SOT11_ARATH
ID SOT11_ARATH Reviewed; 351 AA.
AC Q8RV79; Q9ZPQ6;
DT 16-MAY-2012, integrated into UniProtKB/Swiss-Prot.
DT 01-JUN-2002, sequence version 1.
DT 03-AUG-2022, entry version 109.
DE RecName: Full=Cytosolic sulfotransferase 11;
DE Short=AtSOT11;
DE EC=2.8.2.-;
GN Name=SOT11; OrderedLocusNames=At2g03750; ORFNames=F19B11;
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=10617197; DOI=10.1038/45471;
RA Lin X., Kaul S., Rounsley S.D., Shea T.P., Benito M.-I., Town C.D.,
RA Fujii C.Y., Mason T.M., Bowman C.L., Barnstead M.E., Feldblyum T.V.,
RA Buell C.R., Ketchum K.A., Lee J.J., Ronning C.M., Koo H.L., Moffat K.S.,
RA Cronin L.A., Shen M., Pai G., Van Aken S., Umayam L., Tallon L.J.,
RA Gill J.E., Adams M.D., Carrera A.J., Creasy T.H., Goodman H.M.,
RA Somerville C.R., Copenhaver G.P., Preuss D., Nierman W.C., White O.,
RA Eisen J.A., Salzberg S.L., Fraser C.M., Venter J.C.;
RT "Sequence and analysis of chromosome 2 of the plant Arabidopsis thaliana.";
RL Nature 402:761-768(1999).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Columbia;
RX PubMed=14593172; DOI=10.1126/science.1088305;
RA Yamada K., Lim J., Dale J.M., Chen H., Shinn P., Palm C.J., Southwick A.M.,
RA Wu H.C., Kim C.J., Nguyen M., Pham P.K., Cheuk R.F., Karlin-Newmann G.,
RA Liu S.X., Lam B., Sakano H., Wu T., Yu G., Miranda M., Quach H.L.,
RA Tripp M., Chang C.H., Lee J.M., Toriumi M.J., Chan M.M., Tang C.C.,
RA Onodera C.S., Deng J.M., Akiyama K., Ansari Y., Arakawa T., Banh J.,
RA Banno F., Bowser L., Brooks S.Y., Carninci P., Chao Q., Choy N., Enju A.,
RA Goldsmith A.D., Gurjal M., Hansen N.F., Hayashizaki Y., Johnson-Hopson C.,
RA Hsuan V.W., Iida K., Karnes M., Khan S., Koesema E., Ishida J., Jiang P.X.,
RA Jones T., Kawai J., Kamiya A., Meyers C., Nakajima M., Narusaka M.,
RA Seki M., Sakurai T., Satou M., Tamse R., Vaysberg M., Wallender E.K.,
RA Wong C., Yamamura Y., Yuan S., Shinozaki K., Davis R.W., Theologis A.,
RA Ecker J.R.;
RT "Empirical analysis of transcriptional activity in the Arabidopsis
RT genome.";
RL Science 302:842-846(2003).
RN [4]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RA Brover V.V., Troukhan M.E., Alexandrov N.A., Lu Y.-P., Flavell R.B.,
RA Feldmann K.A.;
RT "Full-length cDNA from Arabidopsis thaliana.";
RL Submitted (MAR-2002) to the EMBL/GenBank/DDBJ databases.
RN [5]
RP GENE FAMILY, AND NOMENCLATURE.
RX PubMed=15234990; DOI=10.1093/jxb/erh183;
RA Klein M., Papenbrock J.;
RT "The multi-protein family of Arabidopsis sulphotransferases and their
RT relatives in other plant species.";
RL J. Exp. Bot. 55:1809-1820(2004).
RN [6]
RP DISRUPTION PHENOTYPE.
RX PubMed=20374532; DOI=10.1111/j.1365-3040.2010.02156.x;
RA Baek D., Pathange P., Chung J.S., Jiang J., Gao L., Oikawa A., Hirai M.Y.,
RA Saito K., Pare P.W., Shi H.;
RT "A stress-inducible sulphotransferase sulphonates salicylic acid and
RT confers pathogen resistance in Arabidopsis.";
RL Plant Cell Environ. 33:1383-1392(2010).
CC -!- FUNCTION: Sulfotransferase that utilizes 3'-phospho-5'-adenylyl sulfate
CC (PAPS) as sulfonate donor. {ECO:0000250}.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250}.
CC -!- DISRUPTION PHENOTYPE: No effect on sensitivity to salicylic acid.
CC {ECO:0000269|PubMed:20374532}.
CC -!- SIMILARITY: Belongs to the sulfotransferase 1 family. {ECO:0000305}.
