ID   SOPA_ECOLI              Reviewed;         388 AA.
AC   P62556; O82893; P08866;
DT   19-JUL-2004, integrated into UniProtKB/Swiss-Prot.
DT   19-JUL-2004, sequence version 1.
DT   25-MAY-2022, entry version 90.
DE   RecName: Full=Protein SopA;
DE   AltName: Full=Plasmid partition protein A;
GN   Name=sopA; Synonyms=A; OrderedLocusNames=ECOK12F046;
OS   Escherichia coli (strain K12).
OG   Plasmid F.
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Enterobacteriaceae; Escherichia.
OX   NCBI_TaxID=83333;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=K12;
RX   PubMed=3029390; DOI=10.1016/0022-2836(86)90459-6;
RA   Mori H., Kondo A., Ohshima A., Ogura T., Hiraga S.;
RT   "Structure and function of the F plasmid genes essential for
RT   partitioning.";
RL   J. Mol. Biol. 192:1-15(1986).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RA   Eichenlaub R.;
RT   "F plasmid DNA complete mini-F region (F coordinates 40.301F to 49.869F).";
RL   Submitted (AUG-1986) to the EMBL/GenBank/DDBJ databases.
RN   [3]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=K12 / CR63;
RA   Shimizu H., Saitoh Y., Suda Y., Uehara K., Sampei G., Mizobuchi K.;
RT   "Complete nucleotide sequence of the F plasmid: its implications for
RT   organization and diversification of plasmid genomes.";
RL   Submitted (APR-2000) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: This protein is essential for plasmid partition. It ensures
CC       the proper distribution of newly replicated plasmids to daughter cells
CC       during cell division. SopA is trans-acting.
CC   -!- SIMILARITY: Belongs to the ParA family. {ECO:0000305}.
CC   -!- SEQUENCE CAUTION:
CC       Sequence=AAA24902.1; Type=Erroneous initiation; Evidence={ECO:0000305};
CC       Sequence=BAA97916.1; Type=Erroneous initiation; Evidence={ECO:0000305};
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DR   EMBL; X04619; CAA28295.1; -; Genomic_DNA.
DR   EMBL; M12987; AAA24902.1; ALT_INIT; Genomic_DNA.
DR   EMBL; AP001918; BAA97916.1; ALT_INIT; Genomic_DNA.
DR   PIR; A25783; BVECAF.
DR   PIR; T00243; T00243.
DR   RefSeq; NP_061425.3; NC_002483.1.
DR   RefSeq; WP_000772446.1; NZ_STEB01000056.1.
DR   RefSeq; YP_001294714.2; NC_009602.1.
DR   AlphaFoldDB; P62556; -.
DR   SMR; P62556; -.
DR   PRIDE; P62556; -.
DR   PRO; PR:P62556; -.
DR   GO; GO:0030541; P:plasmid partitioning; IEA:UniProtKB-KW.
DR   Gene3D; 3.40.50.300; -; 1.
DR   InterPro; IPR025669; AAA_dom.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   Pfam; PF13614; AAA_31; 1.
DR   SUPFAM; SSF52540; SSF52540; 1.
PE   3: Inferred from homology;
KW   Plasmid; Plasmid partition.
FT   CHAIN           1..388
FT                   /note="Protein SopA"
FT                   /id="PRO_0000068405"
SQ   SEQUENCE   388 AA;  43660 MW;  89210230B377BD28 CRC64;
     MKLMETLNQC INAGHEMTKA IAIAQFNDDS PEARKITRRW RIGEAADLVG VSSQAIRDAE
     KAGRLPHPDM EIRGRVEQRV GYTIEQINHM RDVFGTRLRR AEDVFPPVIG VAAHKGGVYK
     TSVSVHLAQD LALKGLRVLL VEGNDPQGTA SMYHGWVPDL HIHAEDTLLP FYLGEKDDVT
     YAIKPTCWPG LDIIPSCLAL HRIETELMGK FDEGKLPTDP HLMLRLAIET VAHDYDVIVI
     DSAPNLGIGT INVVCAADVL IVPTPAELFD YTSALQFFDM LRDLLKNVDL KGFEPDVRIL
     LTKYSNSNGS QSPWMEEQIR DAWGSMVLKN VVRETDEVGK GQIRMRTVFE QAIDQRSSTG
     AWRNALSIWE PVCNEIFDRL IKPRWEIR