ID   SOPA_ECO57              Reviewed;         388 AA.
AC   P62557; O82893; P08866;
DT   19-JUL-2004, integrated into UniProtKB/Swiss-Prot.
DT   19-JUL-2004, sequence version 1.
DT   25-MAY-2022, entry version 87.
DE   RecName: Full=Protein SopA;
DE   AltName: Full=Plasmid partition protein A;
GN   Name=sopA; Synonyms=A; OrderedLocusNames=L7068, ECO57PM33;
OS   Escherichia coli O157:H7.
OG   Plasmid pO157.
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Enterobacteriaceae; Escherichia.
OX   NCBI_TaxID=83334;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=O157:H7 / EDL933 / ATCC 700927 / EHEC;
RX   PubMed=9722640; DOI=10.1093/nar/26.18.4196;
RA   Burland V., Shao Y., Perna N.T., Plunkett G. III, Sofia H.J.,
RA   Blattner F.R.;
RT   "The complete DNA sequence and analysis of the large virulence plasmid of
RT   Escherichia coli O157:H7.";
RL   Nucleic Acids Res. 26:4196-4204(1998).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=O157:H7 / Sakai / RIMD 0509952 / EHEC;
RX   PubMed=9628576; DOI=10.1093/dnares/5.1.1;
RA   Makino K., Ishii K., Yasunaga T., Hattori M., Yokoyama K., Yatsudo H.C.,
RA   Kubota Y., Yamaichi Y., Iida T., Yamamoto K., Honda T., Han C.G.,
RA   Ohtsubo A., Kasamatsu M., Hayashi T., Kuhara S., Shinagawa H.;
RT   "Complete nucleotide sequences of 93-kb and 3.3-kb plasmids of an
RT   enterohemorrhagic Escherichia coli O157:H7 derived from Sakai outbreak.";
RL   DNA Res. 5:1-9(1998).
CC   -!- FUNCTION: This protein is essential for plasmid partition. It ensures
CC       the proper distribution of newly replicated plasmids to daughter cells
CC       during cell division. SopA is trans-acting (By similarity).
CC       {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the ParA family. {ECO:0000305}.
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DR   EMBL; AF074613; AAC70136.1; -; Genomic_DNA.
DR   EMBL; AB011549; BAA31790.2; -; Genomic_DNA.
DR   RefSeq; NP_052640.1; NC_002128.1.
DR   RefSeq; WP_000772446.1; NZ_SWKA01000002.1.
DR   AlphaFoldDB; P62557; -.
DR   SMR; P62557; -.
DR   STRING; 155864.EDL933_p0065; -.
DR   EnsemblBacteria; AAC70136; AAC70136; Z_L7068.
DR   EnsemblBacteria; BAA31790; BAA31790; BAA31790.
DR   GeneID; 1789690; -.
DR   KEGG; ece:Z_L7068; -.
DR   KEGG; ecs:pO157p33; -.
DR   PATRIC; fig|386585.9.peg.38; -.
DR   eggNOG; COG1192; Bacteria.
DR   HOGENOM; CLU_037612_9_0_6; -.
DR   OMA; HPIEMTR; -.
DR   Proteomes; UP000000558; Plasmid pO157.
DR   Proteomes; UP000002519; Plasmid pO157.
DR   GO; GO:0030541; P:plasmid partitioning; IEA:UniProtKB-KW.
DR   Gene3D; 3.40.50.300; -; 1.
DR   InterPro; IPR025669; AAA_dom.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   Pfam; PF13614; AAA_31; 1.
DR   SUPFAM; SSF52540; SSF52540; 1.
PE   3: Inferred from homology;
KW   Plasmid; Plasmid partition; Reference proteome.
FT   CHAIN           1..388
FT                   /note="Protein SopA"
FT                   /id="PRO_0000068406"
SQ   SEQUENCE   388 AA;  43660 MW;  89210230B377BD28 CRC64;
     MKLMETLNQC INAGHEMTKA IAIAQFNDDS PEARKITRRW RIGEAADLVG VSSQAIRDAE
     KAGRLPHPDM EIRGRVEQRV GYTIEQINHM RDVFGTRLRR AEDVFPPVIG VAAHKGGVYK
     TSVSVHLAQD LALKGLRVLL VEGNDPQGTA SMYHGWVPDL HIHAEDTLLP FYLGEKDDVT
     YAIKPTCWPG LDIIPSCLAL HRIETELMGK FDEGKLPTDP HLMLRLAIET VAHDYDVIVI
     DSAPNLGIGT INVVCAADVL IVPTPAELFD YTSALQFFDM LRDLLKNVDL KGFEPDVRIL
     LTKYSNSNGS QSPWMEEQIR DAWGSMVLKN VVRETDEVGK GQIRMRTVFE QAIDQRSSTG
     AWRNALSIWE PVCNEIFDRL IKPRWEIR