SOT9_ARATH
ID SOT9_ARATH Reviewed; 351 AA.
AC Q9FX55;
DT 16-MAY-2012, integrated into UniProtKB/Swiss-Prot.
DT 01-MAR-2001, sequence version 1.
DT 03-AUG-2022, entry version 116.
DE RecName: Full=Cytosolic sulfotransferase 9;
DE Short=AtSOT9;
DE EC=2.8.2.-;
DE AltName: Full=Sulfotransferase 4c;
DE Short=AtST4b;
GN Name=STO9; Synonyms=ST4C; OrderedLocusNames=At1g13430; ORFNames=F13B4.24;
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=11130712; DOI=10.1038/35048500;
RA Theologis A., Ecker J.R., Palm C.J., Federspiel N.A., Kaul S., White O.,
RA Alonso J., Altafi H., Araujo R., Bowman C.L., Brooks S.Y., Buehler E.,
RA Chan A., Chao Q., Chen H., Cheuk R.F., Chin C.W., Chung M.K., Conn L.,
RA Conway A.B., Conway A.R., Creasy T.H., Dewar K., Dunn P., Etgu P.,
RA Feldblyum T.V., Feng J.-D., Fong B., Fujii C.Y., Gill J.E., Goldsmith A.D.,
RA Haas B., Hansen N.F., Hughes B., Huizar L., Hunter J.L., Jenkins J.,
RA Johnson-Hopson C., Khan S., Khaykin E., Kim C.J., Koo H.L.,
RA Kremenetskaia I., Kurtz D.B., Kwan A., Lam B., Langin-Hooper S., Lee A.,
RA Lee J.M., Lenz C.A., Li J.H., Li Y.-P., Lin X., Liu S.X., Liu Z.A.,
RA Luros J.S., Maiti R., Marziali A., Militscher J., Miranda M., Nguyen M.,
RA Nierman W.C., Osborne B.I., Pai G., Peterson J., Pham P.K., Rizzo M.,
RA Rooney T., Rowley D., Sakano H., Salzberg S.L., Schwartz J.R., Shinn P.,
RA Southwick A.M., Sun H., Tallon L.J., Tambunga G., Toriumi M.J., Town C.D.,
RA Utterback T., Van Aken S., Vaysberg M., Vysotskaia V.S., Walker M., Wu D.,
RA Yu G., Fraser C.M., Venter J.C., Davis R.W.;
RT "Sequence and analysis of chromosome 1 of the plant Arabidopsis thaliana.";
RL Nature 408:816-820(2000).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Columbia;
RX PubMed=11910074; DOI=10.1126/science.1071006;
RA Seki M., Narusaka M., Kamiya A., Ishida J., Satou M., Sakurai T.,
RA Nakajima M., Enju A., Akiyama K., Oono Y., Muramatsu M., Hayashizaki Y.,
RA Kawai J., Carninci P., Itoh M., Ishii Y., Arakawa T., Shibata K.,
RA Shinagawa A., Shinozaki K.;
RT "Functional annotation of a full-length Arabidopsis cDNA collection.";
RL Science 296:141-145(2002).
RN [4]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Columbia;
RX PubMed=14593172; DOI=10.1126/science.1088305;
RA Yamada K., Lim J., Dale J.M., Chen H., Shinn P., Palm C.J., Southwick A.M.,
RA Wu H.C., Kim C.J., Nguyen M., Pham P.K., Cheuk R.F., Karlin-Newmann G.,
RA Liu S.X., Lam B., Sakano H., Wu T., Yu G., Miranda M., Quach H.L.,
RA Tripp M., Chang C.H., Lee J.M., Toriumi M.J., Chan M.M., Tang C.C.,
RA Onodera C.S., Deng J.M., Akiyama K., Ansari Y., Arakawa T., Banh J.,
RA Banno F., Bowser L., Brooks S.Y., Carninci P., Chao Q., Choy N., Enju A.,
RA Goldsmith A.D., Gurjal M., Hansen N.F., Hayashizaki Y., Johnson-Hopson C.,
RA Hsuan V.W., Iida K., Karnes M., Khan S., Koesema E., Ishida J., Jiang P.X.,
RA Jones T., Kawai J., Kamiya A., Meyers C., Nakajima M., Narusaka M.,
RA Seki M., Sakurai T., Satou M., Tamse R., Vaysberg M., Wallender E.K.,
RA Wong C., Yamamura Y., Yuan S., Shinozaki K., Davis R.W., Theologis A.,
RA Ecker J.R.;
RT "Empirical analysis of transcriptional activity in the Arabidopsis
RT genome.";
RL Science 302:842-846(2003).
RN [5]
RP GENE FAMILY, AND NOMENCLATURE.
RX PubMed=15234990; DOI=10.1093/jxb/erh183;
RA Klein M., Papenbrock J.;
RT "The multi-protein family of Arabidopsis sulphotransferases and their
RT relatives in other plant species.";
RL J. Exp. Bot. 55:1809-1820(2004).
RN [6]
RP FUNCTION, INDUCTION BY TRANS-ZEATIN, AND TISSUE SPECIFICITY.
