SOTB_PSEE4
ID SOTB_PSEE4 Reviewed; 400 AA.
AC Q1IB51;
DT 15-JAN-2008, integrated into UniProtKB/Swiss-Prot.
DT 13-JUN-2006, sequence version 1.
DT 25-MAY-2022, entry version 92.
DE RecName: Full=Probable sugar efflux transporter {ECO:0000255|HAMAP-Rule:MF_00517};
GN Name=sotB {ECO:0000255|HAMAP-Rule:MF_00517}; OrderedLocusNames=PSEEN2302;
OS Pseudomonas entomophila (strain L48).
OC Bacteria; Proteobacteria; Gammaproteobacteria; Pseudomonadales;
OC Pseudomonadaceae; Pseudomonas.
OX NCBI_TaxID=384676;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=L48;
RX PubMed=16699499; DOI=10.1038/nbt1212;
RA Vodovar N., Vallenet D., Cruveiller S., Rouy Z., Barbe V., Acosta C.,
RA Cattolico L., Jubin C., Lajus A., Segurens B., Vacherie B., Wincker P.,
RA Weissenbach J., Lemaitre B., Medigue C., Boccard F.;
RT "Complete genome sequence of the entomopathogenic and metabolically
RT versatile soil bacterium Pseudomonas entomophila.";
RL Nat. Biotechnol. 24:673-679(2006).
CC -!- FUNCTION: Involved in the efflux of sugars. The physiological role may
CC be the reduction of the intracellular concentration of toxic sugars or
CC sugar metabolites. {ECO:0000255|HAMAP-Rule:MF_00517}.
CC -!- SUBCELLULAR LOCATION: Cell inner membrane {ECO:0000255|HAMAP-
CC Rule:MF_00517}; Multi-pass membrane protein {ECO:0000255|HAMAP-
CC Rule:MF_00517}.
CC -!- SIMILARITY: Belongs to the major facilitator superfamily. SotB (TC
CC 2.A.1.2) family. {ECO:0000255|HAMAP-Rule:MF_00517}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; CT573326; CAK15115.1; -; Genomic_DNA.
DR RefSeq; WP_011533515.1; NC_008027.1.
DR AlphaFoldDB; Q1IB51; -.
DR SMR; Q1IB51; -.
DR STRING; 384676.PSEEN2302; -.
DR EnsemblBacteria; CAK15115; CAK15115; PSEEN2302.
DR KEGG; pen:PSEEN2302; -.
DR eggNOG; COG2814; Bacteria.
DR HOGENOM; CLU_001265_61_1_6; -.
DR OMA; SAHFTAY; -.
DR OrthoDB; 1384345at2; -.
DR Proteomes; UP000000658; Chromosome.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0015144; F:carbohydrate transmembrane transporter activity; IEA:UniProtKB-UniRule.
DR Gene3D; 1.20.1250.20; -; 1.
DR HAMAP; MF_00517; MFS_SotB; 1.
DR InterPro; IPR011701; MFS.
DR InterPro; IPR020846; MFS_dom.
DR InterPro; IPR036259; MFS_trans_sf.
DR InterPro; IPR023495; Sugar_effux_transptr_put.
DR Pfam; PF07690; MFS_1; 1.
DR SUPFAM; SSF103473; SSF103473; 1.
DR PROSITE; PS50850; MFS; 1.
PE 3: Inferred from homology;
KW Cell inner membrane; Cell membrane; Membrane; Sugar transport;
KW Transmembrane; Transmembrane helix; Transport.
FT CHAIN 1..400
FT /note="Probable sugar efflux transporter"
FT /id="PRO_1000050802"
FT TRANSMEM 13..31
FT /note="Helical"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_00517"
FT TRANSMEM 56..76
FT /note="Helical"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_00517"
FT TRANSMEM 87..107
FT /note="Helical"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_00517"
FT TRANSMEM 108..128
FT /note="Helical"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_00517"
FT TRANSMEM 142..162
FT /note="Helical"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_00517"
FT TRANSMEM 174..194
FT /note="Helical"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_00517"
FT TRANSMEM 215..235
FT /note="Helical"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_00517"
FT TRANSMEM 254..274
FT /note="Helical"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_00517"
FT TRANSMEM 281..301
FT /note="Helical"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_00517"
FT TRANSMEM 304..324
FT /note="Helical"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_00517"
FT TRANSMEM 339..359
FT /note="Helical"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_00517"
FT TRANSMEM 368..388
FT /note="Helical"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_00517"
SQ SEQUENCE 400 AA; 42149 MW; 04765EF860CF7FA0 CRC64;
MNGPVPSNLP PTAGNGSWLS VIALALAAFI FNTTEFVPVA LLSDIGRSFD MTTAQVGLML
TIYAWVVALA SLPMMLMTRN IERRRLLLFV FVVFILSHLM SWLSQSFAML LVSRIGIALA
HAVFWAITAS LAVRVAPPGQ QAKALGLLAT GTTLAMVMGI PLGRVVGEAL GWRITFLCIA
GVALATMLCL MKSLPLLPSQ NSGSLRSLPI LFKRPALVIT YLLVTLVITA QFTAYSYIEP
FALHVAQIGG ERTTLLLLLF GGAGVFGSLL FSRYSERFPH GFLVMAIAAL AACLLLLLPL
SGNFYLFAGL SMVWGMAILS FGLALQSKTL KLASDATDVA MALFSGIYNI GIGGGALLGS
IVSSQLGVAD IGLIGGGVAL VGLVLALASA RRFREALGKG