SOT13_ARATH
ID SOT13_ARATH Reviewed; 324 AA.
AC Q9ZPQ5;
DT 16-MAY-2012, integrated into UniProtKB/Swiss-Prot.
DT 01-MAY-1999, sequence version 1.
DT 03-AUG-2022, entry version 113.
DE RecName: Full=Cytosolic sulfotransferase 13;
DE Short=AtSOT13;
DE EC=2.8.2.-;
GN Name=SOT13; OrderedLocusNames=At2g03770; ORFNames=F19B11;
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=10617197; DOI=10.1038/45471;
RA Lin X., Kaul S., Rounsley S.D., Shea T.P., Benito M.-I., Town C.D.,
RA Fujii C.Y., Mason T.M., Bowman C.L., Barnstead M.E., Feldblyum T.V.,
RA Buell C.R., Ketchum K.A., Lee J.J., Ronning C.M., Koo H.L., Moffat K.S.,
RA Cronin L.A., Shen M., Pai G., Van Aken S., Umayam L., Tallon L.J.,
RA Gill J.E., Adams M.D., Carrera A.J., Creasy T.H., Goodman H.M.,
RA Somerville C.R., Copenhaver G.P., Preuss D., Nierman W.C., White O.,
RA Eisen J.A., Salzberg S.L., Fraser C.M., Venter J.C.;
RT "Sequence and analysis of chromosome 2 of the plant Arabidopsis thaliana.";
RL Nature 402:761-768(1999).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [3]
RP GENE FAMILY, AND NOMENCLATURE.
RX PubMed=15234990; DOI=10.1093/jxb/erh183;
RA Klein M., Papenbrock J.;
RT "The multi-protein family of Arabidopsis sulphotransferases and their
RT relatives in other plant species.";
RL J. Exp. Bot. 55:1809-1820(2004).
RN [4]
RP DISRUPTION PHENOTYPE.
RX PubMed=20374532; DOI=10.1111/j.1365-3040.2010.02156.x;
RA Baek D., Pathange P., Chung J.S., Jiang J., Gao L., Oikawa A., Hirai M.Y.,
RA Saito K., Pare P.W., Shi H.;
RT "A stress-inducible sulphotransferase sulphonates salicylic acid and
RT confers pathogen resistance in Arabidopsis.";
RL Plant Cell Environ. 33:1383-1392(2010).
CC -!- FUNCTION: Sulfotransferase that utilizes 3'-phospho-5'-adenylyl sulfate
CC (PAPS) as sulfonate donor. {ECO:0000250}.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250}.
CC -!- DISRUPTION PHENOTYPE: No effect on sensitivity to salicylic acid.
CC {ECO:0000269|PubMed:20374532}.
CC -!- SIMILARITY: Belongs to the sulfotransferase 1 family. {ECO:0000305}.
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DR EMBL; AC006836; AAD20079.1; -; Genomic_DNA.
DR EMBL; CP002685; AEC05747.1; -; Genomic_DNA.
DR PIR; B84452; B84452.
DR RefSeq; NP_178472.1; NM_126424.2.
DR AlphaFoldDB; Q9ZPQ5; -.
DR SMR; Q9ZPQ5; -.
DR STRING; 3702.AT2G03770.1; -.
DR PaxDb; Q9ZPQ5; -.
DR PRIDE; Q9ZPQ5; -.
DR ProteomicsDB; 245326; -.
DR DNASU; 814904; -.
DR EnsemblPlants; AT2G03770.1; AT2G03770.1; AT2G03770.
DR GeneID; 814904; -.
DR Gramene; AT2G03770.1; AT2G03770.1; AT2G03770.
DR KEGG; ath:AT2G03770; -.
DR Araport; AT2G03770; -.
DR TAIR; locus:2044249; AT2G03770.
DR eggNOG; KOG1584; Eukaryota.
DR HOGENOM; CLU_027239_0_1_1; -.
DR OMA; MVESCHQ; -.
DR OrthoDB; 780670at2759; -.
DR PhylomeDB; Q9ZPQ5; -.
DR BioCyc; ARA:AT2G03770-MON; -.
DR PRO; PR:Q9ZPQ5; -.
DR Proteomes; UP000006548; Chromosome 2.
DR ExpressionAtlas; Q9ZPQ5; baseline and differential.
DR Genevisible; Q9ZPQ5; AT.
DR GO; GO:0005737; C:cytoplasm; IBA:GO_Central.
DR GO; GO:1990135; F:flavonoid sulfotransferase activity; IDA:TAIR.
DR GO; GO:0008146; F:sulfotransferase activity; IDA:TAIR.
DR GO; GO:0009812; P:flavonoid metabolic process; IDA:TAIR.
DR GO; GO:0051923; P:sulfation; IBA:GO_Central.
DR Gene3D; 3.40.50.300; -; 1.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR000863; Sulfotransferase_dom.
DR Pfam; PF00685; Sulfotransfer_1; 1.
DR SUPFAM; SSF52540; SSF52540; 1.
PE 3: Inferred from homology;
KW Cytoplasm; Reference proteome; Transferase.
FT CHAIN 1..324
FT /note="Cytosolic sulfotransferase 13"
FT /id="PRO_0000417060"
FT ACT_SITE 134
FT /note="Proton acceptor"
FT /evidence="ECO:0000250"
FT BINDING 76..81
FT /ligand="3'-phosphoadenylyl sulfate"
FT /ligand_id="ChEBI:CHEBI:58339"
FT /evidence="ECO:0000250"
FT BINDING 156
FT /ligand="3'-phosphoadenylyl sulfate"
FT /ligand_id="ChEBI:CHEBI:58339"
FT /evidence="ECO:0000250"
FT BINDING 164
FT /ligand="3'-phosphoadenylyl sulfate"
FT /ligand_id="ChEBI:CHEBI:58339"
FT /evidence="ECO:0000250"
FT BINDING 222
FT /ligand="3'-phosphoadenylyl sulfate"
FT /ligand_id="ChEBI:CHEBI:58339"
FT /evidence="ECO:0000250"
FT BINDING 288..290
FT /ligand="3'-phosphoadenylyl sulfate"
FT /ligand_id="ChEBI:CHEBI:58339"
FT /evidence="ECO:0000250"
SQ SEQUENCE 324 AA; 37717 MW; B488C799AB13E1D3 CRC64;
MTKSETTLSK LLVESELVQE CEELLSSLPR DRSVFAEYLY QYQGFWYPPN LLEGVLYSQK
HFQARDSDIV LASIPKSGTT WLKSLVFALI HRQEFQTPLV SHPLLDNNPH TLVTFIEGFH
LHTQDTSPRI FSTHIPVGSL PESVKDSSCK VVYCCRNPKD AFVSLWHFMK NLIVKEMVGC
TMEEMVRFFC RGSSIYGPFW DHVLQYWKES RENPKKVMFV MYEEMREQPQ EWVMRIAEFL
GYSFTEEEIE NGVLEDIIKL CSLENLSKLE VNEKGKLLNG METKAFFRKG EIGGWRDTLT
PLLAEEIDKT TKEKLIGSDF RFFC
