ID   SOX16_MOUSE             Reviewed;          57 AA.
AC   Q62247;
DT   15-JUL-1998, integrated into UniProtKB/Swiss-Prot.
DT   01-NOV-1996, sequence version 1.
DT   25-MAY-2022, entry version 104.
DE   RecName: Full=Protein SOX-16;
DE   Flags: Fragment;
GN   Name=Sox16;
OS   Mus musculus (Mouse).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae;
OC   Murinae; Mus; Mus.
OX   NCBI_TaxID=10090;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [MRNA].
RC   TISSUE=Bone marrow;
RA   Layfield R., Mynett-Johnson L., Yarwood P.J., Muscat G.E.O., Koopman P.A.,
RA   Hume D.A.;
RL   Submitted (FEB-1994) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000255|PROSITE-ProRule:PRU00267}.
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DR   EMBL; L29084; AAA56842.1; -; mRNA.
DR   AlphaFoldDB; Q62247; -.
DR   SMR; Q62247; -.
DR   MaxQB; Q62247; -.
DR   PRIDE; Q62247; -.
DR   MGI; MGI:1890761; Sox16.
DR   InParanoid; Q62247; -.
DR   Proteomes; UP000000589; Unplaced.
DR   RNAct; Q62247; protein.
DR   GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR   GO; GO:0000981; F:DNA-binding transcription factor activity, RNA polymerase II-specific; IBA:GO_Central.
DR   GO; GO:0000978; F:RNA polymerase II cis-regulatory region sequence-specific DNA binding; IBA:GO_Central.
DR   GO; GO:0009653; P:anatomical structure morphogenesis; IBA:GO_Central.
DR   GO; GO:0030154; P:cell differentiation; IBA:GO_Central.
DR   GO; GO:0000122; P:negative regulation of transcription by RNA polymerase II; IBA:GO_Central.
DR   GO; GO:0045944; P:positive regulation of transcription by RNA polymerase II; IBA:GO_Central.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IBA:GO_Central.
DR   Gene3D; 1.10.30.10; -; 1.
DR   InterPro; IPR009071; HMG_box_dom.
DR   InterPro; IPR036910; HMG_box_dom_sf.
DR   InterPro; IPR031269; SOX15.
DR   PANTHER; PTHR10270:SF45; PTHR10270:SF45; 1.
DR   Pfam; PF00505; HMG_box; 1.
DR   SMART; SM00398; HMG; 1.
DR   SUPFAM; SSF47095; SSF47095; 1.
DR   PROSITE; PS50118; HMG_BOX_2; 1.
PE   2: Evidence at transcript level;
KW   DNA-binding; Nucleus; Reference proteome.
FT   CHAIN           <1..>57
FT                   /note="Protein SOX-16"
FT                   /id="PRO_0000048764"
FT   DNA_BIND        <1..>57
FT                   /note="HMG box"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00267"
FT   REGION          1..24
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        1..21
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   NON_TER         1
FT   NON_TER         57
SQ   SEQUENCE   57 AA;  6932 MW;  BB8E0471BC27EEC9 CRC64;
     MVWSSAQRRQ MAQQNPKMHN SEISKRLGAQ WKLLDDEEKR PFVEEAKRLR ARHLHDY