Science 304:304-307(2004).
RN   [2]
RP   GENOME REANNOTATION.
RC   STRAIN=ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056;
RX   PubMed=23749448; DOI=10.1534/g3.112.002881;
RA   Dietrich F.S., Voegeli S., Kuo S., Philippsen P.;
RT   "Genomes of Ashbya fungi isolated from insects reveal four mating-type
RT   loci, numerous translocations, lack of transposons, and distinct gene
RT   duplications.";
RL   G3 (Bethesda) 3:1225-1239(2013).
CC   -!- FUNCTION: Involved in the export of PMA1, possibly through the
CC       monitoring or assisting of PMA1 folding and acquisition of competence
CC       to enter vesicles. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Endoplasmic reticulum membrane {ECO:0000250};
CC       Single-pass type I membrane protein {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the SOP4 family. {ECO:0000305}.
CC   -!- SEQUENCE CAUTION:
CC       Sequence=AAS53990.1; Type=Erroneous initiation; Evidence={ECO:0000305};
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DR   EMBL; AE016819; AAS53990.1; ALT_INIT; Genomic_DNA.
DR   RefSeq; NP_986166.1; NM_212302.1.
DR   AlphaFoldDB; Q752F7; -.
DR   SMR; Q752F7; -.
DR   STRING; 33169.AAS53990; -.
DR   PRIDE; Q752F7; -.
DR   GeneID; 4622453; -.
DR   KEGG; ago:AGOS_AFR619W; -.
DR   eggNOG; ENOG502RXGD; Eukaryota.
DR   InParanoid; Q752F7; -.
DR   Proteomes; UP000000591; Chromosome VI.
DR   GO; GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0015031; P:protein transport; IEA:UniProtKB-KW.
DR   InterPro; IPR031395; Sop4.
DR   Pfam; PF17081; SOP4; 1.
PE   3: Inferred from homology;
KW   Endoplasmic reticulum; Glycoprotein; Membrane; Protein transport;
KW   Reference proteome; Signal; Transmembrane; Transmembrane helix; Transport.
FT   SIGNAL          1..16
FT                   /evidence="ECO:0000255"
FT   CHAIN           17..231
FT                   /note="Protein SOP4"
FT                   /id="PRO_0000324495"
FT   TOPO_DOM        17..183
FT                   /note="Lumenal"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        184..200
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        201..231
FT                   /note="Cytoplasmic"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        48
FT                   /note="N-linked (GlcNAc...) asparagine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        79
FT                   /note="N-linked (GlcNAc...) asparagine"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   231 AA;  26068 MW;  E54CB2BC80668C48 CRC64;
     MRALLLAFQL LSVVAALTTV NCRLDLSPRQ ISRKDLLRTH LRLYQVGNFS GQPYSAKATL
     RDPEGRFRFE DLPVSHDENS TVYFQLVASS QDYNLKPNRV LIEVQGRGEG KEPTVRAFQN
     VFGREHFPSP EILYPEQLVE LEAEPELVIS YVHAAPMRNY IVSRRSGILD SGPLAGIFRS
     KYKMAAVVTI IALLLFPMLV EKFDPATVEA IKEQRLSQTR EKYAAVGESN S