ID   SOTB_PSESM              Reviewed;         407 AA.
AC   Q888L8;
DT   26-APR-2004, integrated into UniProtKB/Swiss-Prot.
DT   01-JUN-2003, sequence version 1.
DT   25-MAY-2022, entry version 102.
DE   RecName: Full=Probable sugar efflux transporter {ECO:0000255|HAMAP-Rule:MF_00517};
GN   Name=sotB {ECO:0000255|HAMAP-Rule:MF_00517}; OrderedLocusNames=PSPTO_0999;
OS   Pseudomonas syringae pv. tomato (strain ATCC BAA-871 / DC3000).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Pseudomonadales;
OC   Pseudomonadaceae; Pseudomonas.
OX   NCBI_TaxID=223283;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC BAA-871 / DC3000;
RX   PubMed=12928499; DOI=10.1073/pnas.1731982100;
RA   Buell C.R., Joardar V., Lindeberg M., Selengut J., Paulsen I.T.,
RA   Gwinn M.L., Dodson R.J., DeBoy R.T., Durkin A.S., Kolonay J.F., Madupu R.,
RA   Daugherty S.C., Brinkac L.M., Beanan M.J., Haft D.H., Nelson W.C.,
RA   Davidsen T.M., Zafar N., Zhou L., Liu J., Yuan Q., Khouri H.M.,
RA   Fedorova N.B., Tran B., Russell D., Berry K.J., Utterback T.R.,
RA   Van Aken S.E., Feldblyum T.V., D'Ascenzo M., Deng W.-L., Ramos A.R.,
RA   Alfano J.R., Cartinhour S., Chatterjee A.K., Delaney T.P., Lazarowitz S.G.,
RA   Martin G.B., Schneider D.J., Tang X., Bender C.L., White O., Fraser C.M.,
RA   Collmer A.;
RT   "The complete genome sequence of the Arabidopsis and tomato pathogen
RT   Pseudomonas syringae pv. tomato DC3000.";
RL   Proc. Natl. Acad. Sci. U.S.A. 100:10181-10186(2003).
CC   -!- FUNCTION: Involved in the efflux of sugars. The physiological role may
CC       be the reduction of the intracellular concentration of toxic sugars or
CC       sugar metabolites. {ECO:0000255|HAMAP-Rule:MF_00517}.
CC   -!- SUBCELLULAR LOCATION: Cell inner membrane {ECO:0000255|HAMAP-
CC       Rule:MF_00517}; Multi-pass membrane protein {ECO:0000255|HAMAP-
CC       Rule:MF_00517}.
CC   -!- SIMILARITY: Belongs to the major facilitator superfamily. SotB (TC
CC       2.A.1.2) family. {ECO:0000255|HAMAP-Rule:MF_00517}.
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DR   EMBL; AE016853; AAO54533.1; -; Genomic_DNA.
DR   RefSeq; NP_790838.1; NC_004578.1.
DR   RefSeq; WP_005771500.1; NC_004578.1.
DR   AlphaFoldDB; Q888L8; -.
DR   SMR; Q888L8; -.
DR   STRING; 223283.PSPTO_0999; -.
DR   EnsemblBacteria; AAO54533; AAO54533; PSPTO_0999.
DR   GeneID; 1182633; -.
DR   KEGG; pst:PSPTO_0999; -.
DR   PATRIC; fig|223283.9.peg.1009; -.
DR   eggNOG; COG2814; Bacteria.
DR   HOGENOM; CLU_001265_61_1_6; -.
DR   OMA; SAHFTAY; -.
DR   OrthoDB; 1384345at2; -.
DR   PhylomeDB; Q888L8; -.
DR   Proteomes; UP000002515; Chromosome.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0015144; F:carbohydrate transmembrane transporter activity; IEA:UniProtKB-UniRule.
DR   Gene3D; 1.20.1250.20; -; 1.
DR   HAMAP; MF_00517; MFS_SotB; 1.
DR   InterPro; IPR011701; MFS.
DR   InterPro; IPR020846; MFS_dom.
DR   InterPro; IPR036259; MFS_trans_sf.
DR   InterPro; IPR023495; Sugar_effux_transptr_put.
DR   Pfam; PF07690; MFS_1; 1.
DR   SUPFAM; SSF103473; SSF103473; 1.
DR   PROSITE; PS50850; MFS; 1.
PE   3: Inferred from homology;
KW   Cell inner membrane; Cell membrane; Membrane; Reference proteome;
KW   Sugar transport; Transmembrane; Transmembrane helix; Transport.
FT   CHAIN           1..407
FT                   /note="Probable sugar efflux transporter"
FT                   /id="PRO_0000209333"
FT   TRANSMEM        18..38
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_00517"
FT   TRANSMEM        55..75
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_00517"
FT   TRANSMEM        88..108
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_00517"
FT   TRANSMEM        114..134
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_00517"
FT   TRANSMEM        141..161
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_00517"
FT   TRANSMEM        175..195
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_00517"
FT   TRANSMEM        217..237
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_00517"
FT   TRANSMEM        253..273
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_00517"
FT   TRANSMEM        280..300
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_00517"
FT   TRANSMEM        304..324
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_00517"
FT   TRANSMEM        338..358
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_00517"
FT   TRANSMEM        365..385
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_00517"
SQ   SEQUENCE   407 AA;  42774 MW;  DD1589C777A6FD67 CRC64;
     MITSPPNEQT GEHTGSWLGV FALALAAFIF NTTEFVPIGL LSNIGQSFDM TPAQVGLMLT
     IYAWVVSLMS LPMMLATRNI ERRKLLMFVF GLFVVSHVIS AMASSFAILL VSRVGIAFAH
     AVFWSVTASL AVRIAPPGKQ VQALGLLATG TSLAMVLGIP LGRVLGEALG WRTTFLGIAG
     VAALVVFLLA RALPLLPSQN SGSLRSLPIL FKRPRLMAIY LLTAIVVTAH FTAYSYIEPF
     TQTVSRLSGE MTTILLLVFG GAGIMGSIVF SLFSDRFPNG LLITAIGTLA VCLLMLLPLS
     GDATMLGTLT VVWGMAIMCF GLLLQARVLS LAPDATDVAM ALFSGIFNIG IGGGALLGSV
     VSSHLGVANV GIVGGLLALG GLGLICYTTF LFGKTQPHAE MQADAKH