RC STRAIN=cv. Columbia;
RX PubMed=17039368; DOI=10.1007/s00425-006-0413-y;
RA Marsolais F., Boyd J., Paredes Y., Schinas A.M., Garcia M., Elzein S.,
RA Varin L.;
RT "Molecular and biochemical characterization of two brassinosteroid
RT sulfotransferases from Arabidopsis, AtST4a (At2g14920) and AtST1
RT (At2g03760).";
RL Planta 225:1233-1244(2007).
CC -!- FUNCTION: Sulfotransferase that utilizes 3'-phospho-5'-adenylyl sulfate
CC (PAPS) as sulfonate donor. No activity with brassinosteroids.
CC {ECO:0000269|PubMed:17039368}.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250}.
CC -!- TISSUE SPECIFICITY: Expressed in roots and leaves.
CC {ECO:0000269|PubMed:17039368}.
CC -!- INDUCTION: Up-regulated by trans-zeatin. {ECO:0000269|PubMed:17039368}.
CC -!- SIMILARITY: Belongs to the sulfotransferase 1 family. {ECO:0000305}.
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DR EMBL; AC011810; AAG09548.1; -; Genomic_DNA.
DR EMBL; CP002684; AEE29015.1; -; Genomic_DNA.
DR EMBL; AK118984; BAC43560.1; -; mRNA.
DR EMBL; BT006116; AAP04101.1; -; mRNA.
DR RefSeq; NP_172800.2; NM_101213.3.
DR AlphaFoldDB; Q9FX55; -.
DR SMR; Q9FX55; -.
DR BioGRID; 23143; 1.
DR STRING; 3702.AT1G13430.1; -.
DR PaxDb; Q9FX55; -.
DR PRIDE; Q9FX55; -.
DR ProteomicsDB; 245330; -.
DR EnsemblPlants; AT1G13430.1; AT1G13430.1; AT1G13430.
DR GeneID; 837903; -.
DR Gramene; AT1G13430.1; AT1G13430.1; AT1G13430.
DR KEGG; ath:AT1G13430; -.
DR Araport; AT1G13430; -.
DR TAIR; locus:2010027; AT1G13430.
DR eggNOG; KOG1584; Eukaryota.
DR HOGENOM; CLU_027239_0_1_1; -.
DR InParanoid; Q9FX55; -.
DR OMA; GHKICEY; -.
DR OrthoDB; 780670at2759; -.
DR PhylomeDB; Q9FX55; -.
DR BioCyc; ARA:AT1G13430-MON; -.
DR PRO; PR:Q9FX55; -.
DR Proteomes; UP000006548; Chromosome 1.
DR ExpressionAtlas; Q9FX55; baseline and differential.
DR Genevisible; Q9FX55; AT.
DR GO; GO:0005737; C:cytoplasm; IBA:GO_Central.
DR GO; GO:0008146; F:sulfotransferase activity; IBA:GO_Central.
DR GO; GO:0009735; P:response to cytokinin; IEP:TAIR.
DR GO; GO:0051923; P:sulfation; IBA:GO_Central.
DR Gene3D; 3.40.50.300; -; 1.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR000863; Sulfotransferase_dom.
DR Pfam; PF00685; Sulfotransfer_1; 1.
DR SUPFAM; SSF52540; SSF52540; 1.
PE 2: Evidence at transcript level;
KW Cytoplasm; Reference proteome; Transferase.
FT CHAIN 1..351
FT /note="Cytosolic sulfotransferase 9"
FT /id="PRO_0000417057"
FT REGION 1..24
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT ACT_SITE 152
FT /note="Proton acceptor"
FT /evidence="ECO:0000250"
FT BINDING 80..85
FT /ligand="3'-phosphoadenylyl sulfate"
FT /ligand_id="ChEBI:CHEBI:58339"
FT /evidence="ECO:0000250"
FT BINDING 174
FT /ligand="3'-phosphoadenylyl sulfate"
FT /ligand_id="ChEBI:CHEBI:58339"
FT /evidence="ECO:0000250"
FT BINDING 182
FT /ligand="3'-phosphoadenylyl sulfate"
FT /ligand_id="ChEBI:CHEBI:58339"
FT /evidence="ECO:0000250"
FT BINDING 252
FT /ligand="3'-phosphoadenylyl sulfate"
FT /ligand_id="ChEBI:CHEBI:58339"
FT /evidence="ECO:0000250"
FT BINDING 317..319
FT /ligand="3'-phosphoadenylyl sulfate"
FT /ligand_id="ChEBI:CHEBI:58339"
FT /evidence="ECO:0000250"
SQ SEQUENCE 351 AA; 40667 MW; 1591B06D262A3994 CRC64;
MDEKDILRNL REEEEEEEEN QSEETKILIS SLPWEIDYLG NKLFKYQGYW YYEDVLQSIP
NIHSSFQPQE TDIVVASFYK SGTTWLKALT FALVQRSKHS LEDHHHPLLS HNPHEIVPYL
ELDLYLNSSK PDLTKFLSSS SSSSSPRLFS THMSLDALKL PLKKSPCKVV YVCRNVKDVL
VSLWCFLNAN KGVEWGDFSQ NEKIIRAENY SFKAIFESFC NGVTLHGPFW DHAQSYWRGS
LEDPKHFLFM RYEELKAEPR TQVKRLAEFL DCPFTKEEED SGTVDKILEL CSLSNLSSLE
INKTGSLGGV DYKTYFRKGQ VGDWKSYMTS EMVNKIDMIV EEKLKGSGLK F
