ID   SOTB_PSEPW              Reviewed;         399 AA.
AC   B1J9Y3;
DT   14-APR-2009, integrated into UniProtKB/Swiss-Prot.
DT   29-APR-2008, sequence version 1.
DT   25-MAY-2022, entry version 75.
DE   RecName: Full=Probable sugar efflux transporter {ECO:0000255|HAMAP-Rule:MF_00517};
GN   Name=sotB {ECO:0000255|HAMAP-Rule:MF_00517};
GN   OrderedLocusNames=PputW619_3070;
OS   Pseudomonas putida (strain W619).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Pseudomonadales;
OC   Pseudomonadaceae; Pseudomonas.
OX   NCBI_TaxID=390235;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=W619;
RA   Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C.,
RA   Glavina del Rio T., Dalin E., Tice H., Pitluck S., Chain P., Malfatti S.,
RA   Shin M., Vergez L., Schmutz J., Larimer F., Land M., Hauser L.,
RA   Kyrpides N., Kim E., Taghavi S., Vangronsveld D., van der Lelie D.,
RA   Richardson P.;
RT   "Complete sequence of Pseudomonas putida W619.";
RL   Submitted (FEB-2008) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Involved in the efflux of sugars. The physiological role may
CC       be the reduction of the intracellular concentration of toxic sugars or
CC       sugar metabolites. {ECO:0000255|HAMAP-Rule:MF_00517}.
CC   -!- SUBCELLULAR LOCATION: Cell inner membrane {ECO:0000255|HAMAP-
CC       Rule:MF_00517}; Multi-pass membrane protein {ECO:0000255|HAMAP-
CC       Rule:MF_00517}.
CC   -!- SIMILARITY: Belongs to the major facilitator superfamily. SotB (TC
CC       2.A.1.2) family. {ECO:0000255|HAMAP-Rule:MF_00517}.
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DR   EMBL; CP000949; ACA73560.1; -; Genomic_DNA.
DR   RefSeq; WP_012314917.1; NC_010501.1.
DR   AlphaFoldDB; B1J9Y3; -.
DR   SMR; B1J9Y3; -.
DR   STRING; 390235.PputW619_3070; -.
DR   EnsemblBacteria; ACA73560; ACA73560; PputW619_3070.
DR   KEGG; ppw:PputW619_3070; -.
DR   eggNOG; COG2814; Bacteria.
DR   HOGENOM; CLU_001265_61_1_6; -.
DR   OMA; SAHFTAY; -.
DR   OrthoDB; 1384345at2; -.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0015144; F:carbohydrate transmembrane transporter activity; IEA:UniProtKB-UniRule.
DR   Gene3D; 1.20.1250.20; -; 1.
DR   HAMAP; MF_00517; MFS_SotB; 1.
DR   InterPro; IPR011701; MFS.
DR   InterPro; IPR020846; MFS_dom.
DR   InterPro; IPR036259; MFS_trans_sf.
DR   InterPro; IPR023495; Sugar_effux_transptr_put.
DR   Pfam; PF07690; MFS_1; 1.
DR   SUPFAM; SSF103473; SSF103473; 1.
DR   PROSITE; PS50850; MFS; 1.
PE   3: Inferred from homology;
KW   Cell inner membrane; Cell membrane; Membrane; Sugar transport;
KW   Transmembrane; Transmembrane helix; Transport.
FT   CHAIN           1..399
FT                   /note="Probable sugar efflux transporter"
FT                   /id="PRO_1000127468"
FT   TRANSMEM        21..41
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_00517"
FT   TRANSMEM        56..76
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_00517"
FT   TRANSMEM        87..107
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_00517"
FT   TRANSMEM        115..135
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_00517"
FT   TRANSMEM        142..162
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_00517"
FT   TRANSMEM        176..196
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_00517"
FT   TRANSMEM        215..235
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_00517"
FT   TRANSMEM        252..272
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_00517"
FT   TRANSMEM        281..301
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_00517"
FT   TRANSMEM        304..324
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_00517"
FT   TRANSMEM        339..359
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_00517"
FT   TRANSMEM        366..386
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_00517"
SQ   SEQUENCE   399 AA;  42049 MW;  E26B8B1C53EBE0B4 CRC64;
     MNGPVPTNLA PTTGGGSWLS VIALALAAFI FNTTEFVPVA LLSDIGRSFD MSTAQVGLML
     TIYAWVVALA SLPMMLLTRN IERRRLLLFV FLVFVVSHLL SWLSQSFAML LLSRIGIALA
     HAVFWSITAS LAVRVAPPGQ QAKALGLLAT GTTLAMVLGI PLGRVVGEAL GWRVTFLSIA
     GVALATMLCL MKSLPLLPSQ NSGSLRSLPI LFKRPALVIT YVLVTLVITA QFTAYSYIEP
     FALQVAQISG ERITLLLLLF GGAGVFGSVL FSRYSDRFPH GLLVGSIGLL AACLLLLLPL
     AGNFYLFAGL SMFWGVAILS FSLSLQSKTL KLASDATDVA MALFSGIYNI GIGGGALLGS
     IVSSQLGVAS VGWAGGSVAV VGLLLAMAST RRFREALSH