ID   SOP4_VANPO              Reviewed;         230 AA.
AC   A7TFH0;
DT   18-MAR-2008, integrated into UniProtKB/Swiss-Prot.
DT   02-OCT-2007, sequence version 1.
DT   25-MAY-2022, entry version 49.
DE   RecName: Full=Protein SOP4;
DE   Flags: Precursor;
GN   Name=SOP4; ORFNames=Kpol_2002p55;
OS   Vanderwaltozyma polyspora (strain ATCC 22028 / DSM 70294 / BCRC 21397 / CBS
OS   2163 / NBRC 10782 / NRRL Y-8283 / UCD 57-17) (Kluyveromyces polysporus).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC   Saccharomycetales; Saccharomycetaceae; Vanderwaltozyma.
OX   NCBI_TaxID=436907;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 22028 / DSM 70294 / BCRC 21397 / CBS 2163 / NBRC 10782 / NRRL
RC   Y-8283 / UCD 57-17;
RX   PubMed=17494770; DOI=10.1073/pnas.0608218104;
RA   Scannell D.R., Frank A.C., Conant G.C., Byrne K.P., Woolfit M., Wolfe K.H.;
RT   "Independent sorting-out of thousands of duplicated gene pairs in two yeast
RT   species descended from a whole-genome duplication.";
RL   Proc. Natl. Acad. Sci. U.S.A. 104:8397-8402(2007).
CC   -!- FUNCTION: Involved in the export of PMA1, possibly through the
CC       monitoring or assisting of PMA1 folding and acquisition of competence
CC       to enter vesicles. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Endoplasmic reticulum membrane {ECO:0000250};
CC       Single-pass type I membrane protein {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the SOP4 family. {ECO:0000305}.
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DR   EMBL; DS480383; EDO18984.1; -; Genomic_DNA.
DR   RefSeq; XP_001646842.1; XM_001646792.1.
DR   AlphaFoldDB; A7TFH0; -.
DR   SMR; A7TFH0; -.
DR   STRING; 436907.A7TFH0; -.
DR   EnsemblFungi; EDO18984; EDO18984; Kpol_2002p55.
DR   GeneID; 5547310; -.
DR   KEGG; vpo:Kpol_2002p55; -.
DR   eggNOG; ENOG502RXGD; Eukaryota.
DR   HOGENOM; CLU_102669_0_0_1; -.
DR   InParanoid; A7TFH0; -.
DR   OMA; PYITVEL; -.
DR   OrthoDB; 1591902at2759; -.
DR   PhylomeDB; A7TFH0; -.
DR   Proteomes; UP000000267; Unassembled WGS sequence.
DR   GO; GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0015031; P:protein transport; IEA:UniProtKB-KW.
DR   InterPro; IPR031395; Sop4.
DR   Pfam; PF17081; SOP4; 1.
PE   3: Inferred from homology;
KW   Endoplasmic reticulum; Glycoprotein; Membrane; Protein transport;
KW   Reference proteome; Signal; Transmembrane; Transmembrane helix; Transport.
FT   SIGNAL          1..17
FT                   /evidence="ECO:0000255"
FT   CHAIN           18..230
FT                   /note="Protein SOP4"
FT                   /id="PRO_0000324498"
FT   TOPO_DOM        18..187
FT                   /note="Lumenal"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        188..208
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        209..230
FT                   /note="Cytoplasmic"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        32
FT                   /note="N-linked (GlcNAc...) asparagine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        50
FT                   /note="N-linked (GlcNAc...) asparagine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        81
FT                   /note="N-linked (GlcNAc...) asparagine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        115
FT                   /note="N-linked (GlcNAc...) asparagine"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   230 AA;  26951 MW;  C9E4C97E3F3FC36E CRC64;
     MKLLILCLLY YTQLVICNVV SFTGKYSLHP KNLTIDDISR VDFRIYQIGN YTNKPFSQST
     KVNSIDGLFT FNNLPLNRGN NVTTDFVIYS TSLDYNLKPV RILLTYTSWD DEANNHTVKA
     YSNFVGREYF PDKDIIFPDK LEELSMDPYL EVTYFNKAPY RLYYQERNEG ILSTGIIGNI
     LSSRWKTAGV ITMILLIIFP YVVERLDPET SQLLREEVQR KQREKYQIQQ