SOTB_ENT38
ID SOTB_ENT38 Reviewed; 398 AA.
AC A4WAE6;
DT 05-FEB-2008, integrated into UniProtKB/Swiss-Prot.
DT 29-MAY-2007, sequence version 1.
DT 25-MAY-2022, entry version 90.
DE RecName: Full=Probable sugar efflux transporter {ECO:0000255|HAMAP-Rule:MF_00517};
GN Name=sotB {ECO:0000255|HAMAP-Rule:MF_00517}; OrderedLocusNames=Ent638_2000;
OS Enterobacter sp. (strain 638).
OC Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC Enterobacteriaceae; Enterobacter.
OX NCBI_TaxID=399742;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=638;
RX PubMed=20485560; DOI=10.1371/journal.pgen.1000943;
RA Taghavi S., van der Lelie D., Hoffman A., Zhang Y.B., Walla M.D.,
RA Vangronsveld J., Newman L., Monchy S.;
RT "Genome sequence of the plant growth promoting endophytic bacterium
RT Enterobacter sp. 638.";
RL PLoS Genet. 6:E1000943-E1000943(2010).
CC -!- FUNCTION: Involved in the efflux of sugars. The physiological role may
CC be the reduction of the intracellular concentration of toxic sugars or
CC sugar metabolites. {ECO:0000255|HAMAP-Rule:MF_00517}.
CC -!- SUBCELLULAR LOCATION: Cell inner membrane {ECO:0000255|HAMAP-
CC Rule:MF_00517}; Multi-pass membrane protein {ECO:0000255|HAMAP-
CC Rule:MF_00517}.
CC -!- SIMILARITY: Belongs to the major facilitator superfamily. SotB (TC
CC 2.A.1.2) family. {ECO:0000255|HAMAP-Rule:MF_00517}.
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DR EMBL; CP000653; ABP60676.1; -; Genomic_DNA.
DR RefSeq; WP_012017391.1; NC_009436.1.
DR AlphaFoldDB; A4WAE6; -.
DR SMR; A4WAE6; -.
DR STRING; 399742.Ent638_2000; -.
DR EnsemblBacteria; ABP60676; ABP60676; Ent638_2000.
DR KEGG; ent:Ent638_2000; -.
DR eggNOG; COG2814; Bacteria.
DR HOGENOM; CLU_001265_61_1_6; -.
DR OMA; SAHFTAY; -.
DR OrthoDB; 1384345at2; -.
DR Proteomes; UP000000230; Chromosome.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0015144; F:carbohydrate transmembrane transporter activity; IEA:UniProtKB-UniRule.
DR Gene3D; 1.20.1250.20; -; 1.
DR HAMAP; MF_00517; MFS_SotB; 1.
DR InterPro; IPR011701; MFS.
DR InterPro; IPR020846; MFS_dom.
DR InterPro; IPR036259; MFS_trans_sf.
DR InterPro; IPR023495; Sugar_effux_transptr_put.
DR Pfam; PF07690; MFS_1; 1.
DR SUPFAM; SSF103473; SSF103473; 1.
DR PROSITE; PS50850; MFS; 1.
PE 3: Inferred from homology;
KW Cell inner membrane; Cell membrane; Membrane; Sugar transport;
KW Transmembrane; Transmembrane helix; Transport.
FT CHAIN 1..398
FT /note="Probable sugar efflux transporter"
FT /id="PRO_1000060901"
FT TRANSMEM 15..35
FT /note="Helical"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_00517"
FT TRANSMEM 50..70
FT /note="Helical"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_00517"
FT TRANSMEM 81..101
FT /note="Helical"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_00517"
FT TRANSMEM 103..123
FT /note="Helical"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_00517"
FT TRANSMEM 136..156
FT /note="Helical"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_00517"
FT TRANSMEM 169..189
FT /note="Helical"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_00517"
FT TRANSMEM 209..229
FT /note="Helical"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_00517"
FT TRANSMEM 246..266
FT /note="Helical"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_00517"
FT TRANSMEM 275..295
FT /note="Helical"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_00517"
FT TRANSMEM 301..321
FT /note="Helical"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_00517"
FT TRANSMEM 333..353
FT /note="Helical"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_00517"
FT TRANSMEM 364..384
FT /note="Helical"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_00517"
SQ SEQUENCE 398 AA; 42580 MW; A0275069608DB3BE CRC64;
MTTNTVSRKV AWLRVVTLAI AAFIFNTTEF VPVGLLSDIA QSFQMETAQV GIMLTIYAWV
VALMSLPFML LTSQMERRKL LIGLFVLFIA SHVLSFLAWN FNVLVISRIG IAFAHAIFWS
ITASLAIRLA PAGKRAQALS LLATGTALAM VLGLPIGRIV GQYFGWRTTF FAIGLGALIT
LLCLIKLLPK LPSEHSGSLK SLPLLFRRPA LMSIYLLTVV VVTAHYTAYS YIEPFVQVVA
GFSANFATVL LLILGGAGII GSVLFGKLGN KHASLLVSSA IGLLLACLLL LMPAAQSETH
LAILSIFWGV AIMIIGLGMQ VKVLALAPDA TDVAMSLFSG IFNIGIGAGA LVGNQISLHL
SMSAIGYLGA IPALAALIWS ILIFRKWPVA LEEQPHHG