CC -!- SEQUENCE CAUTION:
CC Sequence=AAM65471.1; Type=Erroneous initiation; Note=Truncated N-terminus.; Evidence={ECO:0000305};
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DR EMBL; AC006836; AAD20077.2; -; Genomic_DNA.
DR EMBL; CP002685; AEC05745.1; -; Genomic_DNA.
DR EMBL; AY092961; AAM12960.1; -; mRNA.
DR EMBL; AF325065; AAK17133.1; -; mRNA.
DR EMBL; BT002108; AAN72119.1; -; mRNA.
DR EMBL; AY087921; AAM65471.1; ALT_INIT; mRNA.
DR PIR; H84451; H84451.
DR RefSeq; NP_565305.1; NM_126422.3.
DR AlphaFoldDB; Q8RV79; -.
DR SMR; Q8RV79; -.
DR STRING; 3702.AT2G03750.1; -.
DR iPTMnet; Q8RV79; -.
DR PaxDb; Q8RV79; -.
DR PRIDE; Q8RV79; -.
DR ProteomicsDB; 232627; -.
DR DNASU; 814902; -.
DR EnsemblPlants; AT2G03750.1; AT2G03750.1; AT2G03750.
DR GeneID; 814902; -.
DR Gramene; AT2G03750.1; AT2G03750.1; AT2G03750.
DR KEGG; ath:AT2G03750; -.
DR Araport; AT2G03750; -.
DR TAIR; locus:2044219; AT2G03750.
DR eggNOG; KOG1584; Eukaryota.
DR HOGENOM; CLU_027239_0_1_1; -.
DR InParanoid; Q8RV79; -.
DR OMA; YHGMASF; -.
DR OrthoDB; 780670at2759; -.
DR PhylomeDB; Q8RV79; -.
DR BioCyc; ARA:AT2G03750-MON; -.
DR PRO; PR:Q8RV79; -.
DR Proteomes; UP000006548; Chromosome 2.
DR ExpressionAtlas; Q8RV79; baseline and differential.
DR Genevisible; Q8RV79; AT.
DR GO; GO:0005737; C:cytoplasm; IBA:GO_Central.
DR GO; GO:0008146; F:sulfotransferase activity; IBA:GO_Central.
DR GO; GO:0051923; P:sulfation; IBA:GO_Central.
DR Gene3D; 3.40.50.300; -; 1.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR000863; Sulfotransferase_dom.
DR Pfam; PF00685; Sulfotransfer_1; 1.
DR SUPFAM; SSF52540; SSF52540; 1.
PE 2: Evidence at transcript level;
KW Cytoplasm; Reference proteome; Transferase.
FT CHAIN 1..351
FT /note="Cytosolic sulfotransferase 11"
FT /id="PRO_0000417059"
FT ACT_SITE 163
FT /note="Proton acceptor"
FT /evidence="ECO:0000250"
FT BINDING 98..103
FT /ligand="3'-phosphoadenylyl sulfate"
FT /ligand_id="ChEBI:CHEBI:58339"
FT /evidence="ECO:0000250"
FT BINDING 184
FT /ligand="3'-phosphoadenylyl sulfate"
FT /ligand_id="ChEBI:CHEBI:58339"
FT /evidence="ECO:0000250"
FT BINDING 192
FT /ligand="3'-phosphoadenylyl sulfate"
FT /ligand_id="ChEBI:CHEBI:58339"
FT /evidence="ECO:0000250"
FT BINDING 250
FT /ligand="3'-phosphoadenylyl sulfate"
FT /ligand_id="ChEBI:CHEBI:58339"
FT /evidence="ECO:0000250"
FT BINDING 316..318
FT /ligand="3'-phosphoadenylyl sulfate"
FT /ligand_id="ChEBI:CHEBI:58339"
FT /evidence="ECO:0000250"
SQ SEQUENCE 351 AA; 40838 MW; 2B8B7F61060333FA CRC64;
MFTFFTILSL CFKSWEQIIT MEASKEAHHL PNYMKDDNVS QETKNLITSL PSDKDFMGYG
LYNYKGCWYY PNTLQAVLDV QKHFKPRDTD IILASLPKGG TTWLKSLIFA VVHREKYRGT
PQTHPLLLQN PHDLVPFLEV ELYANSQIPD LAKYSSPMIF STHMHLQALR EATTKACKTV
YVCRGIKDTF VSGWHYRNML HRTKMDQATF ELMFDAYCRG VLLYGPYWEH VLSYWKGSLE
AKENVLFMKY EEIIEEPRVQ VKRLAEFLEC PFTKEEEESG SVEEILKLCS LRNLSNLEVN
KNGTTRIGVD SQVFFRKGEV GDWKNHLTPQ MAKTFDEIID YRLGDSGLIF Q
