ID   SOP4_CANGA              Reviewed;         244 AA.
AC   Q6FNE2;
DT   18-MAR-2008, integrated into UniProtKB/Swiss-Prot.
DT   19-JUL-2004, sequence version 1.
DT   25-MAY-2022, entry version 70.
DE   RecName: Full=Protein SOP4;
DE   Flags: Precursor;
GN   Name=SOP4; OrderedLocusNames=CAGL0K00649g;
OS   Candida glabrata (strain ATCC 2001 / CBS 138 / JCM 3761 / NBRC 0622 / NRRL
OS   Y-65) (Yeast) (Torulopsis glabrata).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC   Saccharomycetales; Saccharomycetaceae; Nakaseomyces;
OC   Nakaseomyces/Candida clade.
OX   NCBI_TaxID=284593;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 2001 / CBS 138 / JCM 3761 / NBRC 0622 / NRRL Y-65;
RX   PubMed=15229592; DOI=10.1038/nature02579;
RA   Dujon B., Sherman D., Fischer G., Durrens P., Casaregola S., Lafontaine I.,
RA   de Montigny J., Marck C., Neuveglise C., Talla E., Goffard N., Frangeul L.,
RA   Aigle M., Anthouard V., Babour A., Barbe V., Barnay S., Blanchin S.,
RA   Beckerich J.-M., Beyne E., Bleykasten C., Boisrame A., Boyer J.,
RA   Cattolico L., Confanioleri F., de Daruvar A., Despons L., Fabre E.,
RA   Fairhead C., Ferry-Dumazet H., Groppi A., Hantraye F., Hennequin C.,
RA   Jauniaux N., Joyet P., Kachouri R., Kerrest A., Koszul R., Lemaire M.,
RA   Lesur I., Ma L., Muller H., Nicaud J.-M., Nikolski M., Oztas S.,
RA   Ozier-Kalogeropoulos O., Pellenz S., Potier S., Richard G.-F.,
RA   Straub M.-L., Suleau A., Swennen D., Tekaia F., Wesolowski-Louvel M.,
RA   Westhof E., Wirth B., Zeniou-Meyer M., Zivanovic Y., Bolotin-Fukuhara M.,
RA   Thierry A., Bouchier C., Caudron B., Scarpelli C., Gaillardin C.,
RA   Weissenbach J., Wincker P., Souciet J.-L.;
RT   "Genome evolution in yeasts.";
RL   Nature 430:35-44(2004).
CC   -!- FUNCTION: Involved in the export of PMA1, possibly through the
CC       monitoring or assisting of PMA1 folding and acquisition of competence
CC       to enter vesicles. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Endoplasmic reticulum membrane {ECO:0000250};
CC       Single-pass type I membrane protein {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the SOP4 family. {ECO:0000305}.
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DR   EMBL; CR380957; CAG61213.1; -; Genomic_DNA.
DR   RefSeq; XP_448252.1; XM_448252.1.
DR   AlphaFoldDB; Q6FNE2; -.
DR   SMR; Q6FNE2; -.
DR   STRING; 5478.XP_448252.1; -.
DR   EnsemblFungi; CAG61213; CAG61213; CAGL0K00649g.
DR   GeneID; 2890228; -.
DR   KEGG; cgr:CAGL0K00649g; -.
DR   CGD; CAL0134137; CAGL0K00649g.
DR   VEuPathDB; FungiDB:CAGL0K00649g; -.
DR   eggNOG; ENOG502RXGD; Eukaryota.
DR   HOGENOM; CLU_102669_0_0_1; -.
DR   InParanoid; Q6FNE2; -.
DR   OMA; PYITVEL; -.
DR   Proteomes; UP000002428; Chromosome K.
DR   GO; GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0006888; P:endoplasmic reticulum to Golgi vesicle-mediated transport; IEA:EnsemblFungi.
DR   GO; GO:0015031; P:protein transport; IEA:UniProtKB-KW.
DR   InterPro; IPR031395; Sop4.
DR   Pfam; PF17081; SOP4; 1.
PE   3: Inferred from homology;
KW   Endoplasmic reticulum; Glycoprotein; Membrane; Protein transport;
KW   Reference proteome; Signal; Transmembrane; Transmembrane helix; Transport.
FT   SIGNAL          1..18
FT                   /evidence="ECO:0000255"
FT   CHAIN           19..244
FT                   /note="Protein SOP4"
FT                   /id="PRO_0000324496"
FT   TOPO_DOM        19..199
FT                   /note="Lumenal"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        200..216
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        217..244
FT                   /note="Cytoplasmic"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        59
FT                   /note="N-linked (GlcNAc...) asparagine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        76
FT                   /note="N-linked (GlcNAc...) asparagine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        91
FT                   /note="N-linked (GlcNAc...) asparagine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        121
FT                   /note="N-linked (GlcNAc...) asparagine"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   244 AA;  28466 MW;  938BE5352B8E3DA1 CRC64;
     MWKSVIYLFV LLLGVIRAED VKDLRNNEVS IKGRLELSEI DISAYMIPRC SFRLYQIGNY
     SADKPFHQIT RIKDKNGTFE FNHVPINHGV NESTYFVMTP SSRDFNLLPQ RVLVEVTNIF
     NETTGKVEQQ LKAFRNYFGR EYFPSKDIHF PDKLEEMDAL PYISIKMSKM LPFRDYLQQR
     NVGLLQSGPL AGILNSKWKI AAVITLLALM TFPYLVEKLD PETARAMKEE ARKKQREKYV
     VKEE